Open Forum Infect Dis . Viral Load Among Vaccinated and Unvaccinated, Asymptomatic and Symptomatic Persons Infected With the SARS-CoV-2 Delta Variant

[tetano]

Open Forum Infect Dis


. 2022 Mar 17;9(5):ofac135.
doi: 10.1093/ofid/ofac135. eCollection 2022 May.
Viral Load Among Vaccinated and Unvaccinated, Asymptomatic and Symptomatic Persons Infected With the SARS-CoV-2 Delta Variant


Charlotte B Acharya ¹ , John Schrom ² , Anthea M Mitchell ³ , David A Coil ¹ , Carina Marquez ^{2 4} , Susana Rojas ² , Chung Yu Wang ³ , Jamin Liu ⁵ , Genay Pilarowski ^{2 6} , Leslie Solis ¹ , Elizabeth Georgian ¹ , Sheri Belafsky ⁷ , Maya Petersen ^{2 8} , Joseph DeRisi ³ , Richard Michelmore ¹ , Diane Havlir ^{2 4}



Affiliations

• PMID: 35479304
• PMCID: PMC8992250
• DOI: 10.1093/ofid/ofac135

Abstract

We found no significant difference in cycle threshold values between vaccinated and unvaccinated persons infected with severe acute respiratory syndrome coronavirus 2 Delta, overall or stratified by symptoms. Given the substantial proportion of asymptomatic vaccine breakthrough cases with high viral levels, interventions, including masking and testing, should be considered in settings with elevated coronavirus disease 2019 transmission.

Keywords: 19; COVID; Ct value; Delta variant; SARS-CoV-2; asymptomatic testing.