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EGYPT - Human horse flu case (?)

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  • EGYPT - Human horse flu case (?)

    Egyptians concerned about horse influenza. Do people get horse flu? This article seems to say that someone (in Egypt) has contracted horse flu....

    Machine-translated from Arabic:

    The horse influenza threatens the Egyptians
    The virus moves to the human and a danger to the immunity decrease diseases

    July 21, 2007

    Magdi Abdul Rahman wrote:

    Parliament members surprised the government by the file of the more hotness and an excitement where the deputies Mohsen Radi, Ahmed Abdul Qader and Ahmed Aboubrka offered urgent questions to the mountain all of Dr. Hatem the Minister of Health and engineer Amin Abaza the Minister of Agriculture revealed in it a condition from the panic that injured the citizens after the declaration of the discovery of the horse influenza.

    The deputies warned of the easing with the appearance of epidemic that was confirmed its moving from the horse to the human being.

    The deputies demanded from the government offering urgent reports that reveals in it the measures nature that was taken for the resistance to the disease that spreads in Saudi Arabia and the United Arab Emirates and that Egypt participates in the competitions of horse in these countries.

    The deputies confirmed that the disease leads to the death of horse and despite that the virus moves quickly to the human nevertheless it is not from the killing viruses nevertheless it represents a great seriousness to persons injured by the decrease diseases of immunity and the kidney failure and the hepatic ones.

    They called on the committee of agriculture and health for holding a common emergency meeting for the discussion of the epidemic crisis and the probabilities of its moving to the sectors of the animal wealth and he is what threatens the animal production in Egypt.

    http://www.algomhuria.net.eg/almessa...t/detail07.asp
    ...when you have eliminated the impossible, whatever remains, however improbable, must be the truth. - Sherlock Holmes

  • #2
    Re: EGYPT - Human horse flu case (?)

    Originally posted by Theresa42 View Post
    Egyptians concerned about horse influenza. Do people get horse flu? This article seems to say that someone (in Egypt) has contracted horse flu....
    I had no idea, but a quick Google search yielded this old study case:
    http://www.cdc.gov/ncidod/eid/vol1no1/downmurr.htm
    EID Volume 1, Number 1, January-March 1995

    A Novel Morbillivirus Pneumonia of Horses and its Transmission to Humans, Keith Murray, Russell Rogers, Linda Selvey, Paul Selleck, Alex Hyatt, Allan Gould, Laurie Gleeson, Peter Hooper, Harvey Westbury

    AND this:
    AND this:
    http://en.wikipedia.org/wiki/Borna_virus

    Borna Virus

    The causative agent of Borna disease, Borna disease virus (BDV) is a neurotropic virus and is the sole member of the Bornaviridae family within the Mononegavirales order. It has the smallest genome (8.9 kilobases) of any Mononegavirales species and is unique within that order in its ability to replicate within the host cell nucleus.
    Although the virus is seen mainly as the causative agent of borna disease in horses and other animals, recent findings have implicated the borna virus in some human neurological and psychiatric conditions including bipolar disorder.
    "In the beginning of change, the patriot is a scarce man (or woman https://flutrackers.com/forum/core/i...ilies/wink.png), and brave, and hated and scorned. When his cause succeeds, the timid join him, for it then costs nothing to be a patriot."- Mark TwainReason obeys itself; and ignorance submits to whatever is dictated to it. -Thomas Paine

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    • #3
      Re: EGYPT - Human horse flu case (?)

      Horse Influenza - H7N7

      H7N7

      From Wikipedia, the free encyclopedia


      H7N7 is a subtype of the species Influenza A virus (sometimes called bird flu virus). Highly pathogenic strains (HPAI) and low pathogenic strains (LPAI) exist. H7N7 can infect humans, birds, pigs, seals, and horses in the wild; and has infected mice in laboratory studies. This unusual zoonotic potential represents a pandemic threat.


      In 2003 in the Netherlands 89 people were confirmed to have the H7N7 influenza virus infection following an outbreak in poultry on several farms.


