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Vaccine. Influenza surveillance in a cohort of HIV-infected children and adolescents immunized against seasonal influenza.

Giuseppe

Emeritus
Influenza surveillance in a cohort of HIV-infected children and adolescents immunized against seasonal influenza. (Vaccine, abstract, edited)

18. Vaccine. 2010 Jan 24. [Epub ahead of print]

Influenza surveillance in a cohort of HIV-infected children and adolescents immunized against seasonal influenza.

Amendola A, Pariani E, Vigan? A, Erba P, Zappa A, Giacomet V, Tanzi E, Zuccotti GV, Zanetti A. - Universit? degli Studi di Milano, Dipartimento di Sanit? Pubblica-Microbiologia-Virologia, Via Pascal 36, 20133 Milan, Italy.


During the 2006-2007 season, 19 HIV-uninfected and 33 HIV-infected children and adolescents with full immunovirologic response to HAART were immunized against influenza and subsequently followed up. One month post-immunization all subjects had protective antibodies titres which persisted for the whole influenza season. Seven vaccinees (four HIV-infected and three HIV-uninfected) were found to be infected by influenza viruses during the epidemic, but disease was lab-confirmed only in two HIV-infected subjects. Both presented a benign clinical course and were infected by an A/Brisbane/10/07-H3N2-like virus. These data indicate that HIV-infected subjects benefit from routine seasonal influenza vaccination.

Copyright ? 2010. Published by Elsevier Ltd.

PMID: 20105427 [PubMed - as supplied by publisher]
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