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Zika infections last much longer during pregnancy, monkey study shows

tetano

Editor, Senior Moderator
New research on monkeys found some good news that could have implications for humans: One infection with the Zika virus protects against future infections.
But along with good news were some troubling findings. Researchers at the University of Wisconsin at Madison and Duke University found the virus persisted in the blood of pregnant monkeys for much longer ? up to 70 days ? compared to the 10 days it lasted in males and non-pregnant female monkeys.
The prolonged infection has implications for the Zika virus in pregnant women because the virus causes microcephaly, a severe birth defect characterized by abnormally small heads and often incomplete brain development, as well as a range of other neurological abnormalities. The research was published Tuesday in the journal Nature Communications.

https://www.washingtonpost.com/news...h-longer-during-pregnancy-monkey-study-shows/
 
Zika tests on pregnant monkeys suggest disease could be carried by humans for up to 70 days

Macaques develop Zika resistance after initial infection but pregnant monkeys carry virus for longer.

L?a Surugue By L?a Surugue
June 29, 2016 16:19 BST
...
The expectant females were only cleared of the virus 30-70 days after first contracting the infection. Therefore it is a possibility that the virus could stay much longer in the blood of pregnant women than in the blood of men and other women.

One possible explanation for the persistence of the virus during pregnancy is that the immune systems of mothers-to-be are weaker, and simply aren't able to clear the virus as quickly.

"The other, more provocative hypothesis is that it's indicative of infection of the foetus, and what we're observing in the maternal bloodstream is the shedding of the virus by the foetus back into the mother's bloodstream," says O'Connor. "If that happens to be the case, it would suggest that there is a prolonged infection of the foetus that lasts much longer than the infection of the mother."
...
http://www.ibtimes.co.uk/zika-tests-shows-virus-survives-70-days-pregnant-macaque-monkeys-1568077
 
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