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U.S. hospitals report rise in severe strep A infections in kids after 15 deaths in U.K.

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  • U.S. hospitals report rise in severe strep A infections in kids after 15 deaths in U.K.


    Dec. 14, 2022, 4:02 PM CST / Updated Dec. 15, 2022, 1:23 PM CST
    By Aria Bendix

    Several children's hospitals in the U.S. have detected increases in invasive group A strep infections, a severe and sometimes life-threatening illness that occurs when bacteria spread to areas of the body that are normally germ-free, such as the bloodstream.

    Children's hospitals in Arizona, Colorado, Texas and Washington told NBC News they are seeing higher-than-average numbers of cases this season compared to past years.

    Two young children in the Denver metro area have died since Nov. 1, according to Colorado's public health department. Eleven cases of severe or invasive strep infections in children up to 6 years old have been identified in the Denver area in that time, the department added. In a typical year, Denver sees one or two such pediatric cases per month.

    Dr. James Versalovic, the pathologist-in-chief at Texas Children’s Hospital in Houston, said his facility — the largest pediatric hospital in the U.S. — has seen "a greater than fourfold increase" in potentially invasive infections in the last two months compared to the same period last year.

    Texas Children’s recorded around 60 cases in October and November, he said. ...

    ... The World Health Organization said Thursday that France, Ireland, the Netherlands and Sweden are seeing cases increase as well, but that the risk to the general population is low.

    The Centers for Disease Control and Prevention, meanwhile, said it is “hearing anecdotes from some U.S. doctors of a possible increase in [invasive group A strep] infections among children in the United States” and is “talking with surveillance sites and hospitals in multiple states to learn more.”

    ... Some people with invasive strep A may develop those conditions, as well, but in many cases the first sign is a secondary infection, like pneumonia or flesh-eating disease.

    “These are cases beyond an ordinary strep throat,” Versalovic said.

    An invasive infection can trigger the following:
    • Lower airway infections like pneumonia or empyema, which are characterized by pockets of pus in the fluid-filled space surrounding the lungs. Early signs of such infections include fever, chills, difficulty breathing or chest pain.
    • Skin infections like cellulitis or necrotizing fasciitis, also known as flesh-eating disease. Both conditions involve red, warm, swollen or painful rashes. Necrotizing fasciitis spreads quickly and can turn into ulcers, blisters or black spots.
    • Streptococcal toxic shock syndrome, an immune reaction that can lead to organ failure. The condition often begins with fever, chills, muscle aches, nausea or vomiting and then causes rapid heart rate or breathing.
    Anyone can get invasive strep A, including healthy adults, but people over 65 and those with chronic illnesses are more susceptible. It is not yet clear why hospitals are seeing an uptick in cases among kids in particular. The CDC said it may be related to the rollback of Covid mitigation measures and the surge of respiratory viruses like flu, Covid and RSV.

    Two young children in Colorado have died from invasive group A strep, and four children's hospitals are seeing more cases than usual.


  • #2
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    • #3
      Source: https://www.dailymail.co.uk/health/a...-symptoms.html

      Strep A outbreak worsens as seven children in Missouri come down with bizarre symptoms including drooling, crossed eyes and lumps behind their ears
      Children's Mercy Kansas City Hospital reported seven unusual Strep A cases
      Hospital staff said they had not seen this many cases so close together before
      It is the sixth US hospital to report abnormal Strep A patterns in recent weeks
      By Mansur Shaheen Deputy Health Editor For Dailymail.Com
      Published: 12:31 EST, 21 December 2022 | Updated: 15:53 EST, 21 December 2022

      One of the largest children's hospitals in Missouri is seeing an influx of children with bizarre Strep A symptoms - as the outbreak continues to spread in the US.

      Children's Mercy Kansas City Hospital has had seven children in recent weeks come in with symptoms like a 'stuck' eye, lumps behind the ear and trouble swallowing - which led to drooling.

      Doctors were initially perplexed by the cases - but further testing found each child was suffering from Strep A. The normally-mild bacterial infection is causing a spate of hospitalizations across the US, UK and Europe.

      The Missouri doctors note that these are not typical symptoms of Strep A infection. Some experts fear lockdowns have robbed children of immunity from common infections, making cases of Strep A and other infections more severe that usual.

      Just two Strep A deaths in children have been confirmed in the outbreak so far - both in Colorado - but officials in six states, have reported a surge in hospital admissions in recent weeks. Across the pond, 19 children have died from the illness in the UK...

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      • #4
        Source: https://emergency.cdc.gov/han/2022/han00484.asp

        Increase in Pediatric Invasive Group A Streptococcal Infections
        Distributed via the CDC Health Alert Network
        December 22, 2022, 1:45 PM ET
        CDCHAN-00484

        Summary
        The Centers for Disease Control and Prevention (CDC) is issuing this Health Alert Network (HAN) Health Advisory to notify clinicians and public health authorities of a recent increase in pediatric invasive group A streptococcal (iGAS) infections. In November 2022, CDC was notified of a possible increase in iGAS infections among children at a hospital in Colorado. Potential increases in pediatric iGAS cases in other states were subsequently noted by contributors to the Infectious Diseases Society of America’s provider-based Emerging Infections Network and by certain jurisdictions participating in CDC’s Active Bacterial Core Surveillance System (ABCs). This increased number of pediatric iGAS cases in some jurisdictions has occurred in the setting of increased circulation of respiratory syncytial virus (RSV), influenza viruses, SARS-CoV-2, and other respiratory viruses. While the overall number of cases has remained relatively low and iGAS infections remain rare in children, CDC is investigating these reports...

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        • #5
          Please see:

          CDC Health Alert Network. December 22, 2022: Increase in Pediatric Invasive Group A Streptococcal Infections

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          • #6
            Source: https://www.woodtv.com/news/grand-ra...strep-a-cases/

            West Michigan doctors see rise in strep A cases
            by: Kyle Mitchell
            Posted: Jan 5, 2023 / 05:38 PM EST
            Updated: Jan 5, 2023 / 06:10 PM EST


            GRAND RAPIDS, Mich. (WOOD) — Helen DeVos Children’s Hospital is seeing an increase in strep A infections and has had recent deaths in West Michigan children.

            Invasive group A strep infections are still rare, but doctors say they can lead to serious complications or death and want more people to be aware.

            Dr. George Fogg, a pediatric infectious disease specialist, said strep A infections are when a strep infection goes beyond the places the bacteria is typically found in a standard strep throat infection.

            “If this bacteria gets into kind the wrong part of your body or wrong compartment in your body it can actually cause a very severe and rapidly progressing infection. This bacteria sort of produces a lot of toxins and is very pro-inflammatory, so it can cause a lot of tissue destruction,” Fogg said.

            Fogg said the pediatric hospital has seen deaths in the past few months. Doctors have treated four cases of strep A in the last month and on average see less than five case in a year...

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