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Wien Klin Wochenschr . Acute amnestic syndrome with hippocampal lesion due to influenza B-associated encephalopathy

tetano

Editor, Senior Moderator
Wien Klin Wochenschr


. 2020 Aug 10.
doi: 10.1007/s00508-020-01721-x. Online ahead of print.
Acute amnestic syndrome with hippocampal lesion due to influenza B-associated encephalopathy


Kitty Koll[SUP] 1 [/SUP], Susanne Willinger[SUP] 2 [/SUP], Karoline Urlesberger[SUP] 1 [/SUP], Walter Pirker[SUP] 3 [/SUP]



Affiliations

Abstract

Acute encephalopathy is a rare complication of influenza, particularly in adults. We report the case of a 77-year-old woman presenting with complete anterograde and significant retrograde amnesia developing during an influenza B infection. Cranial magnetic resonance imaging (MRI) showed hippocampal lesions including restricted diffusion during the acute phase. Symptoms partially improved following treatment with intravenous methylprednisolone and immunoglobulins but an amnesic syndrome persisted. We discuss possible causes of neurological complications in influenza infections.

Keywords: Antineuronal antibodies; Cytokine storm; Influenza virus; Neurotropism; Viral encephalitis.
 
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