Complete Genome Sequence of a Novel Variant Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Strain: Evidence for Recombination between Vaccine and Wild-Type PRRSV Strains

[Emily]

http://jvi.asm.org/content/86/17/9543.short

Complete Genome Sequence of a Novel Variant Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) Strain: Evidence for Recombination between Vaccine and Wild-Type PRRSV Strains

Lu Wenhuia,
Wei Zhongyana,
Zhang Guanquna,
Li Zhilib,
Ma JingYuna,
Xie Qingmeia,
Sun Baolia and
Bi Yingzuoa,b

+ Author Affiliations

aCollege of Animal Science, South China Agricultural University, Tianhe District, Guangzhou, Guangdong, People's Republic of China
bCollege of Veterinary Medicine, South China Agricultural University, Tianhe District, Guangzhou, Guangdong, People's Republic of China

ABSTRACT

Porcine reproductive and respiratory syndrome virus (PRRSV) is the etiologic agent of porcine reproductive and respiratory syndrome (PRRS), which can evolve continuously by random mutation or intragenic recombination. Here we report the complete genomic sequence of a PRRSV variant with nucleotide acid deletions and insertions in the nonstructural protein 2 (nsp2) gene and a possible recombination event between a modified live virus (MLV) vaccine strain and a prototype Chinese field strain.
FOOTNOTES
Received 29 May 2012.
Accepted 14 June 2012.
Copyright ? 2012, American Society for Microbiology. All Rights Reserved.