Giuseppe
Emeritus
WHO new update about H1N1 seasonal human influenza viruses resistant to oseltamivir at: http://www.flutrackers.com/forum/showpost.php?p=175296&postcount=137
Excerpts:
In South Africa, a total of 139 A(H1N1) viruses have been isolated during the 2008 influenza season to date.
Of those, 107 isolates have been tested for oseltamivir resistance by the National Institute of Communicable Diseases (NICD) and 100% were found to be resistant to oseltamivir by genotypic analysis.
Only one of these 107 patients was receiving oseltamivir at the time of sampling, and no unusual clinical features or underlying conditions were found.
From Australia, 10 of 10 A(H1N1) viruses tested, and from Chile, 4 of 32 A (H1N1) viruses tested showed the specific neuraminidase mutation (H274Y) associated with oseltamivir resistance.
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Excerpts:
In South Africa, a total of 139 A(H1N1) viruses have been isolated during the 2008 influenza season to date.
Of those, 107 isolates have been tested for oseltamivir resistance by the National Institute of Communicable Diseases (NICD) and 100% were found to be resistant to oseltamivir by genotypic analysis.
Only one of these 107 patients was receiving oseltamivir at the time of sampling, and no unusual clinical features or underlying conditions were found.
From Australia, 10 of 10 A(H1N1) viruses tested, and from Chile, 4 of 32 A (H1N1) viruses tested showed the specific neuraminidase mutation (H274Y) associated with oseltamivir resistance.
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