WHO: A(H7N9) candidate vaccine viruses, 30 July 2013

[Biological]

Summary of status of development and availability of avian influenza A(H7N9) candidate vaccine viruses
30 July 2013

Parent virus Candidate vaccine virus Type of virus or reassortant Developing institute Available from

A/Shanghai/2/2013
Synthetic HA&NA
IDCDC-RG32A* Reverse genetics CDC, USA CDC, USA
NIBRG-267** Reverse genetics NIBSC, UK NIBSC, UK
CBER-RG4A** Reverse genetics CBER, USA CBER, USA

A/Anhui/1/2013
Wild type virus WHO CCs
NIBRG-268* Reverse genetics NIBSC, UK NIBSC, UK
NIIDRG-10.1* Reverse genetics NIID, Japan NIID, Japan

* These viruses are candidate vaccine viruses which have passed relevant safety testing and two-way haemagglutination inhibition (HI) tests. They can be handled under BSL-2 enhanced containment1.
** These are potential candidate vaccine viruses which have passed relevant safety testing and can be handled under BSL-2 enhanced containment1. Full virus characterization is yet to be finished.
1 http://www.who.int/biologicals/areas/vaccines/influenza/biosafety_risk_assessment_10may2013.pdf
Institutes contact details for candidate vaccine viruses orders/information:
CBER: Zhiping.Ye@fda.hhs.gov
CDC: rvd6@cdc.gov
NIBSC: standards@nibsc.hpa.org.uk or enquiries@nibsc.hpa.org.uk
NIID: nobusawa@nih.go.jp
WHO CCs: http://www.who.int/influenza/gisrs_laboratory/collaborating_centres/list/en/
For general enquiries, please contact gisrs-whohq@who.int
For other candidate vaccine viruses and potency testing reagents, please go to
http://www.who.int/influenza/vaccines/virus/candidates_reagents/home/

http://www.who.int/influenza/vaccines/virus/candidates_reagents/summary_a_h7n9_cvv_20130730.pdf

Earlier report
WHO Summary of status of development and availability of avian influenza A(H7N9) candidate vaccine viruses, 12 July 2013
http://www.who.int/influenza/vaccines/virus/candidates_reagents/summary_a_h7n9_cvv_20130712.pdf