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Zhejiang Da Xue Xue Bao Yi Xue Ban. Pregnant women complicated with COVID-19: a clinical analysis of 3 cases

tetano

Editor, Senior Moderator
Zhejiang Da Xue Xue Bao Yi Xue Ban. 2020 May 25;49(2):240-244.
[Pregnant women complicated with COVID-19: a clinical analysis of 3 cases].


[Article in Chinese]

Chen X[SUP]1[/SUP], Li Y[SUP]1[/SUP], Wang J[SUP]1[/SUP], Cai H[SUP]2[/SUP], Cao H[SUP]3[/SUP], Sheng J[SUP]3[/SUP].

Author information




Abstract

OBJECTIVE:

To analyze the clinical characteristics and pregnancy outcomes of pregnant women complicated with coronavirus disease 2019 (COVID-19).
METHODS:

The clinical data of 3 pregnant women with COVID-19 admitted to the First Affiliated Hospital of Zhejiang University School of Medicine from January 19 to February 10, 2020 were retrospectively analyzed.
RESULTS:

There was one case in the first-trimester pregnancy (case 1), one in the second-trimester pregnancy (case 2) and one in third-trimester pregnancy (case 3). Cough, fever, fatigue, lung imaging changes were the main manifestations. The white cell count, lymphocyte percentage had no significantly changes in case 1 and case 3, while the levels of C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), IL-6 and IL-10 elevated. The lymphocyte count and lymphocyte percentage decreased and the inflammatory indicators significantly increased in case 2. All patients were treated with antiviral, antitussive, oxygen inhalation; case 3 received glucocorticoids, case 2 with severe illness received glucocorticoids and additionally gamma globulin. All three cases were cured and discharged. Case 1 with early pregnancy chose to terminate pregnancy after discharge; case 2 chose to continue pregnancy without obstetric complications; and case 3 had cesarean section delivery due to abnormal fetal heart monitoring.
CONCLUSIONS:

The report shows that COVID-19 in pregnancy women could be cured with active treatment, and the maternal and fetal outcomes can be satisfactory.



PMID:32391671
 
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