USA - H3N2 swine flu in 2 human cases, "vicinity" of pigs cited - CDC

[tetano]

Chapter Роспотребнадзора, the main state health officer of the Russian Federation Gennady Onishchenko has declared press, that the Russian physicians have obtained data about occurrence in the world of a new virus of a flu.

' We have received the message - guarding information on system of the notification of the Worldwide organization of healthcare - that in the USA at two person is allocated virus H3N2 ', - has told Онищенко.
As he said, the new virus is a mutation of a pork flu. ' It will consist of three slices of former viruses.
But it another on genetic structure ', - has told Онищенко, having answered, that now in department study this information. As he said, the first case of a new flu is fixed at the 7-month's child in the USA in Illinois, the second - at 46-years men in Pennsylvania.

According to the main health officer, in Russia the situation with a flu and sharp respiratory diseases now does not cause alarm. Desease in all Russian regions, including cities-миллионники, is below epidemic thresholds, marks Утро.ру.

Earlier physicians have stated fear in occasion of possible crossing pork flu H1N1 with a virus of bird's flu H5N1. According to the main health officer of the Russian Federation, physicians very steadfastly track these processes. Онищенко also has noticed, that H5N1 - a virus the extremely changeable.

http://kurskweb.ru/news/country/15307.html

 

[curiosity]

Re: Оnnishenko: H3N2 Notice

Re: Оnnishenko: H3N2 Notice

Article Translated from Russian Text using Google

Article Link


In the U.S., revealed a new "swine" virus
To
November 10, 2010 19:34

Delfi Pilt
Russian doctors have received information about the appearance in the world of a new influenza virus. "We have received a message through the paging system of the World Health Organization that the United States for two people the virus H3N2, - said the head of Rospotrebnadzor, the chief sanitary doctor Gennady Onishchenko. - This mutation Influenza swine origin.


Gennady Onishchenko said that the new flu is a triple-reassortant - it consists of just three viruses that had previously been circulated, the agency Interfax.


"It consists of three" pieces "of the former viruses, but it's different in genetic structure. We are studying this information," - he said. Earlier, doctors said that the swine flu outbreak in the Northern Hemisphere, which was awarded last autumn-winter period, has remained a dangerous mutation.

According to Onishchenko, the first of a new flu detected in 7-month-old baby in the U.S. state of Illinois, the second - a 46-year-old man in Pennsylvania. Chief State Sanitary Doctor of Russia said that Russian doctors will ask the U.S. experts about the new virus.

 

[curiosity]

Re: Оnnishenko: H3N2 Notice

Re: Оnnishenko: H3N2 Notice

Translated from Russian to English with Google:

Article Link

Ukrainian Health Ministry is not worried about the new flu
"Gazeta po - Kiev, 10.11.2010 Yesterday all ministries of health of the world have received through the paging system of the World Health Organization information on registration in the United States a new strain of swine flu virus.

WHO has identified the two Americans virus H3N2: one of them - the seven-month child (Illinois), and the second - a man of forty-six years old from Pennsylvania.

According to the chief sanvracha Russia Gennady Onishchenko, the new influenza virus is a triple-reassortant, ie it consists of just three known previously functioning, the virus:

- H3N2 has always been a seasonal influenza strain, like H1N1. Another thing is that in two cases of Americans examined this strain and isolated, it is the same H3N2, but mutated, reasortantny consisting of the three strains.

It turns out that the genetic structure of H3N2 is different from the "precursor" and it's hard to say how he will behave. Earlier, doctors said that the swine flu has not undergone any major mutations.

The Health Ministry of Ukraine reacted to information about the new mutant strain of calm.

- This strain is predicted this year. Special means to deal with it as normal seasonal influenza, is not provided. Under the H1N1 virus they identified as an exception, - the press service of the Ministry of Health.

In the Ukrainian Center for Influenza assured that they are ready for any virus and tools to deal with him plenty, but still too early to worry.

 

[curiosity]

Re: Оnnishenko: H3N2 Notice

Re: Оnnishenko: H3N2 Notice

Translated from Russian to English using Google:

Article Link

Russian doctors asked the U.S. about the new influenza virus

New influenza virus detected in the U.S., will not lead to a global epidemic. This opinion was expressed by the chief physician of Russia Alexander Chuchalin. "There are no data that we will meet with an unusual new infections of the respiratory tract, no" - said Chuchalin.

