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Emerg Infect Dis
. 2021 Feb 18;27(4).
doi: 10.3201/eid2704.204576. Online ahead of print.
Analysis of Asymptomatic and Presymptomatic Transmission in SARS-CoV-2 Outbreak, Germany, 2020
Jennifer K Bender, Michael Brandl, Michael H?hle, Udo Buchholz, Nadine Zeitlmann
- PMID: 33600301
- DOI: 10.3201/eid2704.204576
Abstract
We determined secondary attack rates (SAR) among close contacts of 59 asymptomatic and symptomatic coronavirus disease case-patients by presymptomatic and symptomatic exposure. We observed no transmission from asymptomatic case-patients and highest SAR through presymptomatic exposure. Rapid quarantine of close contacts with or without symptoms is needed to prevent presymptomatic transmission.
Keywords: COVID-19; Germany; SARS-CoV-2; asymptomatic diseases; contact; coronavirus disease; disease transmission; epidemiology; infectious; respiratory infections; risk; severe acute respiratory syndrome coronavirus 2; viruses; zoonoses.