tetano
Editor, Senior Moderator
Wien Klin Wochenschr. 2016 Nov 7. [Epub ahead of print]
[h=1]Venovenous extracorporeal membrane oxygenation for ARDS: outcome analysis of a Croatian referral center for respiratory ECMO.[/h] Kutle?a M[SUP]1[/SUP], Novokmet A[SUP]2[/SUP], Josipović Mraović R[SUP]2[/SUP], Bar?ić B[SUP]3[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] The use of venovenous extracorporeal membrane oxygenation (VV-ECMO) as a rescue therapy in severe acute respiratory distress syndrome (ARDS) has become well established; however, the affirmation of evidence on VV-ECMO application and the analysis of patient outcomes after VV-ECMO treatment for ARDS continues. The aim of the study is to identify variables that affected the outcome of patients treated with VV-ECMO for severe ARDS outside a major ECMO center.
[h=4]METHODS:[/h] The study included adult patients with severe ARDS treated with ECMO at a tertiary care hospital in Zagreb, Croatia between October 2009 and July 2014. Patients were recruited from a prospective database.
[h=4]RESULTS:[/h] The study enrolled 40 patients, 20 of whom had H1N1-induced ARDS. The hospital mortality was 38%. The difference in mortality and long-term outcome in H1N1-induced ARDS as compared to non-H1N1-induced ARDS was not significant. Variables associated with mortality included immunosuppression, shock at time of admission, acute renal failure, occurrence of heparin-induced thrombocytopenia antibodies, nosocomial sepsis and duration of ECMO.
[h=4]CONCLUSIONS:[/h] The results of our study indicate that ECMO use in severe ARDS is feasible with low mortality and identify or assert the variables associated with adverse outcomes.
[h=4]KEYWORDS:[/h] ARDS; Extracorporeal membrane oxygenation; Heparin-induced thrombocytopenia; Influenza
PMID: 27822747 DOI: 10.1007/s00508-016-1109-3
[PubMed - as supplied by publisher]
[h=1]Venovenous extracorporeal membrane oxygenation for ARDS: outcome analysis of a Croatian referral center for respiratory ECMO.[/h] Kutle?a M[SUP]1[/SUP], Novokmet A[SUP]2[/SUP], Josipović Mraović R[SUP]2[/SUP], Bar?ić B[SUP]3[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] The use of venovenous extracorporeal membrane oxygenation (VV-ECMO) as a rescue therapy in severe acute respiratory distress syndrome (ARDS) has become well established; however, the affirmation of evidence on VV-ECMO application and the analysis of patient outcomes after VV-ECMO treatment for ARDS continues. The aim of the study is to identify variables that affected the outcome of patients treated with VV-ECMO for severe ARDS outside a major ECMO center.
[h=4]METHODS:[/h] The study included adult patients with severe ARDS treated with ECMO at a tertiary care hospital in Zagreb, Croatia between October 2009 and July 2014. Patients were recruited from a prospective database.
[h=4]RESULTS:[/h] The study enrolled 40 patients, 20 of whom had H1N1-induced ARDS. The hospital mortality was 38%. The difference in mortality and long-term outcome in H1N1-induced ARDS as compared to non-H1N1-induced ARDS was not significant. Variables associated with mortality included immunosuppression, shock at time of admission, acute renal failure, occurrence of heparin-induced thrombocytopenia antibodies, nosocomial sepsis and duration of ECMO.
[h=4]CONCLUSIONS:[/h] The results of our study indicate that ECMO use in severe ARDS is feasible with low mortality and identify or assert the variables associated with adverse outcomes.
[h=4]KEYWORDS:[/h] ARDS; Extracorporeal membrane oxygenation; Heparin-induced thrombocytopenia; Influenza
PMID: 27822747 DOI: 10.1007/s00508-016-1109-3
[PubMed - as supplied by publisher]