tetano
Editor, Senior Moderator
Appl Environ Microbiol. 2014 May 9. [Epub ahead of print]
Wipes Coated with a Singlet Oxygen Producing Photosensitizer are Effective Against Human Influenza Virus but not Against Norovirus.
Verhaelen K1, Bouwknegt M, Rutjes S, de Roda Husman AM, Duizer E.
Author information
Abstract
Transmission of enteric and respiratory viruses, including human norovirus (hNoV) and human influenza virus, may involve surfaces. In food-preparation and health-care settings, surfaces are cleaned with wipes, however, wiping may not efficiently reduce contamination or even spread viruses, increasing a potential public health risk. The virucidal properties of wipes with a singlet oxygen generating immobilized photosensitizer (IPS) coating were compared to similar but uncoated wipes (non-IPS) and to commonly used viscose wipes. Wipes were spiked with hNoV GI.4 and GII.4, murine norovirus (MNV-1), human adenovirus (hAdV-5) and influenza virus H1N1 to study viral persistence. We also determined residual and transferred virus proportions on steel carries after successively wiping a contaminated and uncontaminated steel carrier. Only on IPS-wipes, influenza viruses were promptly inactivated with a 5log10 reduction. D-values of infectious MNV-1 and hAdV-5 were 8.7 and 7.0 h on IPS-wipes, 11.6 and 9.3 h on non-IPS wipes and 10.2 and 8.2 h on viscose wipes. Independent of the type of wipe, dry cleaning removed, or drastically reduced, initial spot contamination of hNoV on surfaces. All wipes transferred hNoV to an uncontaminated carrier, however, the risk of continued transmission by reuse of wipes after 6 and 24 h was limited for all viruses. We conclude that cleaning wet spots with dry wipes efficiently reduced spot contamination on surfaces, but that cross-contamination of noroviruses by wiping may result in an increased public health risk at high initial virus loads. For influenza, IPS-wipes present an efficient one-step procedure for cleaning and disinfecting contaminated surfaces.
PMID:
24814795
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/24814795
Wipes Coated with a Singlet Oxygen Producing Photosensitizer are Effective Against Human Influenza Virus but not Against Norovirus.
Verhaelen K1, Bouwknegt M, Rutjes S, de Roda Husman AM, Duizer E.
Author information
Abstract
Transmission of enteric and respiratory viruses, including human norovirus (hNoV) and human influenza virus, may involve surfaces. In food-preparation and health-care settings, surfaces are cleaned with wipes, however, wiping may not efficiently reduce contamination or even spread viruses, increasing a potential public health risk. The virucidal properties of wipes with a singlet oxygen generating immobilized photosensitizer (IPS) coating were compared to similar but uncoated wipes (non-IPS) and to commonly used viscose wipes. Wipes were spiked with hNoV GI.4 and GII.4, murine norovirus (MNV-1), human adenovirus (hAdV-5) and influenza virus H1N1 to study viral persistence. We also determined residual and transferred virus proportions on steel carries after successively wiping a contaminated and uncontaminated steel carrier. Only on IPS-wipes, influenza viruses were promptly inactivated with a 5log10 reduction. D-values of infectious MNV-1 and hAdV-5 were 8.7 and 7.0 h on IPS-wipes, 11.6 and 9.3 h on non-IPS wipes and 10.2 and 8.2 h on viscose wipes. Independent of the type of wipe, dry cleaning removed, or drastically reduced, initial spot contamination of hNoV on surfaces. All wipes transferred hNoV to an uncontaminated carrier, however, the risk of continued transmission by reuse of wipes after 6 and 24 h was limited for all viruses. We conclude that cleaning wet spots with dry wipes efficiently reduced spot contamination on surfaces, but that cross-contamination of noroviruses by wiping may result in an increased public health risk at high initial virus loads. For influenza, IPS-wipes present an efficient one-step procedure for cleaning and disinfecting contaminated surfaces.
PMID:
24814795
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/24814795