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A security guard wearing respirator stands on duty at Donghu Hospital in Shenzhen, Guangdong province June 13, 2006. The suspected bird flu patient is undergoing treatment at the hospital. [newsphoto]China has just successfully developed three kinds of new avian influenza vaccines and a new technology on diagnosing avian influenza, according to sources with the Chinese Ministry of Agriculture on Wednesday.
The ministry said the three new vaccines, if used together, can "offer a solid technical guarantee for the Chinese government to effectively control the highly pathogenic avian influenza."
The new types, H5N1 mark inactivated vaccine, Codon optimized H5 avian influenza Ha gene DNA vaccine, and Recombinant influenza Ha subunit vaccine, were all developed by the National Avian Influenza Reference Laboratory, said the ministry.
Professor Chen Hualan, director of the National Avian Influenza Reference Laboratory, told Xinhua that though the three new vaccines have not yet put into production, they have been proved very effective in prevention and control of the avian influenza epidemic.
According to the ministry, China led the world in developing the H5N1 mark inactivated vaccine. This vaccine will allow the serological differentiation of vaccinated from infected chickens, which has been proved with high efficiency and safety through lab tests.
The newly developed Rapid diagnostic strip for detecting H5 avian influenza virus can detect out H5 subtype avian influenza virus with only 10-plus minutes, which will be of great importance for a rapid control of bird flu epidemic in China, said the ministry.
China promoted the use of its first vaccine product--avian influenza inactivated vaccine (H5N2 subtype ) in 2004 when the highly pathogenic avian broke out in the country.
Based on the first vaccine proved effective in containing the bird flu epidemic, scientists at the National Lab, using a technique called reverse genetics, altered the genome sequence of the virus and constructed three other vaccines in succession since the year 2004.
According to Prof. Chen, the three vaccines included the reverse genetics inactivated vaccine (H5N1), H5N1 recombinant fowl pox vaccine, and recombinant bivalent avian influenza-Newcastle disease live vaccine.
The Ministry of Agriculture approved the production of the reverse genetics inactivated vaccine (H5N1) and the H5N1 recombinant fowlpox vaccine in 2004.
The ministry said the reverse genetics inactivated vaccine (H5N1), the currently most advanced vaccine in its kind, "cut a key link in the transmission chain of the highly pathogenic avian influenza among water fowl". The vaccine has been widely used in China and some foreign countries like Vietnam.
The recombinant bivalent avian influenza-Newcastle disease live vaccine, one completely researched and developed by Chinese scientists at the end of 2005, is also a breakthrough in the world, which has already been put into production.
Currently, these vaccines under production have been exported to many countries, including Vietnam, Indonesia, Mongolia, Egypt and Iraq.
According to the ministry, China's National Reference Lab on Foot-and-Mouth Disease has also finished the lab study on a new kind of Foot-and-Mouth Disease vaccine, which is believed more safe and effective than the existing vaccines through lab tests.
China has reported 18 cases of human infection of bird flu since last November with 12 fatalities. The last case was confirmed on April 27.
Globally, 225 human infections, including 128 deaths, have been recorded by the World Health Organization (WHO), according to the WHO website.
The central government is strengthening prevention and control of bird flu although no new human cases have been confirmed for more than a month, a health official said Monday.
China's Ministry of Agriculture also issued an emergency order Monday for local governments to tighten controls over poultry stocks to prevent bird flu contamination by migratory birds.
And the ministry also started a national check this week on the implementation of the immunization policy in most areas of the country. About 31 inspection groups have arrived at the rural farms to check the effects of immunization.
The Chinese government believed the immunization measures, carried out properly, will lower the possibility of a large-scale outbreak in the country.
The Chinese government is attaching more attention on scientific research about avian influenza vaccines. Nine companies have been appointed by the Ministry of Agriculture to produce the vaccines.
