Giuseppe
Emeritus
Evaluation of Southern Hemisphere influenza vaccine recommendations. (Vaccine, abstract, edited)
11. Vaccine. 2010 Feb 10. [Epub ahead of print]
Evaluation of Southern Hemisphere influenza vaccine recommendations.
Richard SA, Viboud C, Miller MA. - Fogarty International Center, National Institutes of Health, Bethesda, MD, United States.
In 1999, the World Health Organization switched from annual to semi-annual recommendations for influenza vaccine composition. We compared the antigenic match between recommendations and circulating viruses before and after 1999. Vaccine match proportion for A/H3N2 viruses increased from 31% to 59% in the Southern Hemisphere (P<0.05), and is now comparable to that in the Northern Hemisphere. Vaccine match for influenza B decreased from approximately 100% to 33-54% in both hemispheres (P<0.05), following the unexpected resurgence of influenza B/Victoria in 1997. No estimate was available for influenza A/H1N1. We conclude that semi-annual vaccine recommendations are useful overall and discuss potential ways forward.
Copyright ? 2010. Published by Elsevier Ltd.
PMID: 20153352 [PubMed - as supplied by publisher]
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11. Vaccine. 2010 Feb 10. [Epub ahead of print]
Evaluation of Southern Hemisphere influenza vaccine recommendations.
Richard SA, Viboud C, Miller MA. - Fogarty International Center, National Institutes of Health, Bethesda, MD, United States.
In 1999, the World Health Organization switched from annual to semi-annual recommendations for influenza vaccine composition. We compared the antigenic match between recommendations and circulating viruses before and after 1999. Vaccine match proportion for A/H3N2 viruses increased from 31% to 59% in the Southern Hemisphere (P<0.05), and is now comparable to that in the Northern Hemisphere. Vaccine match for influenza B decreased from approximately 100% to 33-54% in both hemispheres (P<0.05), following the unexpected resurgence of influenza B/Victoria in 1997. No estimate was available for influenza A/H1N1. We conclude that semi-annual vaccine recommendations are useful overall and discuss potential ways forward.
Copyright ? 2010. Published by Elsevier Ltd.
PMID: 20153352 [PubMed - as supplied by publisher]
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