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Eur Phys J Plus
. 2022;137(3):395.
doi: 10.1140/epjp/s13360-022-02603-z. Epub 2022 Mar 28.
A fractional-order mathematical model for COVID-19 outbreak with the effect of symptomatic and asymptomatic transmissions
Zeeshan Ali 1 , Faranak Rabiei 1 , Mohammad M Rashidi 2 , Touraj Khodadadi 3
Affiliations
- PMID: 35368740
- PMCID: PMC8958840
- DOI: 10.1140/epjp/s13360-022-02603-z
Abstract
The purpose of this paper is to investigate the transmission dynamics of a fractional-order mathematical model of COVID-19 including susceptible ( S
), exposed ( E ), asymptomatic infected ( I1 ), symptomatic infected ( I2 ), and recovered ( R ) classes named SEI1I2R model, using the Caputo fractional derivative. Here, SEI1I2R model describes the effect of asymptomatic and symptomatic transmissions on coronavirus disease outbreak. The existence and uniqueness of the solution are studied with the help of Schaefer- and Banach-type fixed point theorems. Sensitivity analysis of the model in terms of the variance of each parameter is examined, and the basic reproduction number (R0) to discuss the local stability at two equilibrium points is proposed. Using the Routh-Hurwitz criterion of stability, it is found that the disease-free equilibrium will be stable for R0<1 whereas the endemic equilibrium becomes stable for R0>1 and unstable otherwise. Moreover, the numerical simulations for various values of fractional-order are carried out with the help of the fractional Euler method. The numerical results show that asymptomatic transmission has a lower impact on the disease outbreak rather than symptomatic transmission. Finally, the simulated graph of total infected population by proposed model here is compared with the real data of second-wave infected population of COVID-19 outbreak in India.