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USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-38: 108 Total Pediatric Deaths

Re: USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-10: 3 New Pediatric Deaths, 68 Total

Re: USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-10: 3 New Pediatric Deaths, 68 Total

Wk 10, ending Mar 8

Influenza-Associated Pediatric Mortality
Three influenza-associated pediatric deaths were reported to CDC during week 10. Two deaths were associated with a 2009 H1N1 virus and occurred during weeks 52 and 7 (weeks ending December 28, 2013 and February 15, 2014). One death was associated with an influenza A virus for which no subtyping was performed and occurred during week 6 (week ending February 1, 2014). From MMWR: ME (1), IL (1), MD (1)


A total of 68 influenza-associated pediatric deaths have been reported during the 2013-2014 season from Chicago [1], New York City [1] and 28 states (AR [4], AZ [1], CA [6]; FL [3], GA [1]; IA [1]; IL [1]; KS [2], KY [1]; LA [5]; MA [2]; MD [1]; ME [1]; MI [2], MS [1], NC [5]; NE [1], NV [1], OK [2]; OR [1], PA [1], SC [2], TN [4]; TX [11]; UT [2]; VA [1]; WI [1]; and WV [2]).

Influenza-associated Hospitalizations:
Between October 1, 2013 and March 8, 2014, 7,910 laboratory-confirmed influenza-associated hospitalizations were reported. This is a rate of 29.2 per 100,000 population. The highest rate of hospitalization remains among adults aged ≥65 years, followed by the 50-64 years and 0-4 years age groups. People 18-64 years accounted for more than 60% of reported hospitalized cases. Among all hospitalizations, 7,434 (94.0%) were associated with influenza A, 397 (5.0%) with influenza B, 29 (0.4%) with influenza A and B co-infection, and 50 (0.6%) had no virus type information. Among those with influenza A subtype information, 77 (2.2%) were H3 and 3,415 (97.8%) were 2009 H1N1.

Clinical findings are preliminary and based on approximately 44% of cases with complete medical chart abstraction. The most commonly reported underlying medical conditions among adults were obesity, metabolic disorders, cardiovascular disease, and chronic lung disease (excluding asthma). Approximately 12% of hospitalized adults had no identified underlying medical conditions. The most commonly reported underlying medical conditions in children were asthma, neurologic disorders, obesity, cardiovascular disease, and chronic lung disease (excluding asthma). Approximately 44% of hospitalized children had no identified underlying medical conditions. Among 486 hospitalized women of childbearing age (15-44 years), 104 (21.4%) were pregnant.

U.S. Virologic Surveillance
No. of specimens tested: 6,372
No. of positive specimens (%): 535 (8.4%)
Positive specimens by type/subtype
Influenza A: 362 (67.7%)
2009 H1N1: 153 (42.3%)
H3: 31 (8.6%)
Subtyping not performed: 178 (49.2%)
Influenza B: 173 (32.3%)

Neuraminidase Inhibitor Resistance Testing Results Since Oct 1, 2013
2009 H1N1: 4155 tested, 40 (1.0%) are resistant
All other samples tested found 0 resistant

Antigenic Characterization*
CDC has antigenically characterized 1,668 influenza viruses [1,415 2009 H1N1 viruses, 170 influenza A (H3N2) viruses, and 83 influenza B viruses] collected by U.S. laboratories since October 1, 2013 by hemagglutination inhibition (HI).

2009 H1N1 [1,415]:
1,414 (99.9%) of 1,415 2009 H1N1 viruses tested were characterized as A/California/7/2009-like, the influenza A (H1N1) component of the 2013-2014 Northern Hemisphere influenza vaccine. One (0.1%) virus showed reduced titers with antiserum produced against A/California/7/2009.

Influenza A (H3N2) [170]:
All 170 influenza A (H3N2) viruses tested have been characterized as A/Texas/50/2012-like, the influenza A (H3N2) component of the 2013-2014 Northern Hemisphere influenza vaccine.

Influenza B [83]: 53 (64%) of the 83 influenza B viruses tested belong to B/Yamagata/16/88-lineage and the remaining 30 (36%) influenza B viruses tested belong to B/Victoria/02/87 lineage.
Yamagata Lineage [53]: 53 influenza B/Yamagata-lineage viruses were characterized as B/ Massachusetts/2/2012-like, which is included as an influenza B component of the 2013-2014 Northern Hemisphere trivalent and quadrivalent influenza vaccines.
Victoria Lineage [30]: 30 influenza B/Victoria-lineage viruses were characterized as B/Brisbane/60/2008-like, which is included as an influenza B component of the 2013-2014 Northern Hemisphere quadrivalent influenza vaccine.

Composition of the 2014-2015 Influenza Vaccine
The World Health Organization (WHO) has recommended vaccine viruses for the 2014-2015 Northern Hemisphere vaccines, and the Food and Drug Administration’s Vaccines and Related Biological Products Advisory Committee (VRBPAC) has made recommendations for the composition of the 2014-2015 influenza vaccines to be used in the United States. Both agencies recommend that trivalent vaccines contain an A/California/7/2009-like (2009 H1N1) virus, an A/Texas/50/2012-like (H3N2) virus, and a B/Massachusetts/2/2012-like (B/Yamagata lineage) virus. It is recommended that quadrivalent vaccines containing an additional influenza B virus contain a B/Brisbane/60/2008-like (B/Victoria lineage) virus in addition to the viruses recommended for the trivalent vaccines. These recommendations were based on global influenza virus surveillance data related to epidemiology and antigenic characteristics, serological responses to 2013-2014 seasonal vaccines, and the availability of candidate strains and reagents.

http://www.cdc.gov/flu/weekly/
 
Re: USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-11: 7 New Pediatric Deaths, 75 Total

Re: USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-11: 7 New Pediatric Deaths, 75 Total

Wk 11, ending Mar 15

Influenza-Associated Pediatric Mortality
Seven influenza-associated pediatric deaths were reported to CDC during week 11. One death was associated with a 2009 H1N1 virus and occurred during week 10 (week ending March 8, 2014) and five deaths were associated with an influenza A virus for which no subtyping was performed and occurred during weeks 49, 8, and 9 (weeks ending December 7, 2013, February 22 and March 1, 2014). One death was associated with an influenza B virus and occurred during week 10 (week ending March 8, 2014). From MMWR: Wk 11, ending Mar 15 = 7: PA (1), WI (1), FL (1), TX (3), CA (1)

A total of 75 influenza-associated pediatric deaths have been reported during the 2013-2014 season from Chicago [1], New York City [1] and 28 states (AR [4]; AZ [1]; CA [7]; FL [4]; GA [1]; IA [1]; IL [1]; KS [2]; KY [1]; LA [5]; MA [2]; MD [1]; ME [1]; MI [2]; MS [1]; NC [5]; NE [1]; NV [1]; OK [2]; OR [1]; PA [2]; SC [2]; TN [4]; TX [14]; UT [2]; VA [1]; WI [2]; and WV [2]).

Influenza-Associated Hospitalizations
Between October 1, 2013 and March 15, 2014, 8,235 laboratory-confirmed influenza-associated hospitalizations were reported. This is a rate of 30.4 per 100,000 population. The highest rate of hospitalization remains among adults aged ≥65 years, followed by the 50-64 years and 0-4 years age groups. People 18-64 years accounted for more than 60% of reported hospitalized cases. Among all hospitalizations, 7,703 (93.6%) were associated with influenza A, 446 (5.4%) with influenza B, 33 (0.4%) with influenza A and B co-infection, and 53 (0.6%) had no virus type information. Among those with influenza A subtype information, 98 (2.6%) were H3 and 3,606 (97.4%) were 2009 H1N1.

Clinical findings are preliminary and based on ~46% of cases with complete medical chart abstraction. The most commonly reported underlying medical conditions among adults were obesity, metabolic disorders, cardiovascular disease, and chronic lung disease (excluding asthma). Approximately 12% of hospitalized adults had no identified underlying medical conditions. The most commonly reported underlying medical conditions in children were asthma, neurologic disorders, obesity, and cardiovascular disease. Approximately 43% of hospitalized children had no identified underlying medical conditions. Among 530 hospitalized women of childbearing age (15-44 years), 117 (22.1%) were pregnant.