Earlier, the chief sanitary doctor Gennady Onishchenko said that in the United States two people isolated a new virus H3N2. This mutation Influenza swine origin. New flu is directly from the three viruses that had previously been circulated. Russian doctors have asked my American colleagues about the new strain.

 

[sharon sanders]

Re: USA - H3N2 genetic change? Gennadiy Onishchenko - Health Officer of Russia says yes

Re: USA - H3N2 genetic change? Gennadiy Onishchenko - Health Officer of Russia says yes

Also please see:

Puerto Rico - H3N2 is the dominant variant of the virus this year October 2010

CDC Health Advisory - Seasonal Influenza A (H3N2) Virus Infections - August 2010

The Government confirmed a new H3N2 variant of influenza virus is endemic in Hong Kong - August 2009

 

[Giuseppe]

Re: USA - H3N2 genetic change? Gennadiy Onishchenko - Health Officer of Russia says yes

Re: USA - H3N2 genetic change? Gennadiy Onishchenko - Health Officer of Russia says yes

From MMWR Morb Mortal Wkly Rep. http://www.cdc.gov/mmwr/PDF/wk/mm5944.pdf

(???) CDC discontinued reporting of individual confirmed and probable cases of 2009 pandemic influenza A (H1N1) virus infections on July 24, 2009. During 2009, four cases of human infection with novel influenza A viruses, different from the 2009 pandemic influenza A (H1N1) strain, were reported to CDC.

The two cases of novel influenza A virus infection reported to CDC during 2010 were identified as swine influenza A (H3N2) virus and are unrelated to the 2009 pandemic influenza A (H1N1) virus.

Total case counts for 2009 were provided by the Influenza Division, National Center for Immunization and Respiratory Diseases (NCIRD).

------

 

[alert]

Re: USA - H3N2 genetic change? Gennadiy Onishchenko - Health Officer of Russia says yes

Re: USA - H3N2 genetic change? Gennadiy Onishchenko - Health Officer of Russia says yes

I think I agree with ironorehopper - this seems to be the report of the swine H3N2 infections, not a seasonal flu virus, especially in light of the mention of "Pennsylvania" in the Russian articles, which is where the above table puts the new infection.

Hopefully these are just pig-to-human infections that do not lead to further spread.

More information on the makeup of this H3N2 (and whether the cases in Illinois and Pennsylvania match - the Russian articles seem to imply they do) would be helpful.

 

[alert]

Re: USA - H3N2 genetic change? Gennadiy Onishchenko - Health Officer of Russia says yes

Re: USA - H3N2 genetic change? Gennadiy Onishchenko - Health Officer of Russia says yes

The link below is the week 23 MMWR, for week ending June 18, 2010, and already contains the first novel influenza detection (and the week 22 one does not), but does not indicate where it occurred (presumably Illinois) and does not list it as current week.

Ironorehopper's week 44 MMWR above is the first report with the second detection. IMO, the five months gap makes the ongoing person-to-person spread of this virus unlikely; we would have had more than two detections by now.

http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5923md.htm?s_cid=mm5923md_w

 

[curiosity]

Re: USA - H3N2 genetic change? Gennadiy Onishchenko - Health Officer of Russia says yes

Re: USA - H3N2 genetic change? Gennadiy Onishchenko - Health Officer of Russia says yes

I think you are both right, but in the report above, Onishchenko remarks they are notified via a "paging" system of the WHO - If it is true, why would the MMWR information be "paged?"

posted above: "We have received a message through the paging system of the World Health Organization that the United States for two people the virus H3N2," - said the head of Rospotrebnadzor, the chief sanitary doctor Gennady Onishchenko.

 

[alert]

Re: USA - H3N2 genetic change? Gennadiy Onishchenko - Health Officer of Russia says yes

Re: USA - H3N2 genetic change? Gennadiy Onishchenko - Health Officer of Russia says yes

The IHR regulations below state that the detection of a novel strain of influenza is one of four diseases (SARS, smallpox, and polio being the other three) that require immediate notification of the WHO.

The US CDC likely filed such a notification.

http://www.who.int/ihr/Case_Definitions.pdf

 

[alert]

Re: USA - H3N2 genetic change? Gennadiy Onishchenko - Health Officer of Russia says yes

Re: USA - H3N2 genetic change? Gennadiy Onishchenko - Health Officer of Russia says yes

http://kp.ua/daily/111110/252618/

[snip]

Meanwhile, the World Health Organization reports that the world has a new influenza virus - H3N2. It consists of three previously known strains of influenza. Already registered two cases of such flu - a seven-month baby and a 46-year-old man in the U.S..

