Re: WHO - Swine Flu Virtual Press Briefings - Archive
12 May 2009 press briefing
Listen to Dr Nikki Shindo, Medical Officer, WHO Global Influenza Programme [mp3 41Mb]
No transcript yet
5251 cases in 30 countries
<meta http-equiv="Content-Type" content="text/html; charset=utf-8"><meta name="ProgId" content="Word.Document"><meta name="Generator" content="Microsoft Word 10"><meta name="Originator" content="Microsoft Word 10"><link rel="File-List" href="file:///D:%5CDOCUME%7E1%5CADMINI%7E1%5CLOCALS%7E1%5CTemp%5Cmsohtml1%5C01%5Cclip_filelist.xml"><o:smarttagtype namespaceuri="urn:schemas-microsoft-com
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They are working on an ?Initial Guidance for Clinical Management? document for release soon
Key points
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Regarding numbers: they are likely to be skewed as they are based on lab confirmed cases while <st1:country-region><st1
lace>Mexico</st1
lace></st1:country-region> and the <st1:country-region><st1
lace>USA</st1
lace></st1:country-region> have been prioritising the testing of samples from severe cases. All of the following should be read with this in mind.
<!--[if !supportLists]-->-[FONT="] [/FONT]<!--[endif]-->About 10% are requiring hospitalisation & the preliminary <st1:stockticker>CFR</st1:stockticker> is 1.4% (remember based on skewed confirmed data) also remember this is with current high levels of health care access at this pre-pandemic stage.
<!--[if !supportLists]-->-[FONT="] [/FONT]<!--[endif]-->The above, plus the fear of antiviral resistance acquisition, mean vaccine production should be pursued.
<!--[if !supportLists]-->-[FONT="] [/FONT]<!--[endif]-->Clinical cases do not follow the seasonal flu pattern. Seasonal flu death rates include all deaths in which flu is a factor.
<!--[if !supportLists]-->-[FONT="] [/FONT]<!--[endif]-->Most cases are mild but, of the severe cases/deaths, they fall into two groups those that have other medical conditions and a group of young healthy adults. The high risk factors include pregnancy, the immunocompromised & and those that would be regarded as high risk for seasonal flu. They are looking hard at the young healthy group for a common factor but numbers are small and no pattern yet.
<!--[if !supportLists]-->-[FONT="] [/FONT]<!--[endif]-->Current guidance for treatment of general population: Do not use antivirals and do not hospitalise. Do use antipyretics, analgesics, analgesics (but not aspirin), antibiotics & oxygen as required - also build up stockpiles of these.
<!--[if !supportLists]-->-[FONT="] [/FONT]<!--[endif]-->Pneumonia: Primary in severe cases, little secondary (but expect this to change), some ventilator associated case.
<!--[if !supportLists]-->-[FONT="] [/FONT]<!--[endif]-->They are urgently seeking data from physicians regarding treatment results with antivirals, especially zanamivir. While resistance is confirmed in vitro little is known about clinical efficacy.
<!--[if !supportLists]-->-[FONT="] [/FONT]<!--[endif]-->Due to the complex developing system of strains and resistance they are building a matrix ? along with rapid regional strain prevalence detection ? more clinicians to use in choosing treatment options.