U.S. Virologic Surveillance
No. of specimens tested: 5650
No. of positive specimens: 495 (8.8%)
Positive specimens by type/subtype
Influenza A: 341 (68.9%)
2009 H1N1: 146 (42.8%)
H3: 46 (13.5%)
Subtyping not performed: 149 (43.7%)
Influenza B: 154 (31.3%)

Neuraminidase Inhibitor Resistance Testing Results Since Oct 1, 2013
2009 H1N1: 4413 tested, 43 (1.0%) are resistant
All other samples tested found 0 resistant

Antigenic Characterization*
CDC has antigenically characterized 1,854 influenza viruses [1,506 2009 H1N1 viruses, 225 influenza A (H3N2) viruses, and 123 influenza B viruses] collected by U.S. laboratories since October 1, 2013 by hemagglutination inhibition (HI).

2009 H1N1 [1,506]:
* 1,505 (99.9%) of 1,506 2009 H1N1 viruses tested were characterized as A/California/7/2009-like, the influenza A (H1N1) component of the 2013-2014 Northern Hemisphere influenza vaccine. One (0.1%) virus showed reduced titers with antiserum produced against A/California/7/2009.

Influenza A (H3N2) [225]:
* 224 (99.6%) of the 225 influenza A (H3N2) viruses tested have been characterized as A/Texas/50/2012-like, the influenza A (H3N2) component of the 2013-2014 Northern Hemisphere influenza vaccine. One (0.4%) virus showed reduced titers with antiserum produced against A/Texas/50/2012.

Influenza B [123]: 84 (68%) of the 123 influenza B viruses tested belong to B/Yamagata/16/88-lineage and the remaining 39 (32%) influenza B viruses tested belong to B/Victoria/02/87 lineage.
* Yamagata Lineage [84]: 84 influenza B/Yamagata-lineage viruses were characterized as B/ Massachusetts/2/2012-like, which is included as an influenza B component of the 2013-2014 Northern Hemisphere trivalent and quadrivalent influenza vaccines.
* Victoria Lineage [39]: 39 influenza B/Victoria-lineage viruses were characterized as B/Brisbane/60/2008-like, which is included as an influenza B component of the 2013-2014 Northern Hemisphere quadrivalent influenza vaccine.

http://www.cdc.gov/flu/weekly/
 
Re: USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-12: 4 New Pediatric Deaths, 79 Total

Re: USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-12: 4 New Pediatric Deaths, 79 Total

Wk 12, ending Mar 22

Influenza-Associated Pediatric Mortality
Four influenza-associated pediatric deaths were reported to CDC during week 12. From the MMWR: NYC (1), PA (1), TX (2)

One death was associated with a 2009 H1N1 virus and occurred during week 5 (week ending February 1, 2014) and two deaths were associated with influenza A viruses for which no subtyping was performed and occurred during weeks 6 and 12 (weeks ending February 8 and March 22, 2014). One death was associated with an influenza B virus and occurred during week 10 (week ending March 8, 2014).

A total of 79 influenza-associated pediatric deaths have been reported during the 2013-2014 season from Chicago [1], New York City [2] and 28 states (AR [4]; AZ [1]; CA [7]; FL [4]; GA [1]; IA [1]; IL [1]; KS [2]; KY [1]; LA [5]; MA [2]; MD [1]; ME [1]; MI [2]; MS [1]; NC [5]; NE [1]; NV [1]; OK [2]; OR [1]; PA [3]; SC [2]; TN [4]; TX [16]; UT [2]; VA [1]; WI [2]; and WV [2]).

Influenza-Associated Hospitalizations
Between October 1, 2013 and March 22, 2014, 8,405 laboratory-confirmed influenza-associated hospitalizations were reported. This is a rate of 31.1 per 100,000 population. The highest rate of hospitalization remains among adults aged ≥65 years, followed by the 50-64 year and 0-4 year age groups. People aged 18-64 years accounted for approximately 60% of reported hospitalized cases. Among all hospitalizations, 7,814 (93.0%) were associated with influenza A, 500 (5.9%) with influenza B, 37 (0.4%) with influenza A and B co-infection, and 55 (0.7%) had no virus type information. Among those with influenza A subtype information, 102 (2.7%) were H3 and 3,682 (97.3%) were 2009 H1N1.

Clinical findings are preliminary and based on approximately 50% of cases with complete medical chart abstraction. The most commonly reported underlying medical conditions among adults were obesity, metabolic disorders, cardiovascular disease, and chronic lung disease (excluding asthma). Approximately 12% of hospitalized adults had no identified underlying medical conditions. The most commonly reported underlying medical conditions in children were asthma, neurologic disorders, obesity, and chronic lung disease (excluding asthma). Approximately 43% of hospitalized children had no identified underlying medical conditions. Among 588 hospitalized women of childbearing age (15-44 years), 132 (22.4%) were pregnant.

U.S. Virologic Surveillance
No. of specimens tested: 4977
No. of positive specimens: 571 (11.5%)
Positive specimens by type/subtype
Influenza A: 348 (60.9%)
2009 H1N1: 101 (29.0%)
H3: 68 (19.5%)
Subtyping not performed: 179 (51.4%)
Influenza B: 223 (39.1%)

Neuraminidase Inhibitor Resistance Testing Results Since Oct 1, 2013
2009 H1N1: 4624 tested, 54 (1.2%) are resistant
All other samples tested found 0 resistant

Antigenic Characterization*
CDC has antigenically characterized 1,914 influenza viruses [1,562 2009 H1N1 viruses, 229 influenza A (H3N2) viruses, and 123 influenza B viruses] collected by U.S. laboratories since October 1, 2013 by hemagglutination inhibition (HI).

2009 H1N1 [1,562]:
* 1,561 (99.9%) of 1,562 2009 H1N1 viruses tested were characterized as A/California/7/2009-like, the influenza A (H1N1) component of the 2013-2014 Northern Hemisphere influenza vaccine. One (0.1%) virus showed reduced titers with antiserum produced against A/California/7/2009.

Influenza A (H3N2) [229]:
* 224 (97.8%) of the 229 influenza A (H3N2) viruses tested have been characterized as A/Texas/50/2012-like, the influenza A (H3N2) component of the 2013-2014 Northern Hemisphere influenza vaccine. Five (2.2%) viruses showed reduced titers with antiserum produced against A/Texas/50/2012.

Influenza B [123]: 84 (68%) of the 123 influenza B viruses tested belong to B/Yamagata/16/88-lineage and the remaining 39 (32%) influenza B viruses tested belong to B/Victoria/02/87 lineage.
* Yamagata Lineage [84]: 84 influenza B/Yamagata-lineage viruses were characterized as B/ Massachusetts/2/2012-like, which is included as an influenza B component of the 2013-2014 Northern Hemisphere trivalent and quadrivalent influenza vaccines.
* Victoria Lineage [39]: 39 influenza B/Victoria-lineage viruses were characterized as B/Brisbane/60/2008-like, which is included as an influenza B component of the 2013-2014 Northern Hemisphere quadrivalent influenza vaccine.

http://www.cdc.gov/flu/weekly/
 
Re: USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-13: 3 New Pediatric Deaths, 82 Total

Re: USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-13: 3 New Pediatric Deaths, 82 Total

Wk 13, ending Mar 29

Influenza-Associated Pediatric Mortality
Three influenza-associated pediatric deaths were reported to CDC during week 13. Two deaths were associated with influenza A viruses for which no subtyping was performed and occurred during weeks 9 and 12 (weeks ending March 1 and March 22, 2014). One death was associated with an influenza B virus and occurred during week 13 (week ending March 29, 2014). From the MMWR: 3 = NJ (1 ), TX (1 ), CA (1 )

A total of 82 influenza-associated pediatric deaths have been reported during the 2013-2014 season from Chicago [1], New York City [2] and 29 states (AR [4]; AZ [1]; CA [8]; FL [4]; GA [1]; IA [1]; IL [1]; KS [2]; KY [1]; LA [5]; MA [2]; MD [1]; ME [1]; MI [2]; MS [1]; NC [5]; NE [1]; NJ [1]; NV [1]; OK [2]; OR [1]; PA [3]; SC [2]; TN [4]; TX [17]; UT [2]; VA [1]; WI [2]; and WV [2]).

Influenza-Associated Hospitalizations
Between October 1, 2013 and March 29, 2014, 8,587 laboratory-confirmed influenza-associated hospitalizations were reported. This is a rate of 31.7 per 100,000 population. The highest rate of hospitalization remains among adults aged ≥65 years, followed by the 50-64 years and 0-4 years age groups. People 18-64 years accounted for approximately 60% of reported hospitalized cases. Among all hospitalizations, 7,941 (92.6%) were associated with influenza A, 553 (6.4%) with influenza B, 38 (0.4%) with influenza A and B co-infection, and 55 (0.6%) had no virus type information. Among those with influenza A subtype information, 124 (3.2%) were H3 and 3,741 (96.8%) were 2009 H1N1.

