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Yonsei Med J . Clinical Characteristics of Patients Who Contracted the SARS-CoV-2 Omicron Variant from an Outbreak in a Single Hospital

tetano

Editor, Senior Moderator
Yonsei Med J


. 2022 Aug;63(8):790-793.
doi: 10.3349/ymj.2022.63.8.790.
Clinical Characteristics of Patients Who Contracted the SARS-CoV-2 Omicron Variant from an Outbreak in a Single Hospital


Yu Jin Sohn[SUP] 1 [/SUP], Pyo Jin Shin[SUP] 2 [/SUP], Won Sup Oh[SUP] 3 4 [/SUP], Eunmi Kim[SUP] 4 [/SUP], Yeojin Kim[SUP] 4 [/SUP], Young Keun Kim[SUP] 5 [/SUP]



Affiliations

Abstract

There are few studies on the severity and prognosis of patients infected with the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) omicron variant. From January 11, 2022 to January 25, 2022, 181 patients were infected with the SARS-CoV-2 omicron variant in a single hospital in Korea. The initial clinical characteristics were investigated through the COVID-19 basic investigation form. Outcomes were reviewed using medical records. The median age of the patients was 57 years (range 1-90), and 95 patients (52.5%) were male. None were re-infected with SARS-CoV-2, and 127 (70.2%) were fully vaccinated (boosted or within 6 months after second vaccination). Forty-two patients (23.2%) were asymptomatic. Among symptomatic patients, the frequency of symptoms was as follows: cough (37.0%), sore throat (33.7%), and fever (30.4%). In terms of disease severity, 168 (92.8%) patients did not require supplemental oxygen, 6 (3.3%) required low-flow oxygen, 5 (2.8%) required high-flow oxygen, and 2 (1.1%) died. Four of the five individuals who required high-flow oxygen and the two who died were not vaccinated. Most of the patients who contracted the SARS-CoV-2 omicron variant exhibited mild clinical features; however, severe clinical features including mortality were encountered among individuals who were not vaccinated.

Keywords: SARS-CoV-2; SARS-CoV-2 omicron variant; outbreaks; vaccination.
 
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