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Vaccines (Basel) . COVID-19 Vaccination Status among Pregnant and Postpartum Women-A Cross-Sectional Study on More Than 1000 Individuals

tetano

Editor, Senior Moderator
Vaccines (Basel)


. 2022 Jul 25;10(8):1179.
doi: 10.3390/vaccines10081179.
COVID-19 Vaccination Status among Pregnant and Postpartum Women-A Cross-Sectional Study on More Than 1000 Individuals


Urszula Nowacka[SUP] 1 [/SUP], Paulina Malarkiewicz[SUP] 2 [/SUP], Janusz Sierdzinski[SUP] 3 [/SUP], Aleksandra Januszaniec[SUP] 1 [/SUP], Szymon Kozłowski[SUP] 1 [/SUP], Tadeusz Issat[SUP] 1 [/SUP]



Affiliations

Abstract

Pregnancy is a well-known factor for vaccine hesitancy and immunization remains the most effective form of prevention against coronavirus disease (COVID-19) related complications. The objective was to estimate vaccine uptake and hesitancy rate, characteristics, and factors contributing to a decision-making process among pregnant and postpartum individuals. This was a prospective cross-sectional study on 1033 pregnant (54.1%) and postpartum (45.9%) women conducted between December 2021 and March 2022 in a tertiary center for maternal-fetal medicine. Logistic regression was used to assess characteristics related to the vaccination decision process. Among responders, 74% were vaccinated and 26% were hesitant (9% planning to vaccinate and 17% totally opposed). Only 59.8% were offered a vaccine by healthcare professionals. Women with higher levels of education (OR 2.26, p < 0.0001), who received positive feedback about vaccination (OR 2.74, p = 0.0172), or were informed about COVID-19 complications in pregnancy (OR 2.6, p < 0.0001) were most likely to accept the vaccination. Hesitancy was associated with multiparity (≥3, OR 4.76, p = 0.006), worse educational status (OR 2.29, p < 0.0001), and lack of previous COVID-19 infection (OR 1.89, p < 0.0001). The most common reason for rejection was insufficient safety data (57%). Understanding factors behind vaccination status is crucial in lowering complications in mothers and newborns and targeted action may facilitate the uptake.

Keywords: COVID-19; Tdap vaccine; fetus; maternal–fetal medicine; pregnancy; vaccination; vaccination status; vaccine; vaccine hesitancy; vaccine uptake.
 
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