Clinical findings are preliminary and based on approximately 53% of cases with complete medical chart abstraction. The most commonly reported underlying medical conditions among adults were obesity, metabolic disorders, cardiovascular disease, and chronic lung disease (excluding asthma). Approximately 12% of hospitalized adults had no identified underlying medical conditions. The most commonly reported underlying medical conditions in children were asthma, neurologic disorders, chronic lung disease (excluding asthma), and obesity. Approximately 43% of hospitalized children had no identified underlying medical conditions. Among 630 hospitalized women of childbearing age (15-44 years), 143 (22.7%) were pregnant.

U.S. Virologic Surveillance for Wk 13
No. of specimens tested: 5,206
No. of positive specimens (%): 652 (12.5%)
Positive specimens by type/subtype
Influenza A: 315 (48.3%)
2009 H1N1: 68 (21.6%)
H3: 90 (28.6%)
Subtyping not performed: 157 (49.8%)
Influenza B: 337 (51.7%)

Neuraminidase Inhibitor Resistance Testing Results Since Oct 1, 2013
2009 H1N1: 4714 tested, 55 (1.2%) are resistant
All other samples tested found 0 resistant

Antigenic Characterization*
CDC has antigenically characterized 2,110 influenza viruses [1,657 2009 H1N1 viruses, 269 influenza A (H3N2) viruses, and 184 influenza B viruses] collected by U.S. laboratories since October 1, 2013 by hemagglutination inhibition (HI).

2009 H1N1 [1,657]:
* 1,656 (99.9%) of 1,657 2009 H1N1 viruses tested were characterized as A/California/7/2009-like, the influenza A (H1N1) component of the 2013-2014 Northern Hemisphere influenza vaccine. One (0.1%) virus showed reduced titers with antiserum produced against A/California/7/2009.

Influenza A (H3N2) [269]:
* 264 (98.1%) of the 269 influenza A (H3N2) viruses tested have been characterized as A/Texas/50/2012-like, the influenza A (H3N2) component of the 2013-2014 Northern Hemisphere influenza vaccine. Five (1.9%) viruses showed reduced titers with antiserum produced against A/Texas/50/2012.

Influenza B [184]: 124 (67%) of the 184 influenza B viruses tested belong to B/Yamagata/16/88-lineage and the remaining 60 (33%) influenza B viruses tested belong to B/Victoria/02/87 lineage.
* Yamagata Lineage [124]: 124 influenza B/Yamagata-lineage viruses were characterized as B/ Massachusetts/2/2012-like, which is included as an influenza B component of the 2013-2014 Northern Hemisphere trivalent and quadrivalent influenza vaccines.
* Victoria Lineage [60]: 60 influenza B/Victoria-lineage viruses were characterized as B/Brisbane/60/2008-like, which is included as an influenza B component of the 2013-2014 Northern Hemisphere quadrivalent influenza vaccine.

http://www.cdc.gov/flu/weekly/
 
Re: USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-13: 3 New Pediatric Deaths, 82 Total

Re: USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-13: 3 New Pediatric Deaths, 82 Total

Something to watch:

From above FluView:
Neuraminidase Inhibitor Resistance Testing Results Since Oct 1, 2013
2009 H1N1: 4714 tested, 55 (1.2%) are resistant

But the future..?

"Our findings suggest that recent A(H1N1)pdm09 viruses are now more permissive to the acquisition of H275Y than earlier A(H1N1)pdm09 viruses, increasing the risk that OR A(H1N1)pdm09 will emerge and spread worldwide."

http://www.flutrackers.com/forum/showthread.php?p=530286&highlight=coston#post530286
 
Re: USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-14: 3 New Pediatric Deaths, 85 Total

Re: USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-14: 3 New Pediatric Deaths, 85 Total

Wk 14, ending Apr 5

Influenza-Associated Pediatric Mortality
Three influenza-associated pediatric deaths were reported to CDC during week 14. Reported in the MMWR: 3 = NYC (1), NC (1), TX (1)

One death was associated with an influenza A virus for which no subtyping was performed and occurred during week 52 (week ending December 28, 2013). Two deaths were associated with influenza B viruses and occurred during week 13 (week ending March 29, 2014).

A total of 85 influenza-associated pediatric deaths have been reported during the 2013-2014 season from Chicago [1], New York City [3] and 29 states (AR [4]; AZ [1]; CA [8]; FL [4]; GA [1]; IA [1]; IL [1]; KS [2]; KY [1]; LA [5]; MA [2]; MD [1]; ME [1]; MI [2]; MS [1]; NC [6]; NE [1]; NJ [1]; NV [1]; OK [2]; OR [1]; PA [3]; SC [2]; TN [4]; TX [18]; UT [2]; VA [1]; WI [2]; and WV [2]).

Influenza-Associated Hospitalizations
Between October 1, 2013 and April 5, 2014, 8,777 laboratory-confirmed influenza-associated hospitalizations were reported. This is a rate of 32.4 per 100,000 population. The highest rate of hospitalization remains among adults aged ≥65 years, followed by the 50-64 years and 0-4 years age groups. People 18-64 years accounted for approximately 60% of reported hospitalized cases. Among all hospitalizations, 8,053 (91.8%) were associated with influenza A, 629 (7.2%) with influenza B, 40 (0.4%) with influenza A and B co-infection, and 55 (0.6%) had no virus type information. Among those with influenza A subtype information, 139 (3.5%) were H3 and 3,790 (96.5%) were 2009 H1N1.

Clinical findings are preliminary and based on approximately 57% of cases with complete medical chart abstraction. The most commonly reported underlying medical conditions among adults were obesity, metabolic disorders, cardiovascular disease, and chronic lung disease (excluding asthma). Approximately 12% of hospitalized adults had no identified underlying medical conditions. The most commonly reported underlying medical conditions in children were asthma, neurologic disorders, chronic lung disease (excluding asthma), and cardiovascular disease. Approximately 43% of hospitalized children had no identified underlying medical conditions. Among 688 hospitalized women of childbearing age (15-44 years), 161 (23.4%) were pregnant.

U.S. Virologic Surveillance for Wk 14
No. of specimens tested: 5,127
No. of positive specimens (%): 685 (13.4%)
Positive specimens by type/subtype
Influenza A: 302 (44.1%)
2009 H1N1: 57 (18.9%)
H3: 124 (41.1%)
Subtyping not performed: 121 (40.1%)
Influenza B: 383 (55.9%)

Neuraminidase Inhibitor Resistance Testing Results Since Oct 1, 2013
2009 H1N1: 4817 tested, 56 (1.2%) are resistant
All other samples tested found 0 resistant

Antigenic Characterization*
CDC has antigenically characterized 2,207 influenza viruses [1,753 2009 H1N1 viruses, 270 influenza A (H3N2) viruses, and 184 influenza B viruses] collected by U.S. laboratories since October 1, 2013 by hemagglutination inhibition (HI).

2009 H1N1 [1,753]:
* 1,752 (99.9%) of 1,753 2009 H1N1 viruses tested were characterized as A/California/7/2009-like, the influenza A (H1N1) component of the 2013-2014 Northern Hemisphere influenza vaccine. One (0.1%) virus showed reduced titers with antiserum produced against A/California/7/2009.

Influenza A (H3N2) [270]:
* 264 (97.8%) of the 270 influenza A (H3N2) viruses tested have been characterized as A/Texas/50/2012-like, the influenza A (H3N2) component of the 2013-2014 Northern Hemisphere influenza vaccine. Six (2.2%) viruses showed reduced titers with antiserum produced against A/Texas/50/2012.

Influenza B [184]: 124 (67%) of the 184 influenza B viruses tested belong to B/Yamagata/16/88-lineage and the remaining 60 (33%) influenza B viruses tested belong to B/Victoria/02/87 lineage.
* Yamagata Lineage [124]: 124 influenza B/Yamagata-lineage viruses were characterized as B/ Massachusetts/2/2012-like, which is included as an influenza B component of the 2013-2014 Northern Hemisphere trivalent and quadrivalent influenza vaccines.
* Victoria Lineage [60]: 60 influenza B/Victoria-lineage viruses were characterized as B/Brisbane/60/2008-like, which is included as an influenza B component of the 2013-2014 Northern Hemisphere quadrivalent influenza vaccine.

http://www.cdc.gov/flu/weekly/
 
Re: USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-15: 1 New Pediatric Deaths, 86 Total

Re: USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-15: 1 New Pediatric Deaths, 86 Total

Wk 15, ending Apr 15

Influenza-Associated Pediatric Mortality
One influenza-associated pediatric death was reported to CDC during week 15. This death was associated with an influenza B virus and occurred during week 14 (week ending April 5, 2014) As reported in the MMWR, the pediatric death occurred in NYC.

