tetano
Editor, Senior Moderator
Zhongguo Dang Dai Er Ke Za Zhi
. 2020 Jun;22(6):578-582.
[Clinical Features of Asymptomatic or Subclinical COVID-19 in Children]
[Article in Chinese]
You-Jing Liu[SUP] 1 [/SUP], Peng Chen, Zhi-Sheng Liu, Ying Li, Hui DU, Jia-Li Xu
Affiliations
Abstract
Objective: To study the clinical features of asymptomatic or subclinical coronavirus disease 2019 (COVID-19) in children.
Methods: A retrospective analysis was performed for the clinical data of 53 children who were confirmed with asymptomatic or subclinical COVID-19, including epidemiological history, clinical typing, co-infection, time to clearance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleic acid in nasopharyngeal swabs, laboratory examination results, length of hospital stay, and treatment outcome.
Results: The children with asymptomatic or subclinical COVID-19 accounted for 30.5% (53/174) in children with COVID-19 hospitalized in the COVID-19 ward of Wuhan Children's Hospital. All cases occurred with familial aggregation. Among the 53 children, 35 (66%) had asymptomatic infection and 18 (34%) had subclinical infection. Mycoplasma infection was found in 17 children (32%). For the 53 children, the mean time to clearance of SARS-CoV-2 nucleic acid in nasopharyngeal swabs was 9?4 days. Most laboratory markers were maintained within the normal range. The mean hospital stay was 11?4 days. Lung CT of 18 children with subclinical COVID-19 showed ground-glass opacities, linear opacities, and patchy opacities, with relatively limited lesions.
Conclusions: There is a high proportion of children with asymptomatic or subclinical COVID-19 among the children with COVID-19 hospitalized in the COVID-19 ward. The transmission risk of asymptomatic or subclinical COVID-19 should be taken seriously.
. 2020 Jun;22(6):578-582.
[Clinical Features of Asymptomatic or Subclinical COVID-19 in Children]
[Article in Chinese]
You-Jing Liu[SUP] 1 [/SUP], Peng Chen, Zhi-Sheng Liu, Ying Li, Hui DU, Jia-Li Xu
Affiliations
- PMID: 32571455
Abstract
Objective: To study the clinical features of asymptomatic or subclinical coronavirus disease 2019 (COVID-19) in children.
Methods: A retrospective analysis was performed for the clinical data of 53 children who were confirmed with asymptomatic or subclinical COVID-19, including epidemiological history, clinical typing, co-infection, time to clearance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleic acid in nasopharyngeal swabs, laboratory examination results, length of hospital stay, and treatment outcome.
Results: The children with asymptomatic or subclinical COVID-19 accounted for 30.5% (53/174) in children with COVID-19 hospitalized in the COVID-19 ward of Wuhan Children's Hospital. All cases occurred with familial aggregation. Among the 53 children, 35 (66%) had asymptomatic infection and 18 (34%) had subclinical infection. Mycoplasma infection was found in 17 children (32%). For the 53 children, the mean time to clearance of SARS-CoV-2 nucleic acid in nasopharyngeal swabs was 9?4 days. Most laboratory markers were maintained within the normal range. The mean hospital stay was 11?4 days. Lung CT of 18 children with subclinical COVID-19 showed ground-glass opacities, linear opacities, and patchy opacities, with relatively limited lesions.
Conclusions: There is a high proportion of children with asymptomatic or subclinical COVID-19 among the children with COVID-19 hospitalized in the COVID-19 ward. The transmission risk of asymptomatic or subclinical COVID-19 should be taken seriously.