tetano
Editor, Senior Moderator
World J Clin Cases
. 2022 May 6;10(13):3969-3980.
doi: 10.12998/wjcc.v10.i13.3969.
COVID-19 and liver diseases, what we know so far
Mohamed Elnaggar[SUP] 1 [/SUP], Ahmed Abomhya[SUP] 2 [/SUP], Ismail Elkhattib[SUP] 3 [/SUP], Nabila Dawoud[SUP] 4 [/SUP], Rajkumar Doshi[SUP] 5 [/SUP]
Affiliations
Abstract
Coronavirus disease 2019 (COVID-19) pneumonia outbreak started in December 2019. On March 12, 2020, the World Health Organization (WHO) declared that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) constitutes a pandemic, and as of May 2021, SARS-CoV-2 has infected over 167.3 million patients, including 3.4 million deaths, reported to WHO. In this review, we will focus on the relationship between SARS-CoV-2 infection and the liver. We will discuss how chronic liver diseases affect the COVID-19 disease course and outcomes. We will also discuss the SARS-CoV-2 effects on the liver, mechanisms of acute liver injury, and potential management plans.
Keywords: COIVD-19; Hepatocellular carcinoma; Liver diseases; Non alcoholic fatty liver; SARS-CoV-2; Transaminases.
. 2022 May 6;10(13):3969-3980.
doi: 10.12998/wjcc.v10.i13.3969.
COVID-19 and liver diseases, what we know so far
Mohamed Elnaggar[SUP] 1 [/SUP], Ahmed Abomhya[SUP] 2 [/SUP], Ismail Elkhattib[SUP] 3 [/SUP], Nabila Dawoud[SUP] 4 [/SUP], Rajkumar Doshi[SUP] 5 [/SUP]
Affiliations
- PMID: 35665122
- PMCID: PMC9131221
- DOI: 10.12998/wjcc.v10.i13.3969
Abstract
Coronavirus disease 2019 (COVID-19) pneumonia outbreak started in December 2019. On March 12, 2020, the World Health Organization (WHO) declared that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) constitutes a pandemic, and as of May 2021, SARS-CoV-2 has infected over 167.3 million patients, including 3.4 million deaths, reported to WHO. In this review, we will focus on the relationship between SARS-CoV-2 infection and the liver. We will discuss how chronic liver diseases affect the COVID-19 disease course and outcomes. We will also discuss the SARS-CoV-2 effects on the liver, mechanisms of acute liver injury, and potential management plans.
Keywords: COIVD-19; Hepatocellular carcinoma; Liver diseases; Non alcoholic fatty liver; SARS-CoV-2; Transaminases.