tetano
Editor, Senior Moderator
J Med Virol. 2016 Dec 12. doi: 10.1002/jmv.24751. [Epub ahead of print]
[h=1]Viral pathogens among elderly people with acute respiratory infections in Shanghai, China: Preliminary results from a laboratory-based surveillance, 2012-2015.[/h] Ye C[SUP]1,[/SUP][SUP]2[/SUP], Zhu W[SUP]2[/SUP], Yu J[SUP]3[/SUP], Li Z[SUP]4[/SUP], Fu Y[SUP]2[/SUP], Lan Y[SUP]5[/SUP], Lai S[SUP]4,[/SUP][SUP]6[/SUP], Wang Y[SUP]2[/SUP], Pan L[SUP]2[/SUP], Sun Q[SUP]2[/SUP], Zhao G[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Acute respiratory infections (ARIs), with viral pathogens as the major contributors, are the most common illnesses worldwide, and increase the morbidity and mortality among the elderly population. The clinical and pathological features of elderly people with ARIs need to be identified for disease intervention. From January 1[SUP]st[/SUP] , 2012 through December 31[SUP]st[/SUP] , 2015, respiratory specimens from patients above 60 years old with ARIs were collected from the outpatient and inpatient settings of six sentinel hospitals in Pudong New Area. Each specimen was tested via multiplex polymerase chain reaction (PCR) for eight target viral etiologies including influenza, human rhinovirus (HRV), human para-influenza virus (PIV), adenovirus (ADV), respiratory syncytial virus (RSV), human metapneumovirus (hMPV), human coronavirus (hCoVs) and human bocavirus (hBoV). A total of 967 elderly patients with ARIs were enrolled, including 589 (60.91%) males, and the median age was 73 years old. 306 (31.64%) patients were tested positive for any one of the eight viruses, including 276 single infections and 30 co-infections. Influenza was the predominant virus (14.17%, 137/967), detected from 21.35% (76/356) of the outpatients and 9.98% (61/611) of the inpatients. Influenza infections presented two annual seasonal peaks during winter and summer. Compared with non-influenza patients, those with influenza were more likely to have fever, cough, sore throat and fatigue. This study identified influenza as the leading viral pathogen among elderly with ARIs, and two seasonal epidemic peaks were observed in Shanghai. An influenza vaccination strategy needs to be advocated for the elderly population. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.
[h=4]KEYWORDS:[/h] Influenza virus; Public policy; Respiratory track
PMID: 27943329 DOI: 10.1002/jmv.24751
[PubMed - as supplied by publisher]
[h=1]Viral pathogens among elderly people with acute respiratory infections in Shanghai, China: Preliminary results from a laboratory-based surveillance, 2012-2015.[/h] Ye C[SUP]1,[/SUP][SUP]2[/SUP], Zhu W[SUP]2[/SUP], Yu J[SUP]3[/SUP], Li Z[SUP]4[/SUP], Fu Y[SUP]2[/SUP], Lan Y[SUP]5[/SUP], Lai S[SUP]4,[/SUP][SUP]6[/SUP], Wang Y[SUP]2[/SUP], Pan L[SUP]2[/SUP], Sun Q[SUP]2[/SUP], Zhao G[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Acute respiratory infections (ARIs), with viral pathogens as the major contributors, are the most common illnesses worldwide, and increase the morbidity and mortality among the elderly population. The clinical and pathological features of elderly people with ARIs need to be identified for disease intervention. From January 1[SUP]st[/SUP] , 2012 through December 31[SUP]st[/SUP] , 2015, respiratory specimens from patients above 60 years old with ARIs were collected from the outpatient and inpatient settings of six sentinel hospitals in Pudong New Area. Each specimen was tested via multiplex polymerase chain reaction (PCR) for eight target viral etiologies including influenza, human rhinovirus (HRV), human para-influenza virus (PIV), adenovirus (ADV), respiratory syncytial virus (RSV), human metapneumovirus (hMPV), human coronavirus (hCoVs) and human bocavirus (hBoV). A total of 967 elderly patients with ARIs were enrolled, including 589 (60.91%) males, and the median age was 73 years old. 306 (31.64%) patients were tested positive for any one of the eight viruses, including 276 single infections and 30 co-infections. Influenza was the predominant virus (14.17%, 137/967), detected from 21.35% (76/356) of the outpatients and 9.98% (61/611) of the inpatients. Influenza infections presented two annual seasonal peaks during winter and summer. Compared with non-influenza patients, those with influenza were more likely to have fever, cough, sore throat and fatigue. This study identified influenza as the leading viral pathogen among elderly with ARIs, and two seasonal epidemic peaks were observed in Shanghai. An influenza vaccination strategy needs to be advocated for the elderly population. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.
[h=4]KEYWORDS:[/h] Influenza virus; Public policy; Respiratory track
PMID: 27943329 DOI: 10.1002/jmv.24751
[PubMed - as supplied by publisher]