A total of 86 influenza-associated pediatric deaths have been reported during the 2013-2014 season from Chicago [1], New York City [4] and 29 states (AR [4]; AZ [1]; CA [8]; FL [4]; GA [1]; IA [1]; IL [1]; KS [2]; KY [1]; LA [5]; MA [2]; MD [1]; ME [1]; MI [2]; MS [1]; NC [6]; NE [1]; NJ [1]; NV [1]; OK [2]; OR [1]; PA [3]; SC [2]; TN [4]; TX [18]; UT [2]; VA [1]; WI [2]; and WV [2]).

Influenza-Associated Hospitalizations
Between October 1, 2013 and April 12, 2014, 8,995 laboratory-confirmed influenza-associated hospitalizations were reported. This is a rate of 33.2 per 100,000 population. The highest rate of hospitalization is among adults aged ≥65 years, with a steady increase in weekly rates observed in the past few weeks. Nonetheless. people aged 18-64 years still accounted for approximately 60% of reported hospitalized cases. Among all hospitalizations, 8,171 (90.8%) were associated with influenza A, 730 (8.1%) with influenza B, 43 (0.5%) with influenza A and B co-infection, and 51 (0.6%) had no virus type information. Among those with influenza A subtype information, 153 (3.8%) were H3 and 3,872 (96.2%) were 2009 H1N1.

Clinical findings are preliminary and based on approximately 60% of cases with complete medical chart abstraction. The most commonly reported underlying medical conditions among adults were obesity, metabolic disorders, cardiovascular disease, and chronic lung disease (excluding asthma). Approximately 12% of hospitalized adults had no identified underlying medical conditions. The most commonly reported underlying medical conditions in children were asthma, neurologic disorders, chronic lung disease (excluding asthma), and cardiovascular disease. Approximately 44% of hospitalized children had no identified underlying medical conditions. Among 730 hospitalized women of childbearing age (15-44 years), 167 (23%) were pregnant.

U.S. Virologic Surveillance for Wk 15
No. of specimens tested: 4,653
No. of positive specimens: 675 (14.5%)
Positive specimens by type/subtype
Influenza A: 301 (44.6%)
2009 H1N1: 20 (6.6%)
H3: 138 (45.8%)
Subtyping not performed: 143 (47.5%)
Influenza B: 374 (55.4%)

Neuraminidase Inhibitor Resistance Testing Results Since Oct 1, 2013
2009 H1N1: 4899 tested, 56 (1.1%) are resistant
All other samples tested found 0 resistant

Antigenic Characterization*
CDC has antigenically characterized 2,309 influenza viruses [1,755 2009 H1N1 viruses, 307 influenza A (H3N2) viruses, and 247 influenza B viruses] collected by U.S. laboratories since October 1, 2013 by hemagglutination inhibition (HI).

2009 H1N1 [1,755]:
* 1,752 (99.8%) of 1,755 2009 H1N1 viruses tested were characterized as A/California/7/2009-like, the influenza A (H1N1) component of the 2013-2014 Northern Hemisphere influenza vaccine. Three (0.2%) viruses showed reduced titers with antiserum produced against A/California/7/2009.

Influenza A (H3N2) [307]:
* 301 (98.0%) of the 307 influenza A (H3N2) viruses tested have been characterized as A/Texas/50/2012-like, the influenza A (H3N2) component of the 2013-2014 Northern Hemisphere influenza vaccine. Six (2.0%) viruses showed reduced titers with antiserum produced against A/Texas/50/2012.

Influenza B [247]: 172 (69.6%) of the 247 influenza B viruses tested belong to B/Yamagata/16/88-lineage and the remaining 75 (30.4%) influenza B viruses tested belong to B/Victoria/02/87 lineage.
* Yamagata Lineage [172]: 172 influenza B/Yamagata-lineage viruses were characterized as B/ Massachusetts/2/2012-like, which is included as an influenza B component of the 2013-2014 Northern Hemisphere trivalent and quadrivalent influenza vaccines.
* Victoria Lineage [75]: 75 influenza B/Victoria-lineage viruses were characterized as B/Brisbane/60/2008-like, which is included as an influenza B component of the 2013-2014 Northern Hemisphere quadrivalent influenza vaccine.

http://www.cdc.gov/flu/weekly/
 
Re: USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-16: 3 New Pediatric Deaths, 89 Total

Re: USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-16: 3 New Pediatric Deaths, 89 Total

Wk 16, ending Apr 19

Influenza-Associated Pediatric Mortality
Three influenza-associated pediatric deaths were reported to CDC during week 16. The MMWR reported: NY (1), LA (1) and NJ (1). One death was associated with 2009 H1N1 virus and occurred during week 6 (week ending February 8, 2014) and two deaths were associated with influenza B viruses and occurred during weeks 10 and 11 (weeks ending March 8 and March 15, 2014).

A total of 89 influenza-associated pediatric deaths have been reported during the 2013-2014 season from Chicago [1], New York City [4] and 30 states (AR [4]; AZ [1]; CA [8]; FL [4]; GA [1]; IA [1]; IL [1]; KS [2]; KY [1]; LA [6]; MA [2]; MD [1]; ME [1]; MI [2]; MS [1]; NC [6]; NE [1]; NJ [2]; NV [1]; NY[1]; OK [2]; OR [1]; PA [3]; SC [2]; TN [4]; TX [18]; UT [2]; VA [1]; WI [2]; and WV [2]).

Influenza-Associated Hospitalizations
Between October 1, 2013 and April 19, 2014, 9,173 laboratory-confirmed influenza-associated hospitalizations were reported. This is a rate of 33.9 per 100,000 population. The highest rate of hospitalization is among adults aged ≥65 years, with a steady increase in weekly rates observed in past few weeks. Nonetheless, people 18-64 years still accounted for approximately 60% of reported hospitalized cases. Among all hospitalizations, 8,256 (90.0%) were associated with influenza A, 824 (9.0%) with influenza B, 42 (0.5%) with influenza A and B co-infection, and 51 (0.5%) had no virus type information. Among those with influenza A subtype information, 181 (4.3%) were H3 and 3,974 (95.7%) were 2009 H1N1.

Clinical findings are preliminary and based on approximately 60% of cases with complete medical chart abstraction. The most commonly reported underlying medical conditions among adults were obesity, metabolic disorders, cardiovascular disease, and chronic lung disease (excluding asthma). Approximately 12% of hospitalized adults had no identified underlying medical conditions. The most commonly reported underlying medical conditions in children were asthma, neurologic disorders, chronic lung disease (excluding asthma), and cardiovascular disease. Approximately 44% of hospitalized children had no identified underlying medical conditions. Among 772 hospitalized women of childbearing age (15-44 years), 173 (22%) were pregnant.

U.S. Virologic Surveillance for Wk 16
No. of specimens tested: 5,061
No. of positive specimens: 606 (12.0%)

Positive specimens by type/subtype
Influenza A: 266 (43.9%)
2009 H1N1: 14 (5.3%)
H3: 127 (47.7%)
Subtyping not performed: 125 (47.0%)
Influenza B: 340 (56.1%)

Neuraminidase Inhibitor Resistance Testing Results Since Oct 1, 2013
2009 H1N1: 4968 tested, 59 (1.2%) are resistant
All other samples tested found 0 resistant

Antigenic Characterization
CDC has antigenically characterized 2,408 influenza viruses [1,854 2009 H1N1 viruses, 307 influenza A (H3N2) viruses, and 247 influenza B viruses] collected by U.S. laboratories since October 1, 2013 by hemagglutination inhibition (HI).

2009 H1N1 [1,854]:
* 1,851 (99.8%) of 1,854 2009 H1N1 viruses tested were characterized as A/California/7/2009-like, the influenza A (H1N1) component of the 2013-2014 Northern Hemisphere influenza vaccine. Three (0.2%) viruses showed reduced titers with antiserum produced against A/California/7/2009.

Influenza A (H3N2) [307]:
* 301 (98.0%) of the 307 influenza A (H3N2) viruses tested have been characterized as A/Texas/50/2012-like, the influenza A (H3N2) component of the 2013-2014 Northern Hemisphere influenza vaccine. Six (2.0%) viruses showed reduced titers with antiserum produced against A/Texas/50/2012.

