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Viruses associated with acute respiratory infections and influenza-like illness among outpatients from the Influenza Incidence Surveillance Project, 2

tetano

Editor, Senior Moderator
J Infect Dis. 2013 Dec 12. [Epub ahead of print]
Viruses associated with acute respiratory infections and influenza-like illness among outpatients from the Influenza Incidence Surveillance Project, 2010-2011.
Fowlkes A, Giorgi A, Erdman D, Temte J, Goodin K, Di Lonardo S, Sun Y, Martin K, Feist M, Linz R, Boulton R, Bancroft E, McHugh L, Lojo J, Filbert K, Finelli L; for the IISP Working Group.
Author information
Abstract

Background. The Influenza Incidence Surveillance Project (IISP) monitored outpatient acute respiratory infection (ARI) and influenza like illness (ILI) to determine the incidence and contribution of associated viral etiologies.Methods. From August 2010 through July 2011, 57 outpatient healthcare providers with enumerated patient populations in 12 US sites reported weekly the number of ILI and ARI (> 2 respiratory symptoms not meeting ILI criteria) visits and collected respiratory specimens on a subset for viral testing. Incidence was estimated using number of patients in the practice as the denominator, and virus-specific incidence was extrapolated from the proportion of patients testing positive.Results. The age-adjusted annual incidence of outpatient visits for ARI and ILI combined was 95/1,000 population, with a viral etiology identified in 58% of specimens. Most frequently detected were rhinoviruses/enteroviruses (RV/EV) and influenza (21% each), resulting in an extrapolated incidence of 20 and 19/1,000 population, respectively. The influenza incidence was highest among patients aged 2 to 17 years, while other viruses had varied patterns among age groups.Conclusions. The IISP provides a unique opportunity to estimate outpatient respiratory illness burden by etiology. Influenza and RV/EV infections represent a substantial burden of respiratory disease in the US outpatient setting, particularly among children.

PMID:
24338352
[PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/24338352
 
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