Shiloh
Editor, Senior Moderator
Source: https://pubmed.ncbi.nlm.nih.gov/33164936/
Vitamin D Supplementation Improves Cognitive Function Through Reducing Oxidative Stress Regulated by Telomere Length in Older Adults with Mild Cognitive Impairment: A 12-Month Randomized Controlled Trial
Tong Yang 1 2 , Hualou Wang 1 2 , Ying Xiong 3 , Chong Chen 4 5 6 7 , Keran Duan 8 , Jingya Jia 1 2 , Fei Ma 1 2
Affiliations
PMID: 33164936 DOI: 10.3233/JAD-200926
Abstract
Background: Cognitive decline in older adults is a serious public health problem today. Association between vitamin D supplementation and cognition remains controversial.
Objective: To determine whether a 12-month vitamin D supplementation improves cognitive function in elderly subjects with mild cognitive impairment (MCI), and whether it is mediated through the mechanism in which telomere length (TL) regulate oxidative stress...
...Conclusion: Vitamin D supplementation for 12 months appears to improve cognitive function through reducing oxidative stress regulated by increased TL in order adults with MCI. Vitamin D may be a promising public health strategy to prevent cognitive decline.
Vitamin D Supplementation Improves Cognitive Function Through Reducing Oxidative Stress Regulated by Telomere Length in Older Adults with Mild Cognitive Impairment: A 12-Month Randomized Controlled Trial
Tong Yang 1 2 , Hualou Wang 1 2 , Ying Xiong 3 , Chong Chen 4 5 6 7 , Keran Duan 8 , Jingya Jia 1 2 , Fei Ma 1 2
Affiliations
PMID: 33164936 DOI: 10.3233/JAD-200926
Abstract
Background: Cognitive decline in older adults is a serious public health problem today. Association between vitamin D supplementation and cognition remains controversial.
Objective: To determine whether a 12-month vitamin D supplementation improves cognitive function in elderly subjects with mild cognitive impairment (MCI), and whether it is mediated through the mechanism in which telomere length (TL) regulate oxidative stress...
...Conclusion: Vitamin D supplementation for 12 months appears to improve cognitive function through reducing oxidative stress regulated by increased TL in order adults with MCI. Vitamin D may be a promising public health strategy to prevent cognitive decline.