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Micronutrient Facts

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  • Micronutrient Facts

    Micronutrient Facts


    Vitamin A

    "Improved vitamin A nutrition could prevent up to 2.5 million deaths annually among children under 5 years." Vitamin A for the Children of the World Task Force Sight and Life, 2000.


    * Vitamin A deficiency causes night blindness and is the single most important cause of childhood blindness in developing countries. Every year, about 500,000 children lose their sight as a result of vitamin A deficiency. The majority (about 70%) die within one year of losing their sight.

    *Vitamin A deficiency increases the risk of severe illness, and even death, from common childhood infections such as diarrheal diseases and measles. In developing countries 200?300 million children of preschool age are at risk of vitamin A deficiency.

    * Vitamin A deficiency may increase the risk of maternal mortality in pregnant women. Nearly 600,000 women die from childbirth-related causes each year, the vast majority of them from complications which could be reduced through better nutrition, such as vitamin A.


    Iron

    Iron deficiency, and specifically iron deficiency anemia, is one of the most severe and important nutritional deficiencies in the world. Preschool children and women of reproductive age are at highest risk. As many as 4?5 billion people, 66?80% of the world's population, may be iron deficient and approximately 2 billion people, more than 30% of the world's population, are anemic. It is estimated that more than half of the pregnant women in developing countries are anemic.

    * Iron deficiency impairs the cognitive development of children through to adolescence.

    * Iron deficiency damages immune mechanisms, and is associated with increased morbidity rates.

    * Iron deficiency impairs physical work capacity in men and women by up to 30%.

    * Iron deficiency during pregnancy is associated with multiple adverse outcomes for both mother and infant, including increased risk of sepsis, maternal mortality, perinatal mortality, and low birth weight.

    Iron deficiency and anemia reduce learning ability and the work capacity of individuals and entire populations, bringing serious economic consequences and obstacles to national development.


    Iodine

    The problem of iodine deficiency is especially serious for pregnant women and young children. During pregnancy, even a mild deficiency of iodine can reduce brain development of the fetus limiting the intellectual ability of an individual for life.

    * Iodine deficiency can cause severe mental and physical retardation, known as cretinism.

    * Iodine deficiency in chronic form, can cause goiter (a disorder characterized by swelling of the thyroid gland) in both adults and children.

    * Iodine deficiency most commonly, impedes fetal brain development. At the population level, the consequence of iodine deficiency is a 10?15% lower average intellectual quotient (IQ), which affects the social and economic development of both communities and nations.


    The World Bank has estimated that, combined with vitamin A deficiency and iron deficiency, iodine deficiency may lower the economic wealth of a nation by as much as 5% every year.


    Folic Acid

    An estimated 300,000 children are born each year with spina bifida and anencephaly, which are severe neural tube defects. Approximately 75%, 225,000, of these affected births could be prevented through increased consumption of synthetic folic acid by all women of reproductive age.

    * Folic acid can help prevent birth defects of the brain (anencephaly) and the spinal cord (spina bifida) called neural tube defects.

    * Folic acid can help prevent anemia.

    * Folic acid can possibly help prevent breast cancer, colon cancer and heart disease

  • #2
    Re: Micronutrient Facts

    British Journal of Nutrition (2007), 98, Suppl. 1, S24–S28

    Iron, copper and immunocompetence

    Carlos Munoz 1*, Ernesto Rios 2, Jorge Olivos 3, Oscar Brunser 1 and Manuel Olivares 1

    Santiago, Chile

    British Journal of Nutrition Microminerals including copper and iron are essential to immunity and health in human beings. The development of powerful tools in analytical cell biology and molecular genetics has facilitated efforts to identify specific cellular and molecular functions of trace elements in the maturation, activation and functions of host defence mechanisms. Selected recent reports about the role of copper and iron nutrition on immune functions are critically analysed here. Effects of trace element supplementation on infectious morbidity are also reviewed. While micromineral deficiencies, in general, may have widespread effects on nearly all components of immune response, these effects can be reversed by supplementation. However, the conflicting effects of iron deficiency and iron supplementation in vitro on the defensive systems reveals the urgent need for further additional information on the in vivo situation. In the elderly, vaccination against respiratory infections is likely to protect only 30– 70 % of the population. However, it may be possible to modulate immune function and ultimately reduce the severity of infections through micronutrient supplementation. Thus, microminerals contribute to the maintenance of the balance between immunity and health in humans.

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