H5N2 Low pathogenic avian influenza (poultry), Chinese Taipei (WAHID Interface - OIE World Animal Health Information Database, 4/02/10, edited)

[Giuseppe]

[Source: OIE, <cite cite="http://www.oie.int/wahis/public.php?page=single_report&pop=1&reportid=9108" >WAHID Interface - OIE World Animal Health Information Database</cite>. Edited.]

Low pathogenic avian influenza (poultry), Chinese Taipei

Information received on 02/04/2010 from Dr Kwo-Ching Huang, Chief Veterinary Officer and Deputy Director General, , Bureau of Animal and Plant Health Inspection and Quarantine Council of agriculture, Executive Yuan , Taipei, Chinese Taipei

• Summary
  • Report type Follow-up report No. 3 (Final report)
  • Start date 09/01/2010
  • Date of first confirmation of the event 21/01/2010
  • Report date 02/04/2010
  • Date submitted to OIE 02/04/2010
  • Date event resolved 02/04/2010
  • Reason for notification Reoccurrence of a listed disease
  • Date of previous occurrence 14/11/2008
  • Manifestation of disease Clinical disease
  • Causal agent Low pathogenic avian influenza virus
  • Serotype H5N2
  • Nature of diagnosis Clinical, Laboratory (advanced)
  • This event pertains to a defined zone within the country
  • Related reports
    • Immediate notification (21/01/2010)
    • Follow-up report No. 1 (11/02/2010)
    • Follow-up report No. 2 (04/03/2010)
    • Follow-up report No. 3 (02/04/2010)

• Outbreaks
  • There are no new outbreaks in this report

• Epidemiology
  • Source of the outbreak(s) or origin of infection
    • Unknown or inconclusive

• Epidemiological comments
  • The summary of the event including three H5N2 LPAI outbreaks, reported respectively on 21 January, 10 February and 4 March 2010, is as follows:
    1. The samples of the first outbreak of H5N2 LPAI were collected on 17 January 2010, from a broiler farm with 49,000 chickens, and the virus was isolated on 21 January 2010. Based on the sequence of HA0 cleavage site (REKR*GLF) on 22 January 2010, and IVPI of the isolate 0.0, determined on 3 February 2010, the virus was classified as LPAIV. The movement restriction was effected on 21 January 2010. Second sampling of the first index farm was done on 26 January 2010, and the negative result of virus isolation was obtained on 5 February 2010. The healthy chickens were kept for slaughter for consumption, and the animals in index farm were depopulated completely on 10 March 2010. Cleaning and disinfection of the index farm was completed at the end of March under the supervision of prefectural livestock disease control centre. Based on the clinical observations and laboratory tests, including gross lesions and microbiological examinations, the culls and deaths of the animals on the index farm was mainly caused by the co-infections of chicken with infectious anaemia, mycoplasma and avian infectious bronchitis.
    2. The second outbreak, occurred in a layer farm approximately 1km away from the first index farm, was detected by the intensified surveillance of the 3-km-radius area around the first index farm. The clinical investigation of the farm showed the animals were in health condition and the daily mortality was 0.035%, which is considered being normal. From the second farm, H5N2 virus was isolated and characterized from the swab samples, collected on 27 January 2010, and determined on 8 February 2010. The IVPI of 0.0 and sequence of HA0 cleavage site (REKR*GLF) showed the virulence of the virus being low pathogenic and similar to the virus found on the first index farm. The movement restriction was imposed on 8 February 2010. The second sampling of the second farm was carried out on 22 February 2010. The negative results of RT-PCR and virus isolation were obtained on 8 March 2010. Movement ban was lifted subsequently.
    3. The third outbreak, which was reported on 4 March 2010, was also observed by the intensified surveillance of the 3-km-radius area around the first index farm. The clinical investigation of the farm also showed the animals in healthy condition and the daily mortality was 0.04%. The first samples of the third farm were collected on 5 February 2010, virus isolation was completed on 12 February 2010, and virus characterization finalized on 4 March 2010. From the clinical investigation and laboratory results, the causal virus of H5N2 would be low pathogenic. The second samples of the third farm were collected on 1 March 2010. The virus isolation of second sampling was negative whereas viral RNA specific for H5N2 by RT-PCR was detected in a flock of 130-day-old chickens. All the animals of the flock, a total of 1,425 chickens, were destroyed as a measure of precaution on 6 March 2010. The third sampling of the third farm was done on 10 March 2010. No any virus circulation was revealed by virus isolation and RT-PCR. The movement restriction has been lifted since 2 April 2010.
  • According to the aforementioned information, Chinese Taipei declares that the H5N2 avian influenza outbreaks are resolved.