Influenza B [247]: 172 (69.6%) of the 247 influenza B viruses tested belong to B/Yamagata/16/88-lineage and the remaining 75 (30.4%) influenza B viruses tested belong to B/Victoria/02/87 lineage.
* Yamagata Lineage [172]: 172 influenza B/Yamagata-lineage viruses were characterized as B/ Massachusetts/2/2012-like, which is included as an influenza B component of the 2013-2014 Northern Hemisphere trivalent and quadrivalent influenza vaccines.
*Victoria Lineage [75]: 75 influenza B/Victoria-lineage viruses were characterized as B/Brisbane/60/2008-like, which is included as an influenza B component of the 2013-2014 Northern Hemisphere quadrivalent influenza vaccine.

http://www.cdc.gov/flu/weekly/
 
Re: USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-17: 2 New Pediatric Deaths, 91 Total

Re: USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-17: 2 New Pediatric Deaths, 91 Total

Wk 17, ending Apr 26

Influenza-Associated Pediatric Mortality
Two influenza-associated pediatric deaths were reported to CDC during week 17. As reported in the MMWR, 2 pediatric deaths happened in VA. One death was associated with an influenza A (H3) virus and occurred during week 15 (week ending April 12, 2014) and one death was associated with an influenza A virus and for which no subtyping was performed and occurred during week 16 (week ending April 19, 2014).

A total of 91 influenza-associated pediatric deaths have been reported during the 2013-2014 season from Chicago [1], New York City [4] and 30 states (AR [4]; AZ [1]; CA [8]; FL [4]; GA [1]; IA [1]; IL [1]; KS [2]; KY [1]; LA [6]; MA [2]; MD [1]; ME [1]; MI [2]; MS [1]; NC [6]; NE [1]; NJ [2]; NV [1]; NY[1]; OK [2]; OR [1]; PA [3]; SC [2]; TN [4]; TX [18]; UT [2]; VA [3]; WI [2]; and WV [2]).

Influenza-Associated Hospitalizations
Between October 1, 2013 and April 26, 2014, 9,460 laboratory-confirmed influenza-associated hospitalizations were reported. This is a rate of 34.9 per 100,000 population. The highest rate of hospitalization is among adults aged ≥65 years, with a steady increase in weekly rates observed in past few weeks. Nonetheless people 18-64 years still accounted for approximately 60% of reported hospitalized cases. Among all hospitalizations, 8,433 (89.1%) were associated with influenza A, 932 (9.9%) with influenza B, 43 (0.5%) with influenza A and B co-infection, and 52 (0.5%) had no virus type information. Among those with influenza A subtype information, 202 (4.8%) were H3 and 4,018 (95.2%) were 2009 H1N1.

Clinical findings are preliminary and based on approximately 60% of cases with complete medical chart abstraction. The most commonly reported underlying medical conditions among adults were obesity, metabolic disorders, cardiovascular disease, and chronic lung disease (excluding asthma). Approximately 12% of hospitalized adults had no identified underlying medical conditions. The most commonly reported underlying medical conditions in children were asthma, neurologic disorders, chronic lung disease (excluding asthma), and cardiovascular disease. Approximately 44% of hospitalized children had no identified underlying medical conditions. Among 800 hospitalized women of childbearing age (15-44 years), 179 (22%) were pregnant.

U.S. Virologic Surveillance for Wk 17
No. of specimens tested: 4,031
No. of positive specimens: 500 (12.4%)
Positive specimens by type/subtype
Influenza A: 223 (44.6%)
2009 H1N1: 8 (3.6%)
H3: 92 (41.3%)
Subtyping not performed: 123 (55.2%)
Influenza B: 277 (55.4%)

Neuraminidase Inhibitor Resistance Testing Results Since Oct 1, 2013
2009 H1N1: 5062 tested, 59 (1.2%) are resistant
All other samples tested found 0 resistant

Antigenic Characterization
CDC has antigenically characterized 2,529 influenza viruses [1,929 2009 H1N1 viruses, 308 influenza A (H3N2) viruses, and 292 influenza B viruses] collected by U.S. laboratories since October 1, 2013 by hemagglutination inhibition (HI).

2009 H1N1 [1,929]:
* 1,926 (99.8%) of 1,929 2009 H1N1 viruses tested were characterized as A/California/7/2009-like, the influenza A (H1N1) component of the 2013-2014 Northern Hemisphere influenza vaccine. Three (0.2%) viruses showed reduced titers with antiserum produced against A/California/7/2009.

Influenza A (H3N2) [308]:
* 301 (97.7%) of the 308 influenza A (H3N2) viruses tested have been characterized as A/Texas/50/2012-like, the influenza A (H3N2) component of the 2013-2014 Northern Hemisphere influenza vaccine. Seven (2.3%) viruses showed reduced titers with antiserum produced against A/Texas/50/2012.

Influenza B [292]: 205 (70.2%) of the 292 influenza B viruses tested belong to B/Yamagata/16/88-lineage and the remaining 87 (29.8%) influenza B viruses tested belong to B/Victoria/02/87 lineage.
* Yamagata Lineage [205]: 205 influenza B/Yamagata-lineage viruses were characterized as B/ Massachusetts/2/2012-like, which is included as an influenza B component of the 2013-2014 Northern Hemisphere trivalent and quadrivalent influenza vaccines.
* Victoria Lineage [87]: 87 influenza B/Victoria-lineage viruses were characterized as B/Brisbane/60/2008-like, which is included as an influenza B component of the 2013-2014 Northern Hemisphere quadrivalent influenza vaccine.

http://www.cdc.gov/flu/weekly/
 
Re: USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-18: 0 New Pediatric Deaths, 91 Total

Re: USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-18: 0 New Pediatric Deaths, 91 Total

Wk 18, ending May 3

Influenza-Associated Pediatric Mortality
No influenza-associated pediatric deaths were reported to CDC during week 18.

A total of 91 influenza-associated pediatric deaths have been reported during the 2013-2014 season from Chicago [1], New York City [4] and 30 states (AR [4]; AZ [1]; CA [8]; FL [4]; GA [1]; IA [1]; IL [1]; KS [2]; KY [1]; LA [6]; MA [2]; MD [1]; ME [1]; MI [2]; MS [1]; NC [6]; NE [1]; NJ [2]; NV [1]; NY[1]; OK [2]; OR [1]; PA [3]; SC [2]; TN [4]; TX [18]; UT [2]; VA [3]; WI [2]; and WV [2]).

Influenza-Associated Hospitalizations
Between October 1, 2013 and April 30, 2014, 9,587 laboratory-confirmed influenza-associated hospitalizations were reported. This is a rate of 35.4 per 100,000 population. The highest rate of hospitalization is among adults aged ≥65 years, although those aged 18-64 years account for approximately 60% of reported hospitalized cases. Among all hospitalizations, 8,483 (88.5%) were associated with influenza A, 1,010 (10.5%) with influenza B, 45 (0.5%) with influenza A and B co-infection, and 49 (0.5%) had no virus type information. Among those with influenza A subtype information, 221 (5.2%) were H3 and 4,044 (94.8%) were 2009 H1N1.

Clinical findings are preliminary and based on approximately 64% of cases with complete medical chart abstraction. The most commonly reported underlying medical conditions among adults were obesity, metabolic disorders, cardiovascular disease, and chronic lung disease (excluding asthma). Approximately 11% of hospitalized adults had no identified underlying medical conditions. The most commonly reported underlying medical conditions in children were asthma, neurologic disorders, chronic lung disease (excluding asthma), and cardiovascular disease. Approximately 43% of hospitalized children had no identified underlying medical conditions. Among 820 hospitalized women of childbearing age (15-44 years), 186 (23%) were pregnant.

U.S. Virologic Surveillance for Wk 18
No. of specimens tested: 3,692
No. of positive specimens: 460 (12.5%)
Positive specimens by type/subtype
Influenza A: 202 (43.9%)
2009 H1N1: 5 (2.5%)
H3: 80 (39.6%)
Subtyping not performed: 117 (57.9%)
Influenza B: 258 (56.1%)

Neuraminidase Inhibitor Resistance Testing Results Since Oct 1, 2013
2009 H1N1: 5071 tested, 59 (1.2%) are resistant
All other samples tested found 0 resistant

Antigenic Characterization
CDC has antigenically characterized 2,644 influenza viruses [1,929 2009 H1N1 viruses, 421 influenza A (H3N2) viruses, and 294 influenza B viruses] collected by U.S. laboratories since October 1, 2013 by hemagglutination inhibition (HI).

2009 H1N1 [1,929]:
* 1,926 (99.8%) of 1,929 2009 H1N1 viruses tested were characterized as A/California/7/2009-like, the influenza A (H1N1) component of the 2013-2014 Northern Hemisphere influenza vaccine. Three (0.2%) viruses showed reduced titers with antiserum produced against A/California/7/2009.

