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Emergence in late 2020 of multiple lineages of SARS-CoV-2 Spike protein variants affecting amino acid position 677
View ORCID ProfileEmma B Hodcroft, View ORCID ProfileDaryl B Domman, Daniel J Snyder, View ORCID ProfileKasopefoluwa Oguntuyo, View ORCID ProfileMaarten Van Diest, Kenneth H Densmore, Kurt C Schwalm, Jon Femling, Jennifer L Carroll, Rona S Scott, Martha M Whyte, Michael D Edwards, View ORCID ProfileNoah C Hull, View ORCID ProfileChristopher G Kevil, John A Vanchiere, Benhur Lee, View ORCID ProfileDarrell L Dinwiddie, View ORCID ProfileVaughn S Cooper, View ORCID ProfileJeremy P Kamil
doi: https://doi.org/10.1101/2021.02.12.21251658
7 US variants found; variants are related to each other; identified as Q677P
...Here, we describe evidence from two independent SARS-CoV-2 genomic surveillance programs in Louisiana and New Mexico that each detected the rise of S variants affecting position 677 in the later months of 2020. We further provide phylogenetic analyses that identify six independent Q677H sub-lineages and one Q677P sub-lineage that all appear to have emerged within the United States. These variants were not detected until mid-August 2020, but as of 03 Feb 2021 already account for over 2,327 of the 102,462 genomes deposited to GISAID from the USA...
Emergence in late 2020 of multiple lineages of SARS-CoV-2 Spike protein variants affecting amino acid position 677
View ORCID ProfileEmma B Hodcroft, View ORCID ProfileDaryl B Domman, Daniel J Snyder, View ORCID ProfileKasopefoluwa Oguntuyo, View ORCID ProfileMaarten Van Diest, Kenneth H Densmore, Kurt C Schwalm, Jon Femling, Jennifer L Carroll, Rona S Scott, Martha M Whyte, Michael D Edwards, View ORCID ProfileNoah C Hull, View ORCID ProfileChristopher G Kevil, John A Vanchiere, Benhur Lee, View ORCID ProfileDarrell L Dinwiddie, View ORCID ProfileVaughn S Cooper, View ORCID ProfileJeremy P Kamil
doi: https://doi.org/10.1101/2021.02.12.21251658
7 US variants found; variants are related to each other; identified as Q677P
...Here, we describe evidence from two independent SARS-CoV-2 genomic surveillance programs in Louisiana and New Mexico that each detected the rise of S variants affecting position 677 in the later months of 2020. We further provide phylogenetic analyses that identify six independent Q677H sub-lineages and one Q677P sub-lineage that all appear to have emerged within the United States. These variants were not detected until mid-August 2020, but as of 03 Feb 2021 already account for over 2,327 of the 102,462 genomes deposited to GISAID from the USA...
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