• Control measures
  • Measures applied
    • Quarantine
    • Movement control inside the country
    • Screening
    • Zoning
    • Disinfection of infected premises/establishment(s)
    • Modified stamping out
    • Vaccination prohibited
    • No treatment of affected animals
  • Measures to be applied
    • No other measures

• Diagnostic test results
  • Laboratory name and type Animal Health Research Institute (National laboratory)
    • Tests and results: Species - Test - Test date - Result
      • Birds - haemagglutination inhibition test (HIT) - 08/03/2010 - Positive
      • Birds - haemagglutination inhibition test (HIT) - 18/03/2010 - Positive
      • Birds - haemagglutination inhibition test (HIT) - 23/03/2010 - Positive
      • Birds - intravenous pathogenicity index (IVPI) test - 20/02/2010 - Negative
      • Birds - reverse transcription - polymerase chain reaction (RT-PCR) - 08/03/2010 - Negative
      • Birds - reverse transcription - polymerase chain reaction (RT-PCR) - 18/03/2010 - Positive
      • Birds - reverse transcription - polymerase chain reaction (RT-PCR) - 23/03/2010 - Negative
      • Birds - virus isolation - 08/03/2010 - Negative
      • Birds - virus isolation - 18/03/2010 - Negative
      • Birds - virus isolation - 23/03/2010 - Negative
      • Birds - virus sequencing - 10/02/2010 - Positive

• Future Reporting
  • The event is resolved. No more reports will be submitted.

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[Sally Furniss]

Re: Low pathogenic avian influenza (poultry), Chinese Taipei (WAHID Interface - OIE World Animal Health Information Database, 4/02/10, edited)

Changhua from bird flu this spring, three involving hidden epidemic (video)

To March this year, Changhua were three cases of the outbreak of H5N2 bird flu, China announced the Council of Agriculture are low pathogenic, and informed the World Organization for Animal Health, but according to internal documents of the Council of Agriculture, which by the end of February bird flu, chickens intravenous pathogenicity index was 2.41, than the OIE than double the 1.2 also, there is highly pathogenic, scholars criticized the Council of Agriculture in connection hidden epidemic, is not desirable.

By the end of February this year, Changhua outbreak of bird flu at a farm, the COA also held two diagnostic monitoring session immediately, according to minutes of meetings that the two test viruses IVPI value, that is, intravenous inoculation of chickens pathogenicity index is 2.41, compared with the OIE than double the 1.2 also, are highly pathogenic, but they claim low pathogenic Council of Agriculture, attracted academics.

Professor Lai, Sui, the government should not sham, really can make the industry informed of the alert to prevent, to avoid further spread of the Council of Agriculture BAPHIQ explained, virus detection value is 2.41, but based on clinical symptoms, mortality and 2 determination made by animal experiments, a low pathogenic.

Council of Agriculture has informed the OIE comprehensive determination and emphasized the outbreak of the farm and around 3 km of the farm, no more detectable virus, the virus spread with a low toxicity, but the academics concerned Despite the low probability of pathogen transfer of highly pathogenic very low, but no comprehensive culling of sick chickens in farms, fear will increase the risk of virus re.

http://web.pts.org.tw/php/news/pts_news/detail.php?NEENO=147772