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Vaccine. Estimating the influenza vaccine effectiveness in elderly on a yearly basis using the Spanish influenza surveillance network-Pilot case-contr

Giuseppe

Emeritus
Estimating the influenza vaccine effectiveness in elderly on a yearly basis using the Spanish influenza surveillance network-Pilot case-control studies using different control groups, 2008-2009 season, Spain. (Vaccine, abstract, edited)

12. Vaccine. 2010 Feb 10. [Epub ahead of print]

Estimating the influenza vaccine effectiveness in elderly on a yearly basis using the Spanish influenza surveillance network-Pilot case-control studies using different control groups, 2008-2009 season, Spain.

Savulescu C, Valenciano M, de Mateo S, Larrauri A; the cycEVA Study Team. - European Centre for Disease Prevention and Control, European Program for Intervention Epidemiology Training, Stockholm, Sweden; Institute of Health Carlos III, National Centre of Epidemiology, Madrid, Spain.

We conducted a case-control and screening method studies to estimate influenza vaccine effectiveness (IVE) in the age group >=65 years, based on the Spanish Influenza Sentinel Surveillance System (SISSS). Cases (influenza laboratory-confirmed) were compared to influenza-negative ILI patients (test-negative) and patients without ILI since the beginning of the season (non-ILI). For the screening method, cases' vaccination coverage was compared to the vaccination coverage of the GPs' catchment population. The results suggested a protective effect of the vaccine against laboratory-confirmed influenza in elderly in 2008-2009. The screening method and the test-negative control designs enable estimating IVE using exclusively SISSS data.

Copyright ? 2010. Published by Elsevier Ltd.

PMID: 20153351 [PubMed - as supplied by publisher]
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