tetano
Editor, Senior Moderator
Vaccine
. 2022 Oct 31;S0264-410X(22)00766-6.
doi: 10.1016/j.vaccine.2022.06.018. Online ahead of print.
Effectiveness estimates for enhanced trivalent influenza vaccines in an aged care summer outbreak
Mohana Kunasekaran[SUP] 1 [/SUP], Aye Moa[SUP] 2 [/SUP], Elmira Hooshmand[SUP] 2 [/SUP], Mallory Trent[SUP] 2 [/SUP], Christopher J Poulos[SUP] 3 [/SUP], Abrar A Chughtai[SUP] 4 [/SUP], David J Heslop[SUP] 4 [/SUP], C Raina MacIntyre[SUP] 2 [/SUP]
Affiliations
Abstract
An influenza outbreak occurred during summer (February 2019) in an aged-care facility in Sydney, Australia. Residents had not received the annual 2019 influenza vaccine while 76.7% had received 2018 influenza vaccines about 9 months prior. Overall, 2018 influenza vaccine effectiveness during this outbreak was high (93.6%). The effectiveness of the high-dose trivalent vaccine (HD-TIV) and adjuvanted trivalent (a-TIV) vaccine were 89.8% (95% confidence interval: 18.8%-98.7%) and 72.5% (95% confidence interval: -106.7%-96.3%) respectively. The differences in effectiveness between HD-TIV, a-TIV and SD-QIV, during the summer outbreak were not significant.
Keywords: Adjuvanted trivalent vaccines; Aged care; High-dose trivalent vaccine; Influenza; Outbreak.
. 2022 Oct 31;S0264-410X(22)00766-6.
doi: 10.1016/j.vaccine.2022.06.018. Online ahead of print.
Effectiveness estimates for enhanced trivalent influenza vaccines in an aged care summer outbreak
Mohana Kunasekaran[SUP] 1 [/SUP], Aye Moa[SUP] 2 [/SUP], Elmira Hooshmand[SUP] 2 [/SUP], Mallory Trent[SUP] 2 [/SUP], Christopher J Poulos[SUP] 3 [/SUP], Abrar A Chughtai[SUP] 4 [/SUP], David J Heslop[SUP] 4 [/SUP], C Raina MacIntyre[SUP] 2 [/SUP]
Affiliations
- PMID: 36328885
- DOI: 10.1016/j.vaccine.2022.06.018
Abstract
An influenza outbreak occurred during summer (February 2019) in an aged-care facility in Sydney, Australia. Residents had not received the annual 2019 influenza vaccine while 76.7% had received 2018 influenza vaccines about 9 months prior. Overall, 2018 influenza vaccine effectiveness during this outbreak was high (93.6%). The effectiveness of the high-dose trivalent vaccine (HD-TIV) and adjuvanted trivalent (a-TIV) vaccine were 89.8% (95% confidence interval: 18.8%-98.7%) and 72.5% (95% confidence interval: -106.7%-96.3%) respectively. The differences in effectiveness between HD-TIV, a-TIV and SD-QIV, during the summer outbreak were not significant.
Keywords: Adjuvanted trivalent vaccines; Aged care; High-dose trivalent vaccine; Influenza; Outbreak.