Eur Rev Med Pharmacol Sci . Is chronic obstructive pulmonary disease an independent predictor for adverse outcomes in coronavirus disease 2019 patients?

[tetano]

Eur Rev Med Pharmacol Sci


. 2020 Nov;24(21):11421-11427.
doi: 10.26355/eurrev_202011_23635.
Is chronic obstructive pulmonary disease an independent predictor for adverse outcomes in coronavirus disease 2019 patients?


W-W Xiao ¹ , J Xu, L Shi, Y-D Wang, H-Y Yang



Affiliations

• PMID: 33215464
• DOI: 10.26355/eurrev_202011_23635

Abstract

Objective: This study aimed to investigate whether pre-existing chronic obstructive pulmonary disease (COPD) was an independent predictor for adverse outcomes in coronavirus disease 2019 (COVID-19) patients.
Materials and methods: We searched electronic databases, including PubMed, Web of Science, EMBASE, and Chinese National Knowledge Infrastructure (CNKI) to screen for eligible articles. A quantitative meta-analysis was performed on the basis of adjusted effect estimates.
Results: We observed that COPD was significantly associated with an increased risk of adverse outcomes in COVID-19 patients, which is based on 18 studies with 26,075 cases reporting adjusted effect estimates (pooled effect = 1.53, 95% confidence interval (CI): 1.29-1.8; I2 = 35.4%, random-effects model).
Conclusions: We found that pre-existing COPD was an independent risk factor for predicting the adverse outcomes in COVID-19 patients.