Mary Wilson
Well-known member
June 05, 2023 08:00 AM Eastern Daylight Time
CAMBRIDGE, Mass. & BRISBANE, Australia -- (BUSINESS WIRE) -- Vaxxas, a clinical-stage biotechnology company commercializing a novel vaccination platform, today announced positive interim results from a Phase I human clinical trial with the first needle-free COVID-19 vaccine candidate delivered using Vaxxas’ proprietary high-density microarray patch (HD-MAP) technology.
The COVID-19 vaccine involves HD-MAP delivery of HexaPro, a second-generation version of the spike protein used in all major U.S. approved COVID-19 vaccines, which was modified to be more stable and immunogenic than its predecessor, giving potential coverage of all known SARS-CoV-2 variants. The HD-MAP COVID-19 vaccine patches were well tolerated, with no serious or severe adverse events. Analysis of samples from day 28 show the HD-MAP COVID-19 vaccine increased relevant antibody levels by 8-fold on average, and the antibody responses indicated a dose dependent trend.
... The Phase I clinical trial is designed to assess the safety, tolerability and immunogenicity of the HD-MAP COVID-19 vaccine candidate in 44 healthy adults, aged 18 – 50 years inclusive, who have had three doses of an authorized COVID-19 vaccine prior to enrollment in this study, with the last dose at least four months prior to participating in the study. ...
https://www.businesswire.com/news/h...c&utm_medium=twitter&utm_source=socialnetwork
CAMBRIDGE, Mass. & BRISBANE, Australia -- (BUSINESS WIRE) -- Vaxxas, a clinical-stage biotechnology company commercializing a novel vaccination platform, today announced positive interim results from a Phase I human clinical trial with the first needle-free COVID-19 vaccine candidate delivered using Vaxxas’ proprietary high-density microarray patch (HD-MAP) technology.
The COVID-19 vaccine involves HD-MAP delivery of HexaPro, a second-generation version of the spike protein used in all major U.S. approved COVID-19 vaccines, which was modified to be more stable and immunogenic than its predecessor, giving potential coverage of all known SARS-CoV-2 variants. The HD-MAP COVID-19 vaccine patches were well tolerated, with no serious or severe adverse events. Analysis of samples from day 28 show the HD-MAP COVID-19 vaccine increased relevant antibody levels by 8-fold on average, and the antibody responses indicated a dose dependent trend.
... The Phase I clinical trial is designed to assess the safety, tolerability and immunogenicity of the HD-MAP COVID-19 vaccine candidate in 44 healthy adults, aged 18 – 50 years inclusive, who have had three doses of an authorized COVID-19 vaccine prior to enrollment in this study, with the last dose at least four months prior to participating in the study. ...
https://www.businesswire.com/news/h...c&utm_medium=twitter&utm_source=socialnetwork