 

[alert]

Re: USA - H3N2 genetic change? Gennadiy Onishchenko - Health Officer of Russia says yes

Re: USA - H3N2 genetic change? Gennadiy Onishchenko - Health Officer of Russia says yes

http://www.molgvardia.ru/nextday/2010/11/10/20594

Russians can not be afraid of influenza bacilli mutants
Wednesday, November 10, 2010 - 18:34 / 36 views
World Health Organization is trying to provoke another "grunting hysteria." Ostensibly, the virus of swine flu mutated and returned. Gennady Onishchenko, has assured the Russians that the risk of influenza H3N2 is not for them, but experts are closely watching the spread of new virus.

"Pig panic" has played in the first place, into the hands of drug manufacturers. And now - the next round of global fear of sickness. Paging system, WHO, Rospotrebnadzor got a message saying that the U.S. two people the virus H3N2.

Gennady Onishchenko said that this mutation Influenza swine origin. New flu, he said, is a triple-reassortant - is at once the three viruses that had previously been circulated, but differs from them in the genetic structure. Russian doctors ask their American colleagues for details about the new virus.

While H3N2 virus detected in the seven-month baby in the U.S. state of Illinois and a 46-year-old man in Pennsylvania. Center for Disease Control and Prevention U.S. asks people to pass routine vaccination of influenza virus B, H1N1 and H3N2. Nevertheless, Americans still do not panic.

 

[alert]

Re: USA - H3N2 genetic change? Gennadiy Onishchenko - Health Officer of Russia says yes

Re: USA - H3N2 genetic change? Gennadiy Onishchenko - Health Officer of Russia says yes

The bold text might give us some kind of indication of the makeup of this virus.

http://www.radiomayak.ru/doc.html?id=209595

New influenza virus detected in the U.S., will not lead to a global epidemic. This opinion was expressed by the chief physician of Russia Alexander Chuchalin. "Data that we will meet with an unusual new infections of the respiratory tract, no" - he said.

Earlier, the chief sanitary doctor Gennady Onishchenko said that in the United States two people isolated a new virus H3N2. This mutation Influenza swine origin. New flu is directly from the three viruses that had previously been circulated. Russian doctors asked my American colleagues about the new strain.

 

[sharon sanders]

Re: USA - H3N2 genetic change? Gennadiy Onishchenko - Health Officer of Russia says yes

Re: USA - H3N2 genetic change? Gennadiy Onishchenko - Health Officer of Russia says yes

The bold text might give us some kind of indication of the makeup of this virus.

http://www.radiomayak.ru/doc.html?id=209595

New influenza virus detected in the U.S., will not lead to a global epidemic. This opinion was expressed by the chief physician of Russia Alexander Chuchalin. "Data that we will meet with an unusual new infections of the respiratory tract, no" - he said.

Earlier, the chief sanitary doctor Gennady Onishchenko said that in the United States two people isolated a new virus H3N2. This mutation Influenza swine origin. New flu is directly from the three viruses that had previously been circulated. Russian doctors asked my American colleagues about the new strain.

I think the Russian media is circulating the same story over and over in this news cycle.

I would like to see the text of the information about this event that Gennady Onishchenko is referring to.

 

[alert]

Re: USA - H3N2 genetic change? Gennadiy Onishchenko - Health Officer of Russia says yes

Re: USA - H3N2 genetic change? Gennadiy Onishchenko - Health Officer of Russia says yes

I think the Russian media is circulating the same story over and over in this news cycle.

I would like to see the text of the information about this event that Gennady Onishchenko is referring to.

Agreed.

 

[alert]

Re: USA - H3N2 genetic change? Gennady Onishchenko - Health Officer of Russia says yes

Re: USA - H3N2 genetic change? Gennady Onishchenko - Health Officer of Russia says yes

http://www.19rus.ru/more.php?UID=28830

Russian to English translation
2010.11.11 15:17
Russians are the new H3N2 virus does not threaten
Independent News Agency - Khakassia



In the U.S., found a new version of "swine flu". H3N2 virus was detected in 7-month-old child in Illinois and a 46-year old resident of Pennsylvania. This strain has been known since 1998.
Chief sanitary doctor Gennady Onishchenko said that the virus is recorded in the U.S., the Russians are not in danger, - transmits RBC.
Speaking to reporters, Gennady Onishchenko, said that the Federal Service closely monitors all the information about the new disease. He urged Russians to remain calm and not panic. "We've got it (the virus), fortunately, no, but we are watching him," - he said.

