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Vaccine: Corrigendum to ?Immunological priming induced by a two-dose series of H5N1 influenza antigen, administered alone or in combination with two d

tetano

Editor, Senior Moderator
Vaccine

Volume 31, Issue 2, 2 January 2013, Pages 436?437
Cover image
Corrigendum
Corrigendum to ?Immunological priming induced by a two-dose series of H5N1 influenza antigen, administered alone or in combination with two different formulations of AS03 adjuvant in adults: Results of a randomised single heterologous booster dose study at 15 months? [Vaccine 29 (2011) 6408?6418]

George Risia, Corresponding author contact information, E-mail the corresponding author,
Louise Frenetteb,
Joanne M. Langleyc,
Ping Lid,
Dennis Riffe,
Eric Sheldonf,
David W. Vaughnd,
Louis Friesg

a Infectious Disease Specialists, P.C., 614 West Spruce Street, Missoula, MT 59802, United States
b QT Research, Sherbrooke, Quebec, Canada
c Canadian Center for Vaccinology, Dalhousie University and IWK Health Centre Halifax, Halifax, Canada
d GlaxoSmithKline Biologicals, King of Prussia, PA, United States
e Clinical Research Institute, Anaheim, CA, United States
f Miami Research Associates, Miami, FL, United States
g GlaxoSmithKline, Columbia, MD, United States

http://dx.doi.org/10.1016/j.vaccine.2012.11.002, How to Cite or Link Using DOI

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George Risi, Louise Frenette, Joanne M. Langley, Ping Li, Dennis Riff, Eric Sheldon, David W. Vaughn, Louis Fries
Immunological priming induced by a two-dose series of H5N1 influenza antigen, administered alone or in combination with two different formulations of AS03 adjuvant in adults: Results of a randomised single heterologous booster dose study at 15 months
Vaccine, Volume 29, Issue 37, 26 August 2011, Pages 6408-6418
PDF (455 K)

In volume 29 (2011) of Vaccine we reported on the safety and immunogenicity of heterologous boosting with AS03-adjuvanted or non-adjuvanted A/turkey/Turkey/1/2005 (H5N1) vaccines 14 months following two-dose priming with AS03-adjuvanted or non-adjuvanted A/Indonesia/5/2005 (H5N1) vaccines. Table 1 (p. 6413) of that publication summarised immune responses in terms of hemagglutinating antibody to support the study primary objectives. Table 3 on p. 6415 presented neutralising antibody responses to A/turkey/Turkey/1/2005 (H5N1), A/Indonesia/5/2005 (H5N1), and A/Vietnam/1194/2004 (H5N1). Following publication, an assay specificity issue was recognised for the A/Vietnam/1194/2004 microneutralisation (MN) assay for study Days 0, 10, and 42. Results from repeat testing for those days are reported here.

Previously reported data, corrected results (in yellow), and measures of change (in blue) for Days 0, 10, and 42 MN titres for A/Vietnam/1194/2004 (H5N1) are shown in the below table along with unchanged Day 182 results based on testing performed after the specificity issue had been addressed.

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http://www.sciencedirect.com/science/article/pii/S0264410X12015940
 
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