tetano
Editor, Senior Moderator
World J Virol
. 2021 Nov 25;10(6):301-311.
doi: 10.5501/wjv.v10.i6.301.
Impact of COVID-19 on liver disease: From the experimental to the clinic perspective
Sheila Gato[SUP] 1 [/SUP], Ana Lucena-Valera[SUP] 2 [/SUP], Rocío Muñoz-Hernández[SUP] 1 [/SUP], José Manuel Sousa[SUP] 2 [/SUP], Manuel Romero-Gómez[SUP] 1 [/SUP], Javier Ampuero[SUP] 1 [/SUP]
Affiliations
Abstract
Coronavirus disease 2019 (COVID-19) has caused a global pandemic unprecedented in over a century. Although severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a predominantly respiratory infection, various degrees of liver function abnormalities have been reported. Pre-existing liver disease in patients with SARS-CoV-2 infection has not been comprehensively evaluated in most studies, but it can critically compromise survival and trigger hepatic decompensation. The collapse of the healthcare services has negatively impacted the diagnosis, monitoring, and treatment of liver diseases in non-COVID-19 patients. In this review, we aim to discuss the impact of COVID-19 on liver disease from the experimental to the clinic perspective.
Keywords: COVID 19; Liver disease; SARS-CoV-2; Transaminases.
. 2021 Nov 25;10(6):301-311.
doi: 10.5501/wjv.v10.i6.301.
Impact of COVID-19 on liver disease: From the experimental to the clinic perspective
Sheila Gato[SUP] 1 [/SUP], Ana Lucena-Valera[SUP] 2 [/SUP], Rocío Muñoz-Hernández[SUP] 1 [/SUP], José Manuel Sousa[SUP] 2 [/SUP], Manuel Romero-Gómez[SUP] 1 [/SUP], Javier Ampuero[SUP] 1 [/SUP]
Affiliations
- PMID: 34909404
- PMCID: PMC8641041
- DOI: 10.5501/wjv.v10.i6.301
Abstract
Coronavirus disease 2019 (COVID-19) has caused a global pandemic unprecedented in over a century. Although severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a predominantly respiratory infection, various degrees of liver function abnormalities have been reported. Pre-existing liver disease in patients with SARS-CoV-2 infection has not been comprehensively evaluated in most studies, but it can critically compromise survival and trigger hepatic decompensation. The collapse of the healthcare services has negatively impacted the diagnosis, monitoring, and treatment of liver diseases in non-COVID-19 patients. In this review, we aim to discuss the impact of COVID-19 on liver disease from the experimental to the clinic perspective.
Keywords: COVID 19; Liver disease; SARS-CoV-2; Transaminases.