tetano
Editor, Senior Moderator
Zhonghua Jie He He Hu Xi Za Zhi. 2020 Apr 12;43(4):337-339. doi: 10.3760/cma.j.cn112147-20200224-00167.
[Bronchoalveolar lavage fluid was used to diagnose two cases of 2019-nCoV infection].
[Article in Chinese; Abstract available in Chinese from the publisher]
Tan FR[SUP]1[/SUP], Qiu YL[SUP]1[/SUP], Xu Z[SUP]1[/SUP].
Author information
Abstract
in English, Chinese
The case reports 2 cases of novel coronavirus pneumonia diagnosed by concurrent bronchoalveolar lavage in our hospital, 1 case had a history of epidemiology, clinical symptoms and high imaging suspicion, but repeated negative throat swabs. One patient was diagnosed 2019-nCoV. Before the patient was discharged, the clinical symptoms disappeared, the chest CT showed significant improvement, and the pharynx swab was twice negative, reaching the discharge standard.We detected the ORF 1ab gene, the N gene and the nucleic acid of the new coronavirus in the broncho-alveolar lavage fluid of 2 patients. The results showed that the positive rate of bronchoalveolar lavage for detection of new coronavirus nucleic acid was high, and bronchoalveolar lavage for suspected or confirmed new coronavirus pneumonia patients with negative detection of nucleic acid in pharynx swabs but still residual lung lesions was helpful for early diagnosis, treatment and prognosis.
KEYWORDS:
2019-nCoV; Bronchoalveolar lavage fluid; Throat swab; Viral nucleic acid testing
PMID:32294816DOI:10.3760/cma.j.cn112147-20200224-00167
[Indexed for MEDLINE]
[Bronchoalveolar lavage fluid was used to diagnose two cases of 2019-nCoV infection].
[Article in Chinese; Abstract available in Chinese from the publisher]
Tan FR[SUP]1[/SUP], Qiu YL[SUP]1[/SUP], Xu Z[SUP]1[/SUP].
Author information
Abstract
in English, Chinese
The case reports 2 cases of novel coronavirus pneumonia diagnosed by concurrent bronchoalveolar lavage in our hospital, 1 case had a history of epidemiology, clinical symptoms and high imaging suspicion, but repeated negative throat swabs. One patient was diagnosed 2019-nCoV. Before the patient was discharged, the clinical symptoms disappeared, the chest CT showed significant improvement, and the pharynx swab was twice negative, reaching the discharge standard.We detected the ORF 1ab gene, the N gene and the nucleic acid of the new coronavirus in the broncho-alveolar lavage fluid of 2 patients. The results showed that the positive rate of bronchoalveolar lavage for detection of new coronavirus nucleic acid was high, and bronchoalveolar lavage for suspected or confirmed new coronavirus pneumonia patients with negative detection of nucleic acid in pharynx swabs but still residual lung lesions was helpful for early diagnosis, treatment and prognosis.
KEYWORDS:
2019-nCoV; Bronchoalveolar lavage fluid; Throat swab; Viral nucleic acid testing
PMID:32294816DOI:10.3760/cma.j.cn112147-20200224-00167
[Indexed for MEDLINE]