Vaccines (Basel) . Immune Thrombocytopenia Induced by the Chimpanzee Adenovirus-Vectored Vaccine against SARS-CoV-2 Infection

[tetano]

Vaccines (Basel)


. 2021 Dec 16;9(12):1486.
doi: 10.3390/vaccines9121486.
Immune Thrombocytopenia Induced by the Chimpanzee Adenovirus-Vectored Vaccine against SARS-CoV-2 Infection


Po-Wei Liao[SUP] 1 [/SUP], Chieh-Lin Jerry Teng[SUP] 1 2 3 [/SUP], Cheng-Wei Chou[SUP] 1 4 [/SUP]



Affiliations

• PMID: 34960232
• DOI: 10.3390/vaccines9121486

Abstract

We present a case of immune thrombocytopenia (ITP) induced by the chimpanzee adenovirus-vectored vaccine, without evidence of thrombosis, eight days after vaccine administration. The thrombocytopenia condition improved after administering steroid treatment. This adenovirus vaccine had been reported to induce rare side effects, such as immune thrombotic thrombocytopenia. This case report showed that it could also induce immune thrombocytopenia without the presence of thrombosis. Therefore, we should be cautious of this rare side effect as global vaccine administrations against coronavirus disease increase.

Keywords: COVID-19; SARS-CoV-2; adenovirus vaccine; immune thrombocytopenia; ischemic stroke.