Zhong Nan Da Xue Xue Bao Yi Xue Ban. Clinical and CT imaging features between the first nucleic acid-negative and first nucleic acid-positive COVID-19

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Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2020 Mar 28;45(3):257-261. doi: 10.11817/j.issn.1672-7347.2020.200141.
Clinical and CT imaging features between the first nucleic acid-negative and first nucleic acid-positive COVID-19 patients.


[Article in Chinese, English; Abstract available in Chinese from the publisher]

Li S[SUP]1[/SUP], Liu J[SUP]2[/SUP], Xiong Z[SUP]2[/SUP], Luo W[SUP]2[/SUP], Tang H[SUP]2,[/SUP][SUP]3[/SUP], Pend W[SUP]4[/SUP], Hu Z[SUP]5[/SUP], Feng H[SUP]6[/SUP], Xie Q[SUP]6[/SUP], Liu B[SUP]7[/SUP], Liao W[SUP]2[/SUP], Zhou H[SUP]8[/SUP].

Author information




Abstract

in English, Chinese
OBJECTIVES:

To investigate the role of chest CT for the diagnostic work-up for patients with suspected infection of coronavirus disease 2019 (COVID-19).
METHODS:

The clinical data and imaging findings of the first nucleic acid-negative COVID-19 patients were analyzed and compared with the first nucleic acid-positive patients.
RESULTS:

Compared with the first nucleic acid-positive patients, the onset time of the first nucleic acid-negative patients was shorter [(3.58?2.94) d], but the diagnosis was longer [(3.92?3.66) d]. There were no significant differences in the characteristics of the clinical data and radiological findings between the 2 groups (P>0.05).
CONCLUSION:

Chest CT examination is important to avoid COVID-19 missed diagnosis due to false negative nucleic acid.



KEYWORDS:

CT imaging; coronavirus disease 2019 (COVID-19); nucleic acid-negative


PMID:32386016DOI:10.11817/j.issn.1672-7347.2020.200141
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