sharon sanders
Editor-in-Chief & President
[h=3]Braz. oral res. vol.30 no.1 S?o Paulo 2016 Epub Mar 15, 2016[/h] [h=4]http://dx.doi.org/10.1590/1807-3107BOR-2016.vol30.0046[/h]
Walter Luiz SIQUEIRA[SUP](a) [/SUP], Eduardo Buozi MOFFA[SUP](a) [/SUP], Maria Carolina Martins MUSSI[SUP](b) [/SUP], Maria Aparecida de Andrade Moreira MACHADO[SUP](c) [/SUP]
[SUP][SUP](a)[/SUP][/SUP]University of Western Ontario, Schulich School of Medicine & Dentistry, Department of Dentistry and Biochemistry, London, ON, Canada.
[SUP][SUP](b)[/SUP][/SUP] Universidade de S?o Paulo - USP, School of Dentistry, Department of Oral Pathology, S?o Paulo, SP, Brazil.
[SUP][SUP](c)[/SUP][/SUP]Universidade de S?o Paulo - USP, Bauru Dental School, Department of Pediatric Dentistry, Orthodontics and Public Health, Bauru, SP, Brazil.
snip
The proof-of-principle has been extended and we have also shown a strong correlation between 10 cytokines present in saliva and pulmonary disease, such as asthma, using a microsphere-based antibody array.[SUP]16[/SUP]Therefore, we postulate that these new high-sensitive technologies able to measure multiples salivary biomarkers simultaneously, could become clinical tools for early detection and monitoring of prognosis and treatment for other diseases, including dengue and Zika infections.[SUP]17[/SUP] Now that researchers around the world are committed to seek ways to eradicate ZIKV, all efforts in this direction should be considered. Early diagnosis using safe and non-invasive methods for ZIKV allow therapeutic measures are taken faster with less discomfort for the patient is part of this task force against this disease.
Therefore, search for a diagnostic test for ZIKA virus, as well as other viral infections as dengue and chikungunya virus in saliva is a route that should be considered.
http://www.scielo.br/scielo.php?scr...1806-83242016000100801&lng=en&nrm=iso&tlng=en
SHORT COMMUNICATION
Zika virus infection spread through saliva ? a truth or myth?Walter Luiz SIQUEIRA[SUP](a) [/SUP], Eduardo Buozi MOFFA[SUP](a) [/SUP], Maria Carolina Martins MUSSI[SUP](b) [/SUP], Maria Aparecida de Andrade Moreira MACHADO[SUP](c) [/SUP]
[SUP][SUP](a)[/SUP][/SUP]University of Western Ontario, Schulich School of Medicine & Dentistry, Department of Dentistry and Biochemistry, London, ON, Canada.
[SUP][SUP](b)[/SUP][/SUP] Universidade de S?o Paulo - USP, School of Dentistry, Department of Oral Pathology, S?o Paulo, SP, Brazil.
[SUP][SUP](c)[/SUP][/SUP]Universidade de S?o Paulo - USP, Bauru Dental School, Department of Pediatric Dentistry, Orthodontics and Public Health, Bauru, SP, Brazil.
snip
The proof-of-principle has been extended and we have also shown a strong correlation between 10 cytokines present in saliva and pulmonary disease, such as asthma, using a microsphere-based antibody array.[SUP]16[/SUP]Therefore, we postulate that these new high-sensitive technologies able to measure multiples salivary biomarkers simultaneously, could become clinical tools for early detection and monitoring of prognosis and treatment for other diseases, including dengue and Zika infections.[SUP]17[/SUP] Now that researchers around the world are committed to seek ways to eradicate ZIKV, all efforts in this direction should be considered. Early diagnosis using safe and non-invasive methods for ZIKV allow therapeutic measures are taken faster with less discomfort for the patient is part of this task force against this disease.
Therefore, search for a diagnostic test for ZIKA virus, as well as other viral infections as dengue and chikungunya virus in saliva is a route that should be considered.
http://www.scielo.br/scielo.php?scr...1806-83242016000100801&lng=en&nrm=iso&tlng=en