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Genotoxicity and carcinogenicity of ivermectin and amoxicillin in vivo systems

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  • Genotoxicity and carcinogenicity of ivermectin and amoxicillin in vivo systems

    https://www.sciencedirect.com/scienc...82668918302175

    Genotoxicity and carcinogenicity of ivermectin and amoxicillin in vivo systems

    Author: Francielle Aparecida de Sousa,Cássio Resende de Morais,Jéssica Soares Vieira,Lavínia Sales Maranho,Francielli Lara Machado,Samanta Pereira,Lilian Cristina Barbosa,Humberto Eustáquio Coelho,Carlos Fernando Campos,Ana Maria Bonetti
    Publication: Environmental Toxicology and Pharmacology
    Publisher:Elsevier
    Date:August 2019

    Highlights


    •Ivermectin showed genotoxic and carcinogenic potential in Tradescantia pallida and Drosophila melanogaster.
    •Amoxicillin did not present genotoxic and carcinogenic potential.
    D. melanogaster and T. pallida are excellent model organisms for the screening of mutagenic xenobiotics.



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