Influenza A (H3N2) [421]:
* 406 (96.4%) of the 421 influenza A (H3N2) viruses tested have been characterized as A/Texas/50/2012-like, the influenza A (H3N2) component of the 2013-2014 Northern Hemisphere influenza vaccine. Fifteen (2.3%) viruses showed reduced titers with antiserum produced against A/Texas/50/2012.

Influenza B [294]: 206 (70.1%) of the 294 influenza B viruses tested belong to B/Yamagata/16/88-lineage and the remaining 88 (29.9%) influenza B viruses tested belong to B/Victoria/02/87 lineage.
* Yamagata Lineage [206]: 205 (99.5%) of the 206 influenza B/Yamagata-lineage viruses were characterized as B/ Massachusetts/2/2012-like, which is included as an influenza B component of the 2013-2014 Northern Hemisphere trivalent and quadrivalent influenza vaccines. One (0.5%) virus showed reduced titers with antiserum produced against B/Massachusetts/2/2012.
* Victoria Lineage [88]: 88 influenza B/Victoria-lineage viruses were characterized as B/Brisbane/60/2008-like, which is included as an influenza B component of the 2013-2014 Northern Hemisphere quadrivalent influenza vaccine.

http://www.cdc.gov/flu/weekly/
 
Re: USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-19: 3 New Pediatric Deaths, 94 Total

Re: USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-19: 3 New Pediatric Deaths, 94 Total

Wk 19, ending May 10

Influenza-Associated Pediatric Mortality
Three influenza-associated pediatric deaths were reported to CDC during week 19. Reported in the MMWR: MI (1), VA (1), NYC (1). One death was associated with an influenza A (H3) virus and occurred during week 16 (week ending April 19, 2014) and one death was associated with an influenza A virus for which no subtyping was performed and occurred during week 17 (week ending April 26, 2014). One death was associated with influenza B virus and occurred during week 17 (week ending April 26, 2014).

A total of 94 influenza-associated pediatric deaths have been reported during the 2013-2014 season from Chicago [1], New York City [5] and 30 states (AR [4]; AZ [1]; CA [8]; FL [4]; GA [1]; IA [1]; IL [1]; KS [2]; KY [1]; LA [6]; MA [2]; MD [1]; ME [1]; MI [3]; MS [1]; NC [6]; NE [1]; NJ [2]; NV [1]; NY[1]; OK [2]; OR [1]; PA [3]; SC [2]; TN [4]; TX [18]; UT [2]; VA [4]; WI [2]; and WV [2]).

Influenza-Associated Hospitalizations
Between October 1, 2013 and April 30, 2014, 9,619 laboratory-confirmed influenza-associated hospitalizations were reported. This is a rate of 35.4 per 100,000 population. The highest rate of hospitalization is among adults aged ≥65 years, although those aged 18-64 years account for approximately 60% of reported hospitalized cases. Among all hospitalizations, 8,489 (88.3%) were associated with influenza A, 1,038 (10.8%) with influenza B, 43 (0.4%) with influenza A and B co-infection, and 49 (0.5%) had no virus type information. Among those with influenza A subtype information, 236 (5.4%) were H3 and 4,142 (94.6%) were 2009 H1N1.

Clinical findings are preliminary and based on approximately 67% of cases with complete medical chart abstraction. The most commonly reported underlying medical conditions among adults were obesity, metabolic disorders, cardiovascular disease, and chronic lung disease (excluding asthma). Approximately 11% of hospitalized adults had no identified underlying medical conditions. The most commonly reported underlying medical conditions in children were asthma, neurologic disorders, chronic lung disease (excluding asthma), and cardiovascular disease. Approximately 43% of hospitalized children had no identified underlying medical conditions. Among 841 hospitalized women of childbearing age (15-44 years), 190 (23%) were pregnant.

U.S. Virologic Surveillance for Wk 19
No. of specimens tested: 3,381
No. of positive specimens: 342 (10.1%)
Positive specimens by type/subtype
Influenza A: 142 (41.5%)
2009 H1N1: 0
H3: 59 (41.5%)
Subtyping not performed: 83 (58.5%)
Influenza B: 200 (58.5%)

Neuraminidase Inhibitor Resistance Testing Results Since Oct 1, 2013
2009 H1N1: 5092 tested, 59 (1.2%) are resistant
All other samples tested found 0 resistant

Antigenic Characterization
CDC has antigenically characterized 2,815 influenza viruses [2,008 2009 H1N1 viruses, 426 influenza A (H3N2) viruses, and 381 influenza B viruses] collected by U.S. laboratories since October 1, 2013 by hemagglutination inhibition (HI).

2009 H1N1 [2,008]:
* 2,005 (99.8%) of 2,008 2009 H1N1 viruses tested were characterized as A/California/7/2009-like, the influenza A (H1N1) component of the 2013-2014 Northern Hemisphere influenza vaccine. Three (0.2%) viruses showed reduced titers with antiserum produced against A/California/7/2009.

Influenza A (H3N2) [426]:
* 406 (95.3%) of the 426 influenza A (H3N2) viruses tested have been characterized as A/Texas/50/2012-like, the influenza A (H3N2) component of the 2013-2014 Northern Hemisphere influenza vaccine. Twenty (4.7%) viruses showed reduced titers with antiserum produced against A/Texas/50/2012.

Influenza B [381]: 269 (70.6%) of the 381 influenza B viruses tested belong to B/Yamagata/16/88-lineage and the remaining 112 (29.4%) influenza B viruses tested belong to B/Victoria/02/87 lineage.
*Yamagata Lineage [269]: 268 (99.6%) of the 269 influenza B/Yamagata-lineage viruses were characterized as B/ Massachusetts/2/2012-like, which is included as an influenza B component of the 2013-2014 Northern Hemisphere trivalent and quadrivalent influenza vaccines. One (0.4%) virus showed reduced titers with antiserum produced against B/Massachusetts/2/2012.
* Victoria Lineage [112]: 112 influenza B/Victoria-lineage viruses were characterized as B/Brisbane/60/2008-like, which is included as an influenza B component of the 2013-2014 Northern Hemisphere quadrivalent influenza vaccine.

http://www.cdc.gov/flu/weekly/
 
Re: USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-20: 1 New Pediatric Deaths, 95 Total

Re: USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-20: 1 New Pediatric Deaths, 95 Total

Wk 20, ending May 17

Influenza-Associated Pediatric Mortality
One influenza-associated pediatric death was reported to CDC during week 20. As reported in the MMWR: IL (1). This death was associated with an influenza B virus and occurred during week 19 (week ending May 10, 2014).

A total of 95 influenza-associated pediatric deaths have been reported during the 2013-2014 season from Chicago [1], New York City [5] and 30 states (AR [4]; AZ [1]; CA [8]; FL [4]; GA [1]; IA [1]; IL [2]; KS [2]; KY [1]; LA [6]; MA [2]; MD [1]; ME [1]; MI [3]; MS [1]; NC [6]; NE [1]; NJ [2]; NV [1]; NY[1]; OK [2]; OR [1]; PA [3]; SC [2]; TN [4]; TX [18]; UT [2]; VA [4]; WI [2]; and WV [2])

Influenza-Associated Hospitalizations
Between October 1, 2013 and April 30, 2014, 9,632 laboratory-confirmed influenza-associated hospitalizations were reported. This is a rate of 35.6 per 100,000 population. The highest rate of hospitalization is among adults aged ≥65 years, although those aged 18-64 years account for approximately 60% of reported hospitalized cases. Among all hospitalizations, 8,493 (88.2%) were associated with influenza A, 1,047 (10.9%) with influenza B, 43 (0.4%) with influenza A and B co-infection, and 49 (0.5%) had no virus type information. Among those with influenza A subtype information, 268 (6.0%) were H3 and 4,213 (94.0%) were 2009 H1N1.

Clinical findings are preliminary and based on 70% of cases with complete medical chart abstraction. The most commonly reported underlying medical conditions among adults were obesity, metabolic disorders, cardiovascular disease, and chronic lung disease (excluding asthma). Approximately 11% of hospitalized adults had no identified underlying medical conditions. The most commonly reported underlying medical conditions in children were asthma, neurologic disorders, cardiovascular disease, and chronic lung disease (excluding asthma). Approximately 43% of hospitalized children had no identified underlying medical conditions. Among 869 hospitalized women of childbearing age (15-44 years), 195 (22.4%) were pregnant.

