Giuseppe
Emeritus
Echinacea purpurea aerial extract alters course of influenza infection in mice. (Vaccine, abstract, edited)
[Source: US National Library of Medicine, (LINK). Edited.]
Vaccine. 2010 Apr 8. [Epub ahead of print]
Echinacea purpurea aerial extract alters course of influenza infection in mice.
Fusco D, Liu X, Salvatore M, Savage C, Taur Y, Xiao W, Kennelly E, Yuan J, Cassileth B, Papanicolaou G. - Division of Infectious Diseases, Weill Cornell Medical College, NY, United States.
Influenza infection is a major clinical problem and Echinacea purpurea, a widely consumed botanical product, is purported to alter the course of respiratory infections including influenza. Mice infected with WSN influenza A and treated with E. purpurea polysaccharide extract had less weight loss than untreated mice but similar pulmonary viral titers. Echinacea-treated mice had lower systemic and pulmonary KC and IL-10 levels and lower systemic IFN-gamma levels following influenza infection. These suggest that E. purpurea alters the clinical course of influenza infection in mice through modulation of cytokines and not direct antiviral activity.
Copyright ? 2010. Published by Elsevier Ltd.
PMID: 20382242 [PubMed - as supplied by publisher]
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[Source: US National Library of Medicine, (LINK). Edited.]
Vaccine. 2010 Apr 8. [Epub ahead of print]
Echinacea purpurea aerial extract alters course of influenza infection in mice.
Fusco D, Liu X, Salvatore M, Savage C, Taur Y, Xiao W, Kennelly E, Yuan J, Cassileth B, Papanicolaou G. - Division of Infectious Diseases, Weill Cornell Medical College, NY, United States.
Influenza infection is a major clinical problem and Echinacea purpurea, a widely consumed botanical product, is purported to alter the course of respiratory infections including influenza. Mice infected with WSN influenza A and treated with E. purpurea polysaccharide extract had less weight loss than untreated mice but similar pulmonary viral titers. Echinacea-treated mice had lower systemic and pulmonary KC and IL-10 levels and lower systemic IFN-gamma levels following influenza infection. These suggest that E. purpurea alters the clinical course of influenza infection in mice through modulation of cytokines and not direct antiviral activity.
Copyright ? 2010. Published by Elsevier Ltd.
PMID: 20382242 [PubMed - as supplied by publisher]
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