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Utility of state-level influenza disease burden and severity estimates to investigate an apparent increase in reported severe cases of influenza A(H1N

tetano

Editor, Senior Moderator
Epidemiol Infect. 2018 Jun 14:1-7. doi: 10.1017/S0950268818001516. [Epub ahead of print]
[h=1].[/h] Russell K[SUP]1[/SUP], Herrick K[SUP]2[/SUP], Venkat H[SUP]1[/SUP], Brady S[SUP]2[/SUP], Komatsu K[SUP]2[/SUP], Goodin K[SUP]3[/SUP], Berisha V[SUP]3[/SUP], Sunenshine R[SUP]3[/SUP], Perez-Velez C[SUP]4[/SUP], Elliott S[SUP]5[/SUP], Olsen SJ[SUP]6[/SUP], Reed C[SUP]6[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] The Arizona Department of Health Services identified unusually high levels of influenza activity and severe complications during the 2015-2016 influenza season leading to concerns about potential increased disease severity compared with prior seasons. We estimated state-level burden and severity to compare across three seasons using multiple data sources for community-level illness, hospitalisation and death. Severity ratios were calculated as the number of hospitalisations or deaths per community case. Community influenza-like illness rates, hospitalisation rates and mortality rates in 2015-2016 were higher than the previous two seasons. However, ratios of severe disease to community illness were similar. Arizona experienced overall increased disease burden in 2015-2016, but not increased severity compared with prior seasons. Timely estimates of state-specific burden and severity are potentially feasible and may provide important information during seemingly unusual influenza seasons or pandemic situations.


[h=4]KEYWORDS:[/h] Epidemiology; estimating disease prevalence; influenza; outbreaks; pandemic

PMID: 29898797 DOI: 10.1017/S0950268818001516
 
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