      One death was recorded. <sup id="_ref-0" class="reference">[1]</sup> Antibodies were found in over half of 500 persons tested according to the final official report by the Dutch government:
      <dl><dd>As at least 50% of the people exposed to infected poultry had H7 antibodies detectable with the modified assay, it was estimated that avian influenza A/H7N7 virus infection occurred in at least 1000, and perhaps as many as 2000 people. The seroprevalence of H7 antibodies in people without contact with infected poultry, but with close household contact to an infected poultry worker, was 59%. This suggests that the population at risk for avian influenza was not limited to those with direct contact to infected poultry, and that person to person transmission may have occurred on a large scale. <sup id="_ref-1" class="reference">[2]</sup> Final analysis of Dutch avian influenza outbreaks reveals much higher levels of transmission to humans than previously thought <sup id="_ref-2" class="reference">[3]</sup>.</dd></dl> In August 2006, low pathogenic H7N7 was found during routine testing at a poultry farm in Voorthuizen in the central Netherlands. As a precautionary measure, 25,000 chickens were culled from Voorthuizen and surrounding farms.<sup id="_ref-3" class="reference">[4]</sup>
      "In the beginning of change, the patriot is a scarce man (or woman https://flutrackers.com/forum/core/i...ilies/wink.png), and brave, and hated and scorned. When his cause succeeds, the timid join him, for it then costs nothing to be a patriot."- Mark TwainReason obeys itself; and ignorance submits to whatever is dictated to it. -Thomas Paine

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      • #4
        Re: EGYPT - Human horse flu case (?)

        Sounds more like concern over a hypothetical scenario rather than an actual case...

        Google-translated from Arabic:

        The decision to sell Banque Du Caire and the government is considering the privatization plan of construction companies
        Warnings of influenza horses .. The deputies holding the government responsible for poverty
        Egyptians spend hundreds of millions on obscene phone messages

        July 10, 2007

        (...)

        The MP Mohammad-Brothers-Justice asked the prime minister and ministers of agriculture and health on influenza horses that have recently appeared in some Gulf countries, such as Saudi Arabia and UAE. He showed that this disease easily transmitted from animal to man [really?], adding that the greatest danger lies in the transmission of the human being to another. He warned against complacency in dealing with the disease so as not to be surprised by the government also surprised disease avian influenza before, and wasting millions of dollars in order to contain the disease without the benefit. The deputy wondered about preventive measures taken by the government to prevent people from the threat of avian horses, especially Egypt participates in competitions horses in the Gulf?!

        (...)

        http://www.alshaab.com/news.php?i=7320
        ...when you have eliminated the impossible, whatever remains, however improbable, must be the truth. - Sherlock Holmes

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        • #5
          Re: EGYPT - Human horse flu case (?)

          Originally posted by Niko View Post
          Horse Influenza - H7N7

          H7N7

          From Wikipedia, the free encyclopedia
          Thanks, Niko!

          Sounds like H3N8 is also "horse flu":
          Originally posted by Wikipedia
          H3N8 is a subtype of the species Influenza A virus (sometimes called bird flu virus). H3N8 is now endemic in birds, horses and dogs.

          H3N8 is suspected of causing a human pandemic in either 1889 or 1900. Sources differ; some say the 1889 pandemic was caused H2N2. The experts also differ on exactly how sure we can be that either were involved.[1]

          It was the subtype that was responsible for over one-forth of the flu infections in wild ducks in a 1997 study.[2]

          http://en.wikipedia.org/wiki/H3N8
          Wonder which one -- H7N7 or H3N8 (or another one?) -- they're worried about in Egypt?
          ...when you have eliminated the impossible, whatever remains, however improbable, must be the truth. - Sherlock Holmes

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          • #6
            Re: EGYPT - Human horse flu case (?)

            see earlier post about Morbillivirus in animals and humans at
            http://www.flutrackers.com/forum/sho...ighlight=whale

            It's a subset of the PARAMYXOVIRIDAE subfamily.

            .
            "The next major advancement in the health of American people will be determined by what the individual is willing to do for himself"-- John Knowles, Former President of the Rockefeller Foundation

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            • #7
              Re: EGYPT - Human horse flu case (?)

              Originally posted by Theresa42 View Post
              Thanks, Niko!

              Sounds like H3N8 is also "horse flu":Wonder which one -- H7N7 or H3N8 (or another one?) -- they're worried about in Egypt?
              Although both H3 (as in H3N2) and H7 (as in H7N2, H7N3, H7N7) serotypes have been shown to cause human infections, H3N8 has not been reported in humans, and H7N7 in humans has been limited to the outbreak in the Netherlands (and reports of equine influenza have been limited to H3N8 and H7N7).