U.S. Virologic Surveillance for Wk 20
No. of specimens tested: 3,885
No. of positive specimens: 339 (8.7%)
Positive specimens by type/subtype
Influenza A: 139 (41.0%)
2009 H1N1: 0 (0.0%)
H3: 50 (36.0%)
Subtyping not performed: 89 (64.0%)
Influenza B 200 (59.0%)

Neuraminidase Inhibitor Resistance Testing Results Since Oct 1, 2013
2009 H1N1: 5100 tested, 59 (1.2%) are resistant
All other samples tested found 0 resistant

Antigenic Characterization
CDC has antigenically characterized 2,815 influenza viruses [2,008 2009 H1N1 viruses, 426 influenza A (H3N2) viruses, and 381 influenza B viruses] collected by U.S. laboratories since October 1, 2013 by hemagglutination inhibition (HI).

2009 H1N1 [2,008]:
* 2,005 (99.8%) of 2,008 2009 H1N1 viruses tested were characterized as A/California/7/2009-like, the influenza A (H1N1) component of the 2013-2014 Northern Hemisphere influenza vaccine. Three (0.2%) viruses showed reduced titers with antiserum produced against A/California/7/2009.

Influenza A (H3N2) [426]:
* 406 (95.3%) of the 426 influenza A (H3N2) viruses tested have been characterized as A/Texas/50/2012-like, the influenza A (H3N2) component of the 2013-2014 Northern Hemisphere influenza vaccine. Twenty (4.7%) viruses showed reduced titers with antiserum produced against A/Texas/50/2012.

Influenza B [381]: 269 (70.6%) of the 381 influenza B viruses tested belong to B/Yamagata/16/88-lineage and the remaining 112 (29.4%) influenza B viruses tested belong to B/Victoria/02/87 lineage.
* Yamagata Lineage [269]: 268 (99.6%) of the 269 influenza B/Yamagata-lineage viruses were characterized as B/ Massachusetts/2/2012-like, which is included as an influenza B component of the 2013-2014 Northern Hemisphere trivalent and quadrivalent influenza vaccines. One (0.4%) virus showed reduced titers with antiserum produced against B/Massachusetts/2/2012.
* Victoria Lineage [112]: 112 influenza B/Victoria-lineage viruses were characterized as B/Brisbane/60/2008-like, which is included as an influenza B component of the 2013-2014 Northern Hemisphere quadrivalent influenza vaccine.

http://www.cdc.gov/flu/weekly/
 
Re: USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-21: 1 New Pediatric Deaths, 96 Total

Re: USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-21: 1 New Pediatric Deaths, 96 Total

Notice on the CDC site: The May 11-17, 2014 FluView marks the final full influenza surveillance report for the 2013-2014 flu season in the United States. Influenza surveillance in the U.S. will continue through the summer months with condensed reports available at http://www.cdc.gov/flu/weekly/, though the summary key points available on this page will no longer be updated.

Wk 21, ending May 24

Influenza-Associated Pediatric Mortality:
One influenza-associated pediatric death was reported to CDC during week 21. Reported in the MMWR: NJ (1), This death was associated with 2009 H1N1 virus and occurred during week 10 (week ending March 8, 2014). A total of 96 influenza-associated pediatric deaths have been reported during the 2013-2014 season.

Outpatient Illness Surveillance:
Nationwide during week 21, 1.3% of patient visits reported through the U.S. Outpatient Influenza-like Illness Surveillance Network (ILINet) were due to influenza-like illness (ILI). This percentage is below the national baseline of 2.2%.

http://www.cdc.gov/flu/weekly/
 
Re: USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-22: 1 New Pediatric Death, 97 Total

Re: USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-22: 1 New Pediatric Death, 97 Total

Wk 22, ending May 31

Influenza-Associated Pediatric Mortality:
One influenza-associated pediatric death was reported to CDC during week 22. As reported in the MMWR: AZ (1). This death was associated with an influenza B virus and occurred during week 22 (week ending May 31, 2014). A total of 97 influenza-associated pediatric deaths have been reported during the 2013-2014 season.

Outpatient Illness Surveillance:
Nationwide during week 22, 1.0% of patient visits reported through the U.S. Outpatient Influenza-like Illness Surveillance Network (ILINet) were due to influenza-like illness (ILI). This percentage is below the national baseline of 2.0%.

http://www.cdc.gov/flu/weekly/
 
Re: USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-23: 0 New Pediatric Deaths, 97 Total

Re: USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-23: 0 New Pediatric Deaths, 97 Total

Wk 23, ending June 7

Influenza-Associated Pediatric Mortality:
No influenza-associated pediatric deaths were reported to CDC during week 23. A total of 97 influenza-associated pediatric deaths have been reported during the 2013-2014 season.

Pneumonia and Influenza (P&I) Mortality Surveillance:
During week 23, 5.7 % of all deaths reported through the 122-Cities Mortality Reporting System were due to P&I. This percentage was below the epidemic threshold of 6.6% for week 23.

Outpatient Illness Surveillance:
Nationwide during week 23, 1.0% of patient visits reported through the U.S. Outpatient Influenza-like Illness Surveillance Network (ILINet) were due to influenza-like illness (ILI). This percentage is below the national baseline of 2.0%.

http://www.cdc.gov/flu/weekly/
 
Re: USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-26: 1 New Pediatric Deaths, 100 Total

Re: USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-26: 1 New Pediatric Deaths, 100 Total

Wk 24, ending June 14

Influenza-Associated Pediatric Mortality:
No influenza-associated pediatric deaths were reported to CDC during week 24. A total of 97 influenza-associated pediatric deaths have been reported during the 2013-2014 season.

Pneumonia and Influenza (P&I) Mortality Surveillance:
During week 24, 5.3 % of all deaths reported through the 122-Cities Mortality Reporting System were due to P&I. This percentage was below the epidemic threshold of 6.5% for week 24.

Outpatient Illness Surveillance:
Nationwide during week 24, 0.9% of patient visits reported through the U.S. Outpatient Influenza-like Illness Surveillance Network (ILINet) were due to influenza-like illness (ILI). This percentage is below the national baseline of 2.0%.
http://www.cdc.gov/flu/weekly/weeklyarchives2013-2014/weekly24.html


Wk 25, ending June 21

Influenza-Associated Pediatric Mortality:
Two influenza-associated pediatric deaths were reported to CDC during week 25. Both deaths were associated with an influenza A (H3) virus and occurred during weeks 18 and 21 (weeks ending May 3 and May 24, 2014). A total of 99 influenza-associated pediatric deaths have been reported during the 2013-2014 season.

Pneumonia and Influenza (P&I) Mortality Surveillance:
During week 25, 5.9 % of all deaths reported through the 122-Cities Mortality Reporting System were due to P&I. This percentage was below the epidemic threshold of 6.4% for week 25.

Outpatient Illness Surveillance:
Nationwide during week 24, 0.9% of patient visits reported through the U.S. Outpatient Influenza-like Illness Surveillance Network (ILINet) were due to influenza-like illness (ILI). This percentage is below the national baseline of 2.0%.
http://www.cdc.gov/flu/weekly/weeklyarchives2013-2014/weekly25.html


Wk 26, ending June 28

Influenza-Associated Pediatric Mortality:
One influenza-associated pediatric death was reported to CDC during week 26. This death was associated with an influenza B virus and occurred during week 23 (week ending June 7, 2014). A total of 100 influenza-associated pediatric deaths have been reported during the 2013-2014 season.

Pneumonia and Influenza (P&I) Mortality Surveillance:
During week 26, 5.5% of all deaths reported through the 122-Cities Mortality Reporting System were due to P&I. This percentage was below the epidemic threshold of 6.3% for week 26.

Outpatient Illness Surveillance:
Nationwide during week 26, 1.1% of patient visits reported through the U.S. Outpatient Influenza-like Illness Surveillance Network (ILINet) were due to influenza-like illness (ILI). This percentage is below the national baseline of 2.0%.
http://www.cdc.gov/flu/weekly/
 
Re: USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-29: 4 New Pediatric Deaths, 105 Total

Re: USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-29: 4 New Pediatric Deaths, 105 Total

NOTE: As of week 28, I updated the subject line of each of the 30 states reported to have pediatric deaths to show the total numbers, according to the CDC. As any new ones are reported, I'll bump that state up.

*********************************
Wk 27 reports no influenza-associated pediatric deaths

Wk 28, ending July 12
Influenza-Associated Pediatric Mortality:
One influenza-associated pediatric death was reported to CDC during week 28. This death was associated with an influenza A (H3) virus and occurred during week 16 (April 19, 2014). A total of 101 influenza-associated pediatric deaths have been reported during the 2013-2014 season.
http://www.cdc.gov/flu/weekly/weeklyarchives2013-2014/weekly28.html

Wk 29, ending July 19
Pneumonia and Influenza (P&I) Mortality Surveillance:
During week 29, 5.5 % of all deaths reported through the 122-Cities Mortality Reporting System were due to P&I. This percentage was below the epidemic threshold of 6.1% for week 29.