 

[gsgs]

Re: USA - H3N2 genetic change? Gennady Onishchenko - Health Officer of Russia says yes

Re: USA - H3N2 genetic change? Gennady Onishchenko - Health Officer of Russia says yes

so "triple-reassortant" could just refer to the US-swine virus which emerged in 1998
and since then circulates in US-swine (and turkey-farms),
reassorting with other swine-viruses, so it appears a H1N1--(Mx)
or H3N2(original) or H1N2 besides occasional other variants -
I remember H3N1 or H2N3.

We had 10-20 such events since 1998 where this strain crossed
to humans or created new serotypes in swine.

OTOH it could also be an entirely new recent virus
3 fold reassorted, at least one of the parts presumably
being that "triple-swine-reassortant-1998"-strain,
one other part maybe Mx ?

my guess is, it's the former.

That H3 diverged from human H3N2 from the 90s,
so we do have some immunity, not a "pandemic",
only a new substrain.

 

[Gert van der Hoek]

Re: USA - H3N2 genetic change? Gennady Onishchenko - Health Officer of Russia says yes

Re: USA - H3N2 genetic change? Gennady Onishchenko - Health Officer of Russia says yes

so "triple-reassortant" could just refer to the US-swine virus which emerged in 1998
and since then circulates in US-swine (and turkey-farms),
reassorting with other swine-viruses, so it appears a H1N1--(Mx)
or H3N2(original) or H1N2 besides occasional other variants -
I remember H3N1 or H2N3.

We had 10-20 such events since 1998 where this strain crossed
to humans or created new serotypes in swine.

OTOH it could also be an entirely new recent virus
3 fold reassorted, at least one of the parts presumably
being that "triple-swine-reassortant-1998"-strain,
one other part maybe Mx ?

my guess is, it's the former.

That H3 diverged from human H3N2 from the 90s,
so we do have some immunity, not a "pandemic",
only a new substrain.

May be you refer to :

H3N2 Influenza Virus Transmission from Swine to Turkeys, United States


"In 1998, a novel H3N2 reassortant virus emerged in
the United States swine population".

"The isolation of swine-like H3N2
influenza viruses from turkeys raises new concerns for the
generation of novel viruses that could affect humans".

Link to full report - PDF

 

[Missouriwatcher]

Re: USA - H3N2 genetic change? Gennady Onishchenko - Health Officer of Russia says yes

Re: USA - H3N2 genetic change? Gennady Onishchenko - Health Officer of Russia says yes

The first reference to the swine influenza A (H3N2) for this year was in the MMWR (June 18, 2010) week 23:

"...During 2009, three cases of novel influenza A virus infections, unrelated to the 2009 pandemic influenza A (H1N1) virus, were reported to CDC. The one case of novel influenza A virus infection reported to CDC during 2010 was identified as swine influenza A (H3N2) virus and is unrelated to pandemic influenza A (H1N1) virus."

The case was not detected in week 23, just reported, and the state not identified.
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5923md.htm?s_cid=mm5923md_w

Then, in week 39 (2010), MMWR subscript read:
"...During 2009, four cases of human infection with novel influenza A viruses, different from the 2009 pandemic influenza A (H1N1) strain, were reported to CDC..." http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5939md.htm?s_cid=mm5939md_w

Current MMWR:
"...During 2009, four cases of human infection with novel influenza A viruses, different from the 2009 pandemic influenza A (H1N1) strain, were reported to CDC. The two cases of novel influenza A virus infection reported to CDC during 2010 were identified as swine influenza A (H3N2) virus and are unrelated to the 2009 pandemic influenza A (H1N1) virus..."
http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5944md.htm?s_cid=mm5944md_w

 

[sharon sanders]

Re: USA - H3N2 genetic change? Gennady Onishchenko - Health Officer of Russia says yes

Re: USA - H3N2 genetic change? Gennady Onishchenko - Health Officer of Russia says yes

Thanks everyone.

Flu strains are always changing. This is not new.

My question is how close a match is the H3N2 "like" [A/Brisbane/10/2007 and A/Uruguay/716/2007 (an A/Brisbane/10/2007-like virus)] component in the current northern hemisphere trivalent vaccine to the genetics of the H3N2 referenced in the 2 US cases above?