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United Kingdom - Scottish nurse treated for Ebola 'complication' - full recovery from Ebola , discharged

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  • #31
    http://www.theguardian.com/world/201...-free-hospital


    Ebola nurse Pauline Cafferkey nearly died from meningitis, doctors say



    Doctors say British nurse has long recovery ahead of her after suffering meningitis brought on by lingering Ebola infection

    [snip]

    Because of her history, they then tested her blood and found “very low levels of the virus, the sort of levels you would see in patients that were about to recover”.

    Every step that followed from that was precautionary.

    ?We didn?t know what the trajectory was ? if the virus in the blood was heralding the fact that something was going to happen or was it just what we would call incidental because we have never seen anything like this before, we were not sure what was going to happen whether this was going to turn into full blown Ebola virus and let?s be absolutely clear about this, it did not,? said Jacobs.

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    • #32
      Pauline Cafferkey has improved

      21 October 2015

      Doctors at the Royal Free Hospital have confirmed that Pauline Cafferkey’s condition improved significantly.

      At a press conference today Dr Michael Jacobs said that she is unwell with viral meningitis caused by her original Ebola infection.

      Pauline was first admitted to the high level isolation unit (HLIU) at the Royal Free Hospital in December 2014 after contracting the disease while working in Sierra Leone. She was discharged in January this year after making a recovery.

      On 8 October 2015 she was re-admitted to the HLIU after developing late complications from her Ebola infection.

      Dr Jacobs said: “I am really pleased she has made a significant improvement. She is inside the tent, she is still in bed, but she is talking freely within the tent. She has got a long recovery ahead of her and she will be with us for quite a while.”

      After careful consideration Pauline decided she would take the experimental drug GS-5734, which is an anti-viral drug.

      Dr Jacobs added: “I am hopeful Pauline will make a full recovery – maybe it will be with the help of this anti-viral drug, maybe it will be down to her own immune system. Over time I anticipate that the virus will be eradicated from her completely.”

      ENDS

      https://www.royalfree.nhs.uk/news-me...t-improvement/

      "Safety and security don't just happen, they are the result of collective consensus and public investment. We owe our children, the most vulnerable citizens in our society, a life free of violence and fear."
      -Nelson Mandela

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      • #33

        Gilead discloses development of experimental Ebola drug GS-5734

        (Ref: The Wall Street Journal, The Guardian, Business Insider, NBC News, StreetInsider, Gilead Sciences) October 21st, 2015
        By: Joe Barber
        ...

        Gilead, which disclosed that it shipped doses of GS-5734 to the Royal Free Hospital in London last week following a request for compassionate access to the drug, noted that in animal studies, GS-5734 was associated with 100 percent survival in monkeys treated with the medicine three days after exposure to the Ebola virus.
        Mike Jacobs, an infectious diseases consultant at Royal Free Hospital, noted that the nurse, who was initially diagnosed with Ebola in December last year, had not been re-infected with the disease since her prior treatment, but that instead, the virus persisted in her brain despite treatment, leading to viral meningitis. "The virus re-emerged around the brain and around the spinal column to cause meningitis," Jacobs explained, adding "she developed some serious neurological complications."...
        Her treatments for the initial infection are reported as:

        If you keep getting sick all the time, or notice that you’re getting one infection after another, there could be an underlying cause.

        By Peter Russell
        WebMD Health News
        Reviewed by Brunilda Nazario, MD


        Jan. 26, 2015
        ...
        Both health care workers were treated by Michael Jacobs, PhD, an infectious diseases consultant at the Royal Free. Pooley received the experimental drug ZMapp. Cafferkey was reportedly treated with an alternative antiviral drug called ZMabb, because supplies of ZMapp had run out.
        Those who received ZMapp and survived are not reporting chronic or relapsing illness as far as I know.

        Ms. Cafferkey is also reported to have had serum antibodies and an antiviral drug as part of here initial infection treatment:
        _____________________________________________

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        • #34
          Pauline Cafferkey discharged

          12 November 2015
          We are pleased to announce that Pauline Cafferkey was discharged from the care of the Royal Free Hospital on 11 November and has been transferred to Queen Elizabeth University Hospital in Glasgow.

          We are delighted that Pauline has made a full recovery from Ebola and is now well enough to return to Scotland. We would like to wish her well for the future.

          Pauline Cafferkey said: “I am forever thankful for the amazing care I have received at the Royal Free Hospital. For a second time staff across many departments of the hospital have worked incredibly hard to help me recover and I will always be grateful to them and the NHS.

          “I am looking forward to returning to Scotland and to seeing my family and friends again.”

          ENDS

          https://www.royalfree.nhs.uk/news-me...ey-discharged/

          "Safety and security don't just happen, they are the result of collective consensus and public investment. We owe our children, the most vulnerable citizens in our society, a life free of violence and fear."
          -Nelson Mandela

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