Influenza-Associated Pediatric Mortality:
Four influenza-associated pediatric deaths were reported to CDC during week 29. Three deaths were associated with an influenza A virus for which no subtyping was performed and occurred during weeks 5, 18, and 23 (weeks ending February 1, May 3, and June 7, 2014). One death was associated with an influenza B virus and occurred during week 18 (May 3, 2014). A total of 105 influenza-associated pediatric deaths have been reported during the 2013-2014 season.

http://www.cdc.gov/flu/weekly/

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Week 20 was the last week the CDC reported the pediatric mortality cases by states. Here it is:

Influenza-Associated Pediatric Mortality
One influenza-associated pediatric death was reported to CDC during week 20. This death was associated with an influenza B virus and occurred during week 19 (week ending May 10, 2014).

A total of 95 influenza-associated pediatric deaths have been reported during the 2013-2014 season from Chicago [1], New York City [5] and 30 states (AR [4]; AZ [1]; CA [8]; FL [4]; GA [1]; IA [1]; IL [2]; KS [2]; KY [1]; LA [6]; MA [2]; MD [1]; ME [1]; MI [3]; MS [1]; NC [6]; NE [1]; NJ [2]; NV [1]; NY[1]; OK [2]; OR [1]; PA [3]; SC [2]; TN [4]; TX [18]; UT [2]; VA [4]; WI [2]; and WV [2]).

***************
Here I have updated the states (in bold) to week 28. when a total of 101 was reported. And now this week, we have an additional 4, which I have added in red. From the MMWR: NJ 2, MN 1, TX 1

A total of 101 (now 105) influenza-associated pediatric deaths have been reported during the 2013-2014 season from Chicago [1], New York City [5] and 30 states (AR [4]; AZ [2]; CA [8]; FL [4]; GA [1]; IA [1]; IL [2]; KS [2]; KY [1]; LA [6]; MA [2]; MD [1]; ME [1]; MI [3]; MN [1] + 1, MS [1]; NC [6]; NE [1]; NJ [4 +2; NM [1], NV [2]; NY[1]; OK [2]; OR [1]; PA [3]; SC [2]; TN [4]; TX [18] + 1; UT [2]; VA [4]; WI [2]; and WV [2]).
 
Re: USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-31: 106 Total Pediatric Deaths

Re: USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-31: 106 Total Pediatric Deaths

Wk 31, ending Aug 2

Influenza-Associated Pediatric Mortality:
One influenza-associated pediatric death was reported to CDC during week 31. This death was associated with an influenza A virus for which no subtyping was performed and occurred during week 4 (week ending January 25, 2014). From this week's MMWR: CA [1]

A total of 106 influenza-associated pediatric deaths have been reported during the 2013-2014 season: Chicago [1], New York City [5] and 30 states (AR [4]; AZ [2]; CA [9]; FL [4]; GA [1]; IA [1]; IL [2]; KS [2]; KY [1]; LA [6]; MA [2]; MD [1]; ME [1]; MI [3]; MN [2], MS [1]; NC [6]; NE [1]; NJ [6]; NM [1], NV [2]; NY[1]; OK [2]; OR [1]; PA [3]; SC [2]; TN [4]; TX [19]; UT [2]; VA [4]; WI [2]; and WV [2]).

http://www.cdc.gov/flu/weekly/
 
Re: USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-34: 107 Total Pediatric Deaths

Re: USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-34: 107 Total Pediatric Deaths

Note: There was one additional pediatric death in CA reported in week 32.

Influenza-Associated Pediatric Mortality:
One influenza-associated pediatric death was reported to CDC during week 32. This death was associated with an influenza A virus for which no subtyping was performed and occurred during week 4 (week ending January 25, 2014). A total of 107 influenza-associated pediatric deaths have been reported during the 2013-2014 season.
http://www.cdc.gov/flu/weekly/weeklyarchives2013-2014/weekly32.html

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Week 34, ending Aug 23

Novel Influenza A Viruses:

One new human infection with a novel influenza A virus was reported by Ohio. The person was infected with an influenza A (H3N2) variant (H3N2v) virus and was not hospitalized as a result of their illness. No ongoing human-to-human transmission has been identified and the case reported close contact with swine in the week prior to illness onset. Public health and agriculture officials are investigating the extent of disease among humans and swine and no increases in influenza-like illness in the community have been reported. Genetic sequencing of the H3N2v virus conducted at CDC showed that this virus has the nucleoprotein (NP) and matrix (M) gene from the 2009 H1N1 virus, and was similar to the H3N2v virus identified previously this summer. A total of two H3N2v cases have been reported in 2014 and are not epidemiologically linked.

Early identification and investigation of human infections with novel influenza A viruses is critical in order to evaluate the extent of the outbreak and possible human-to-human transmission. Additional information on influenza in swine, variant influenza infection in humans, and strategies to interact safely with livestock can be found at http://www.cdc.gov/flu/swineflu/h3n2v-cases.htm.

Influenza-Associated Pediatric Mortality:
No influenza-associated pediatric deaths were reported to CDC during week 34. A total of 107 influenza-associated pediatric deaths have been reported during the 2013-2014 season.

A total of 107 influenza-associated pediatric deaths have been reported during the 2013-2014 season: Chicago [1], New York City [5] and 30 states (AR [4]; AZ [2]; CA [10]; FL [4]; GA [1]; IA [1]; IL [2]; KS [2]; KY [1]; LA [6]; MA [2]; MD [1]; ME [1]; MI [3]; MN [2], MS [1]; NC [6]; NE [1]; NJ [6]; NM [1], NV [2]; NY[1]; OK [2]; OR [1]; PA [3]; SC [2]; TN [4]; TX [19]; UT [2]; VA [4]; WI [2]; and WV [2]).

http://www.cdc.gov/flu/weekly/
 
Re: USA: 2013-14 FluView: Influenza Season Weekly Summary, Wks 42-38: 108 Total Pediatric Deaths

Week 37, ending Sept 13

Influenza-Associated Pediatric Mortality:
One influenza-associated pediatric death was reported to CDC during week 37. This death was associated with an influenza A virus for which no subtyping was performed and occurred during week 32 (week ending August 9, 2014). A total of 108 influenza-associated pediatric deaths have been reported during the 2013-2014 season.

A total of 108 influenza-associated pediatric deaths have been reported during the 2013-2014 season: Chicago [1], New York City [5] and 30 states (AR [4]; AZ [2]; CA [10]; FL [4]; GA [1]; IA [1]; IL [2]; KS [2]; KY [1]; LA [6]; MA [2]; MD [1]; ME [1]; MI [3]; MN [2], MS [1]; NC [6]; NE [1]; NJ [6]; NM [1], NV [2]; NY[1]; OK [2]; OR [1]; PA [3]; SC [2]; TN [4]; TX [20]; UT [2]; VA [4]; WI [2]; and WV [2]).

Outpatient Illness Surveillance:
Nationwide during week 37, 1.1% of patient visits reported through the U.S. Outpatient Influenza-like Illness Surveillance Network (ILINet) were due to influenza-like illness (ILI). This percentage is below the national baseline of 2.0%.

Pneumonia and Influenza (P&I) Mortality Surveillance:
During week 37, 5.5 % of all deaths reported through the 122-Cities Mortality Reporting System were due to P&I. This percentage was below the epidemic threshold of 6.0% for week 37.
http://www.cdc.gov/flu/weekly/weeklyarchives2013-2014/weekly37.html

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Week 38, ending Sept 20

Novel Influenza A Viruses:
No additional human infections with novel influenzas A viruses were reported during week 38. A total of two H3N2v cases have been reported in 2014 and are not epidemiologically linked.

Pneumonia and Influenza (P&I) Mortality Surveillance:
During week 38, 5.2% of all deaths reported through the 122-Cities Mortality Reporting System were due to P&I. This percentage was below the epidemic threshold of 6.0% for week 38.

Influenza-Associated Pediatric Mortality:
No new influenza-associated pediatric deaths were reported to CDC during week 38. A total of 108 influenza-associated pediatric deaths have been reported during the 2013-2014 season.

Outpatient Illness Surveillance:
Nationwide during week 38, 1.1% of patient visits reported through the U.S. Outpatient Influenza-like Illness Surveillance Network (ILINet) were due to influenza-like illness (ILI). This percentage is below the national baseline of 2.0%.

http://www.cdc.gov/flu/weekly/
 
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