tetano
Editor, Senior Moderator
Viruses
. 2022 Oct 14;14(10):2255.
doi: 10.3390/v14102255.
Rhabdomyolysis after COVID-19 Infection: A Case Report and Review of the Literature
Monica Bawor[SUP] 1 [/SUP], Shwetha Sairam[SUP] 1 [/SUP], Rachel Rozewicz[SUP] 1 [/SUP], Stuart Viegas[SUP] 2 [/SUP], Alexander N Comninos[SUP] 3 4 [/SUP], Ali Abbara[SUP] 3 4 [/SUP]
Affiliations
Abstract
Rhabdomyolysis is a condition in which muscle breaks down potentially leading to renal dysfunction, and often occurs secondary to a precipitating factor. Viral or bacterial infections are common precipitants for initiating rhabdomyolysis. Recently, healthcare systems across the world have been challenged by a pandemic of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) causing 'coronavirus disease 2019' (COVID-19) disease. SARS-CoV-2 infection is recognized to cause respiratory and cardiovascular compromise, thromboembolic events, and acute kidney injury (AKI); however, it is not known whether it can precipitate rhabdomyolysis, with only a limited number of cases of SARS-CoV-2 infection preceding rhabdomyolysis reported to date. Here, we report the case of a 64-year-old woman who developed rhabdomyolysis shortly after SARS-CoV-2 infection and COVID-19. She initially presented with muscular pain, a creatine kinase level of 119,301 IU/L, and a mild rise in her creatinine level to 92 µmol/L, but successfully recovered with intravenous fluid support. We also review the literature to summarise previously reported cases of rhabdomyolysis precipitated by SARS-CoV-2, highlighting the need to consider this diagnosis in patients presenting with SARS-CoV-2 and myalgia.
Keywords: COVID-19 disease; SARS-CoV-2 infection; rhabdomyolysis; viral-induced rhabdomyolysis.
. 2022 Oct 14;14(10):2255.
doi: 10.3390/v14102255.
Rhabdomyolysis after COVID-19 Infection: A Case Report and Review of the Literature
Monica Bawor[SUP] 1 [/SUP], Shwetha Sairam[SUP] 1 [/SUP], Rachel Rozewicz[SUP] 1 [/SUP], Stuart Viegas[SUP] 2 [/SUP], Alexander N Comninos[SUP] 3 4 [/SUP], Ali Abbara[SUP] 3 4 [/SUP]
Affiliations
- PMID: 36298810
- DOI: 10.3390/v14102255
Abstract
Rhabdomyolysis is a condition in which muscle breaks down potentially leading to renal dysfunction, and often occurs secondary to a precipitating factor. Viral or bacterial infections are common precipitants for initiating rhabdomyolysis. Recently, healthcare systems across the world have been challenged by a pandemic of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) causing 'coronavirus disease 2019' (COVID-19) disease. SARS-CoV-2 infection is recognized to cause respiratory and cardiovascular compromise, thromboembolic events, and acute kidney injury (AKI); however, it is not known whether it can precipitate rhabdomyolysis, with only a limited number of cases of SARS-CoV-2 infection preceding rhabdomyolysis reported to date. Here, we report the case of a 64-year-old woman who developed rhabdomyolysis shortly after SARS-CoV-2 infection and COVID-19. She initially presented with muscular pain, a creatine kinase level of 119,301 IU/L, and a mild rise in her creatinine level to 92 µmol/L, but successfully recovered with intravenous fluid support. We also review the literature to summarise previously reported cases of rhabdomyolysis precipitated by SARS-CoV-2, highlighting the need to consider this diagnosis in patients presenting with SARS-CoV-2 and myalgia.
Keywords: COVID-19 disease; SARS-CoV-2 infection; rhabdomyolysis; viral-induced rhabdomyolysis.