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Zhonghua Liu Xing Bing Xue Za Zhi. Study on transmission dynamic of 15 clusters of coronavirus disease 2019 cases in Ningbo

tetano

Editor, Senior Moderator
Zhonghua Liu Xing Bing Xue Za Zhi. 2020 May 13;41(0):E066. doi: 10.3760/cma.j.cn112338-20200330-00466. [Epub ahead of print]
[Study on transmission dynamic of 15 clusters of coronavirus disease 2019 cases in Ningbo].


[Article in Chinese; Abstract available in Chinese from the publisher]

Pan XX[SUP]1[/SUP], Chen Y[SUP]1[/SUP], Wang AH[SUP]1[/SUP], Wang JM[SUP]1[/SUP], Ye LX[SUP]1[/SUP], Gu SH[SUP]1[/SUP], Fang T[SUP]1[/SUP], Xu GZ[SUP]1[/SUP].

Author information




Abstract

in English, Chinese
Objective: To describe the basic characteristics of clusters of coronavirus diseases 2019 (COVID-19) cases in Ningbo, Zhejiang province, and evaluate the generation time (Tg) and basic reproduction number (R(0)) of COVID-19. Methods: The basic information and onset times of the clusters of COVID-19 cases in Ningbo were investigated, the inter-generational interval of the cases were fitted by using gamma distribution, and the R(0) was calculated based on the SEIR model. Results: In the 15 clusters of COVID-19 cases, a total of 52 confirmed cases, 5 cases of nucleic acid- positive asymptomatic cases. The cases occurred from January 23 to February 4, the cases were mainly women. The incubation period was (6.11?3.38) days, and the median was 5 days. The Tg was (6.93?3.70) days. There were no significant differences in Tg between age group <60 years and age group 60 years and above, and between men and women (P=0.551). According to the Tg calculated in this paper, the R(0) of COVID-19 in Ningbo was 3.06 (95%CI: 2.64 - 3.51); according to the reported case transmission interval of 7.5 days in the literature, the R(0) was 3.32 (95%CI: 2.51-9.38 ). Conclusion: There is no age and gender specific differences in the Tg of clusters of COVID-19 cases in Ningbo, and COVID-19 has high infectivity and spreading power in early phase.



KEYWORDS:

Basic regeneration number; COVID-19; Cluster; Generation time


PMID:32397699DOI:10.3760/cma.j.cn112338-20200330-00466
 
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