tetano
Editor, Senior Moderator
Vaccine
. 2021 Dec 4;S0264-410X(21)01579-6.
doi: 10.1016/j.vaccine.2021.11.088. Online ahead of print.
Influenza vaccination uptake among Canadian adults before and during the COVID-19 pandemic: An analysis of the Canadian Longitudinal study on Aging (CLSA)
Giorgia Sulis[SUP] 1 [/SUP], Nicole E Basta[SUP] 2 [/SUP], Christina Wolfson[SUP] 3 [/SUP], Susan A Kirkland[SUP] 4 [/SUP], Jacqueline McMillan[SUP] 5 [/SUP], Lauren E Griffith[SUP] 6 [/SUP], Parminder Raina[SUP] 7 [/SUP], Canadian Longitudinal Study on Aging (CLSA) Team
Affiliations
Abstract
Introduction: Understanding how influenza vaccine uptake changed during the 2020/2021 influenza season compared to previous pre-pandemic seasons is a key priority, as is identifying the relationship between prior influenza vaccination and COVID-19 vaccine willingness.
Methods: We analyzed data from a large, nationally representative cohort of Canadian residents aged 50 and older to assess influenza vaccination status three times between 2015 and 2020. We investigated: 1) changes in self-reported influenza vaccine uptake, 2) predictors of influenza vaccine uptake in 2020/2021, and 3) the association between influenza vaccination history and self-reported COVID-19 vaccine willingness using logistic regression models.
Results: Among 23,385 participants analyzed for aims 1-2, influenza vaccination increased over time: 14,114 (60.4%) in 2015-2018, 15,692 (67.1%) in 2019/2020, and 19,186 (82.0%; combining those already vaccinated and those planning to get a vaccine) in 2020/2021. After controlling for socio-demographics, history of influenza vaccination was most strongly associated with influenza vaccination in 2020/2021 (adjusted odds ratio [aOR] 147.9 [95% CI: 120.9-180.9]); this association remained after accounting for multiple health and pandemic-related factors (aOR 140.3 [95% CI: 114.5-171.8]). To a lesser degree, those more concerned about COVID-19 were also more likely to report influenza vaccination in fall 2020, whereas those reporting a very negative impact of the pandemic were less likely to get vaccinated. Among 23,819 participants with information on COVID-19 vaccine willingness during the last quarter of 2020 (aim 3), prior influenza vaccination was most strongly associated with willingness to get a COVID-19 vaccine (aOR 15.1 [95% CI: 13.5-16.8] for those who had received influenza vaccine at all previous timepoints versus none).
Conclusions: Our analysis highlights the importance of previous vaccination in driving vaccination uptake and willingness. Efforts to increase vaccination coverage for influenza and COVID-19 should target individuals who do not routinely engage with immunization services regardless of demographic factors.
Keywords: Adults; CLSA; COVID-19; Canada; Influenza; SARS-CoV-2; Vaccination; Vaccine.
. 2021 Dec 4;S0264-410X(21)01579-6.
doi: 10.1016/j.vaccine.2021.11.088. Online ahead of print.
Influenza vaccination uptake among Canadian adults before and during the COVID-19 pandemic: An analysis of the Canadian Longitudinal study on Aging (CLSA)
Giorgia Sulis[SUP] 1 [/SUP], Nicole E Basta[SUP] 2 [/SUP], Christina Wolfson[SUP] 3 [/SUP], Susan A Kirkland[SUP] 4 [/SUP], Jacqueline McMillan[SUP] 5 [/SUP], Lauren E Griffith[SUP] 6 [/SUP], Parminder Raina[SUP] 7 [/SUP], Canadian Longitudinal Study on Aging (CLSA) Team
Affiliations
- PMID: 34916102
- DOI: 10.1016/j.vaccine.2021.11.088
Abstract
Introduction: Understanding how influenza vaccine uptake changed during the 2020/2021 influenza season compared to previous pre-pandemic seasons is a key priority, as is identifying the relationship between prior influenza vaccination and COVID-19 vaccine willingness.
Methods: We analyzed data from a large, nationally representative cohort of Canadian residents aged 50 and older to assess influenza vaccination status three times between 2015 and 2020. We investigated: 1) changes in self-reported influenza vaccine uptake, 2) predictors of influenza vaccine uptake in 2020/2021, and 3) the association between influenza vaccination history and self-reported COVID-19 vaccine willingness using logistic regression models.
Results: Among 23,385 participants analyzed for aims 1-2, influenza vaccination increased over time: 14,114 (60.4%) in 2015-2018, 15,692 (67.1%) in 2019/2020, and 19,186 (82.0%; combining those already vaccinated and those planning to get a vaccine) in 2020/2021. After controlling for socio-demographics, history of influenza vaccination was most strongly associated with influenza vaccination in 2020/2021 (adjusted odds ratio [aOR] 147.9 [95% CI: 120.9-180.9]); this association remained after accounting for multiple health and pandemic-related factors (aOR 140.3 [95% CI: 114.5-171.8]). To a lesser degree, those more concerned about COVID-19 were also more likely to report influenza vaccination in fall 2020, whereas those reporting a very negative impact of the pandemic were less likely to get vaccinated. Among 23,819 participants with information on COVID-19 vaccine willingness during the last quarter of 2020 (aim 3), prior influenza vaccination was most strongly associated with willingness to get a COVID-19 vaccine (aOR 15.1 [95% CI: 13.5-16.8] for those who had received influenza vaccine at all previous timepoints versus none).
Conclusions: Our analysis highlights the importance of previous vaccination in driving vaccination uptake and willingness. Efforts to increase vaccination coverage for influenza and COVID-19 should target individuals who do not routinely engage with immunization services regardless of demographic factors.
Keywords: Adults; CLSA; COVID-19; Canada; Influenza; SARS-CoV-2; Vaccination; Vaccine.