tetano
Editor, Senior Moderator
Vaccine
. 2021 Jan 22;S0264-410X(20)31672-8.
doi: 10.1016/j.vaccine.2020.12.075. Online ahead of print.
Economic burden of influenza illness among children under 5 years in Suzhou, China: Report from the cost surveys during 2011/12 to 2016/17 influenza seasons
Yin Wang[SUP] 1 [/SUP], Liling Chen[SUP] 2 [/SUP], Fangfang Cheng[SUP] 3 [/SUP], Matthew Biggerstaff[SUP] 4 [/SUP], Sujian Situ[SUP] 5 [/SUP], Suizan Zhou[SUP] 4 [/SUP], Junmei Gao[SUP] 6 [/SUP], Changpeng Liu[SUP] 6 [/SUP], Jun Zhang[SUP] 2 [/SUP], Alexander J Millman[SUP] 4 [/SUP], Tao Zhang[SUP] 6 [/SUP], Jianmei Tian[SUP] 7 [/SUP], Genming Zhao[SUP] 8 [/SUP]
Affiliations
Abstract
Background: Data are limited on the economic burden of seasonal influenza in China. We estimated the cost due to influenza illness among children < 5-year-old in Suzhou, China.
Methods: This study adopted a societal perspective to estimate direct medical cost, direct non-medical cost, and indirect cost related to lost productivity. Data to calculate costs and rates of three influenza illness outcomes (non-medically attended, outpatient and hospitalization) were collected from prospective community-based cohort studies and hospital-based enhanced laboratory-confirmed influenza surveillance in Suzhou during the 2011/12 to 2016/17 influenza seasons. We used mean cost-per-episode, annual incidence rates of episodes of each outcome, and annual population size to estimate the total annual economic burden of influenza illnesses among children < 5-year-old for Suzhou. All costs were reported in 2017 U.S. dollars.
Results: The mean cost-per-episode (standard deviation) was $9.92 (13.26) for non-medically attended influenza, $161.05 (176.98) for influenza outpatient illnesses, and $1425.95 (603.59) for influenza hospitalizations. By applying the annual incidence rates to the population size, we estimated an annual total of 4,919 episodes of non-medically attended influenza, 21,994 influenza outpatient, and 2,633 influenza hospitalization. Total annual economic burden of influenza to society among children < 5-year-old in Suzhou was $7.37 (95% confidence interval, 6.9-7.8) million, with estimated costs for non-medically attended influenza of $49,000 (46,000-52,000), influenza outpatients $3.5 (3.3-3.8) million, and influenza hospitalizations $3.8 (3.6-3.9) million. Among outpatients, the indirect cost was 36.3% ($1.3 million) of total economic burden, accounting for 21,994 days of lost productivity annually. Among inpatients, the indirect cost was 22.1% ($829,000), accounting for 18,431 days of lost productivity annually.
Conclusions: Our findings show that influenza in children < 5-year-oldcauses substantial societal economic burden in Suzhou, China. Assessing the potential economic benefit of increasing influenza vaccination coverage in this population is warranted.
Keywords: Children; China; Direct cost; Economic burden; Indirect cost; Influenza.
. 2021 Jan 22;S0264-410X(20)31672-8.
doi: 10.1016/j.vaccine.2020.12.075. Online ahead of print.
Economic burden of influenza illness among children under 5 years in Suzhou, China: Report from the cost surveys during 2011/12 to 2016/17 influenza seasons
Yin Wang[SUP] 1 [/SUP], Liling Chen[SUP] 2 [/SUP], Fangfang Cheng[SUP] 3 [/SUP], Matthew Biggerstaff[SUP] 4 [/SUP], Sujian Situ[SUP] 5 [/SUP], Suizan Zhou[SUP] 4 [/SUP], Junmei Gao[SUP] 6 [/SUP], Changpeng Liu[SUP] 6 [/SUP], Jun Zhang[SUP] 2 [/SUP], Alexander J Millman[SUP] 4 [/SUP], Tao Zhang[SUP] 6 [/SUP], Jianmei Tian[SUP] 7 [/SUP], Genming Zhao[SUP] 8 [/SUP]
Affiliations
- PMID: 33494968
- DOI: 10.1016/j.vaccine.2020.12.075
Abstract
Background: Data are limited on the economic burden of seasonal influenza in China. We estimated the cost due to influenza illness among children < 5-year-old in Suzhou, China.
Methods: This study adopted a societal perspective to estimate direct medical cost, direct non-medical cost, and indirect cost related to lost productivity. Data to calculate costs and rates of three influenza illness outcomes (non-medically attended, outpatient and hospitalization) were collected from prospective community-based cohort studies and hospital-based enhanced laboratory-confirmed influenza surveillance in Suzhou during the 2011/12 to 2016/17 influenza seasons. We used mean cost-per-episode, annual incidence rates of episodes of each outcome, and annual population size to estimate the total annual economic burden of influenza illnesses among children < 5-year-old for Suzhou. All costs were reported in 2017 U.S. dollars.
Results: The mean cost-per-episode (standard deviation) was $9.92 (13.26) for non-medically attended influenza, $161.05 (176.98) for influenza outpatient illnesses, and $1425.95 (603.59) for influenza hospitalizations. By applying the annual incidence rates to the population size, we estimated an annual total of 4,919 episodes of non-medically attended influenza, 21,994 influenza outpatient, and 2,633 influenza hospitalization. Total annual economic burden of influenza to society among children < 5-year-old in Suzhou was $7.37 (95% confidence interval, 6.9-7.8) million, with estimated costs for non-medically attended influenza of $49,000 (46,000-52,000), influenza outpatients $3.5 (3.3-3.8) million, and influenza hospitalizations $3.8 (3.6-3.9) million. Among outpatients, the indirect cost was 36.3% ($1.3 million) of total economic burden, accounting for 21,994 days of lost productivity annually. Among inpatients, the indirect cost was 22.1% ($829,000), accounting for 18,431 days of lost productivity annually.
Conclusions: Our findings show that influenza in children < 5-year-oldcauses substantial societal economic burden in Suzhou, China. Assessing the potential economic benefit of increasing influenza vaccination coverage in this population is warranted.
Keywords: Children; China; Direct cost; Economic burden; Indirect cost; Influenza.