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Vogt-Koyanagi-Harada Disease Associated with Influenza A Virus Infection: A Case Report

tetano

Editor, Senior Moderator
Intern Med. 2018 Jan 11. doi: 10.2169/internalmedicine.9819-17. [Epub ahead of print]
[h=1]Vogt-Koyanagi-Harada Disease Associated with Influenza A Virus Infection: A Case Report.[/h] Yoshino N[SUP]1[/SUP], Kawamura A[SUP]1[/SUP], Ishii A[SUP]1[/SUP], Yoshida K[SUP]1[/SUP], Watanabe T[SUP]1[/SUP], Yamashita T[SUP]1[/SUP], Fukuchi T[SUP]1[/SUP], Toyoda F[SUP]2[/SUP], Kakehashi A[SUP]2[/SUP], Sugawara H[SUP]1[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] We herein report a case of a 31-year-old Japanese man who simultaneously had a positive influenza A virus antigen test result and Vogt-Koyanagi-Harada disease (VKHD), demonstrated by both diffuse multiple early hyperfluorescent points on fluorescein fundus photography and serous retinal detachments on optical coherence tomography. He had meningitis. It was difficult to determine whether the main cause of meningitis was influenza A or VKHD. After initial treatment with peramivir for influenza A and then methylprednisolone pulse with subsequent corticosteroid therapy for VKHD, his symptoms improved gradually. These findings suggest that influenza A virus infection contributes to the onset or exacerbation of VKHD.


[h=4]KEYWORDS:[/h] Vogt-Koyanagi-Harada disease; corticosteroids therapy; influenza A virus; meningitis; peramivir

PMID: 29321438 DOI: 10.2169/internalmedicine.9819-17
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