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              • #8
                Re: EGYPT - Human horse flu case (?)

                I believe the migratory birds found (in ALaska) to be carrying internal segments from Asian mammalian H5N1 were those with external H3N8.

                .
                "The next major advancement in the health of American people will be determined by what the individual is willing to do for himself"-- John Knowles, Former President of the Rockefeller Foundation

                Comment


                • #9
                  Re: EGYPT - Human horse flu case (?)

                  Originally posted by niman View Post
                  Although both H3 (as in H3N2) and H7 (as in H7N2, H7N3, H7N7) serotypes have been shown to cause human infections, H3N8 has not been reported in humans, and H7N7 in humans has been limited to the outbreak in the Netherlands (and reports of equine influenza have been limited to H3N8 and H7N7).
                  "The two major strains known to cause disease in equids are H7N7 (A/eq/Prague/56[H7N7], type A influenza, equine, first isolated in Czechoslovakia in 1956) and H3N8 (A/eq/Miami/2/63[H3N8], type A influenza, equine, first isolated in Miami, strain 2, isolated in 1963). The two subtypes are immunologically distinct. Sublineages of the two major strains (e.g., A/eq/Newmarket/2/93[H3N8], A/eq/Kentucky/92[N3H8]) have emerged due to antigenic shift (reassortment of the genome resulting in genetic alteration) and antigenic drift (point mutations in the genetic code causing minor alterations in the H and N glycoproteins)."

                  Backgrounder on equine influenza at:
                  http://www.avma.org/reference/backgr...quine_bgnd.pdf

                  Intriguing abstract- can't access the whole article yet..

                  Studies of Antibodies to 1956 and 1963 Equine Influenza Viruses in Horses and Man1
                  Elva Minuse, James L. McQueen2, Fred M. Davenport and Thomas Francis, Jr.
                  From the Department of Epidemiology and Virus Laboratory, School of Public Health, University of Michigan, Ann Arbor, Michigan

                  Abstract

                  Fourteen of 30 horses with pre-existing hemagglutination inhibition (HI) antibodies to A/Equine-1/Prague/1/56 virus exhibited 4-fold or greater rise in titer after infection with the A/Equine-2/63 agent. These findings give further evidence of shared viral antigens among the two families of Type A/Equine virus.

                  HI and neutralizing antibodies to A/Equine-2/63 virus were found in human serum from individuals born between 1870 and 1900. Persons born about 1880 to 1890, however, exhibited higher levels and higher frequencies of antibody than did younger or older individuals. The results suggest a relationship between hemagglutination (HA) antigens of the 1963 equine strains and a virus formerly prevalent in man.

                  http://www.jimmunol.org/cgi/content/abstract/94/4/563



                  Another interesting abstract with full article requiring a subscription.

                  J. D. TODD 2, FLORENCE S. LIEF and DANIEL COHEN. EXPERIMENTAL INFECTION OF PONIES WITH THE HONG KONG VARIANT OF HUMAN INFLUENZA VIRUS American Journal of Epidemiology Vol. 92, No. 5: 330-336

                  Eight ponies exposed intranasally to a Hong Kong (HK) influenza virus (A2/Phila/101/68) of high titer became infected and shed virus in their nasal secretions for as long as 7 days after exposure. All responded with significant rises in neutralizing and CF serum antibodies to both HK and A/Equi-2 viruses, neutralizing antibody titers against the equine-2 strain of virus being higher than those directed against the infecting strain. One pony also developed a significant rise of antibody against A/Equi-1 virus. Most antibody responses were secondary in nature, indicating a previous encounter with antigens present in the infecting HK strain. None of the ponies became ill, although the investigator who administered the virus developed a typical influenza-like illness within 72 hours. Virus was not recovered from either of two control ponies, and they developed no increase in serum antibody. The results clearly confirm that horses can become infected experimentally with the HK variant of human influenza virus. Antibody responses were consistent with the known antigenic relationship between the newest human type A strain and equine-2 virus.

                  http://aje.oxfordjournals.org/cgi/co...tract/92/5/330
                  Separate the wheat from the chaff

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