Editor: Yan
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China Develops Three New Avian Influenza Vaccines
</TD></TR><TR><TD class=dtime>Latest Updated by 2006-06-15 08:48:06
</TD></TR><TR><TD class=dc><TABLE class=rlblock cellSpacing=0 cellPadding=0 width=200 align=right border=0><TBODY><TR><TD vAlign=top align=middle><TABLE class=spet cellSpacing=2 cellPadding=0 width="100%" border=0><TBODY><TR><TD class=ct bgColor=#d36834 height=18>Related News</TD></TR></TBODY></TABLE><TABLE class=rlnewsblock cellSpacing=0 cellPadding=0 width="99%" border=0><TBODY><TR><TD class=newsline3>China reports new bird flu case</TD></TR><TR><TD class=newsline3>WHO center set up in GD to fight Bird flu</TD></TR><TR><TD class=newsline3>Shenzhen man may get infected with bird flu</TD></TR><TR><TD class=newsline3>China-made Tamiflu Approved for Production</TD></TR><TR><TD class=newsline3>China issues emergency bird flu control order</TD></TR></TBODY></TABLE><TABLE class=spet cellSpacing=2 cellPadding=0 width="100%" border=0><TBODY><TR><TD class=ct bgColor=#d36834 height=18>China </TD></TR></TBODY></TABLE><TABLE class=rlnewsblock cellSpacing=0 cellPadding=0 width="99%" border=0><TBODY><TR><TD class=newsline3>China Develops Three New Avian Influenza Vaccines</TD></TR><TR><TD class=newsline3>China to release films to mark CPC's 85th birthday</TD></TR><TR><TD class=newsline3>Chinese president foresees better strategic partnership with Kazakhstan</TD></TR></TBODY></TABLE></TD></TR></TBODY></TABLE>A security guard wearing respirator stands on duty at Donghu Hospital in Shenzhen, Guangdong province June 13, 2006. The suspected bird flu patient is undergoing treatment at the hospital. [newsphoto]
The ministry said the three new vaccines, if used together, can "offer a solid technical guarantee for the Chinese government to effectively control the highly pathogenic avian influenza."
The new types, H5N1 mark inactivated vaccine, Codon optimized H5 avian influenza Ha gene DNA vaccine, and Recombinant influenza Ha subunit vaccine, were all developed by the National Avian Influenza Reference Laboratory, said the ministry.
Professor Chen Hualan, director of the National Avian Influenza Reference Laboratory, told Xinhua that though the three new vaccines have not yet put into production, they have been proved very effective in prevention and control of the avian influenza epidemic.
According to the ministry, China led the world in developing the H5N1 mark inactivated vaccine. This vaccine will allow the serological differentiation of vaccinated from infected chickens, which has been proved with high efficiency and safety through lab tests.
The newly developed Rapid diagnostic strip for detecting H5 avian influenza virus can detect out H5 subtype avian influenza virus with only 10-plus minutes, which will be of great importance for a rapid control of bird flu epidemic in China, said the ministry.
China promoted the use of its first vaccine product--avian influenza inactivated vaccine (H5N2 subtype ) in 2004 when the highly pathogenic avian broke out in the country.
Based on the first vaccine proved effective in containing the bird flu epidemic, scientists at the National Lab, using a technique called reverse genetics, altered the genome sequence of the virus and constructed three other vaccines in succession since the year 2004.
According to Prof. Chen, the three vaccines included the reverse genetics inactivated vaccine (H5N1), H5N1 recombinant fowl pox vaccine, and recombinant bivalent avian influenza-Newcastle disease live vaccine.
The Ministry of Agriculture approved the production of the reverse genetics inactivated vaccine (H5N1) and the H5N1 recombinant fowlpox vaccine in 2004.
The ministry said the reverse genetics inactivated vaccine (H5N1), the currently most advanced vaccine in its kind, "cut a key link in the transmission chain of the highly pathogenic avian influenza among water fowl". The vaccine has been widely used in China and some foreign countries like Vietnam.
The recombinant bivalent avian influenza-Newcastle disease live vaccine, one completely researched and developed by Chinese scientists at the end of 2005, is also a breakthrough in the world, which has already been put into production.
Currently, these vaccines under production have been exported to many countries, including Vietnam, Indonesia, Mongolia, Egypt and Iraq.
According to the ministry, China's National Reference Lab on Foot-and-Mouth Disease has also finished the lab study on a new kind of Foot-and-Mouth Disease vaccine, which is believed more safe and effective than the existing vaccines through lab tests.
China has reported 18 cases of human infection of bird flu since last November with 12 fatalities. The last case was confirmed on April 27.
Globally, 225 human infections, including 128 deaths, have been recorded by the World Health Organization (WHO), according to the WHO website.
The central government is strengthening prevention and control of bird flu although no new human cases have been confirmed for more than a month, a health official said Monday.
China's Ministry of Agriculture also issued an emergency order Monday for local governments to tighten controls over poultry stocks to prevent bird flu contamination by migratory birds.
And the ministry also started a national check this week on the implementation of the immunization policy in most areas of the country. About 31 inspection groups have arrived at the rural farms to check the effects of immunization.
The Chinese government believed the immunization measures, carried out properly, will lower the possibility of a large-scale outbreak in the country.
The Chinese government is attaching more attention on scientific research about avian influenza vaccines. Nine companies have been appointed by the Ministry of Agriculture to produce the vaccines.
Editor: Yan
</TD></TR></TBODY></TABLE>