tetano
Editor, Senior Moderator
ScienceDaily (June 7, 2011) ? A universal influenza vaccine targeting a protein common to all strains of influenza A has safely produced an immune response in humans. If proven effective, the vaccine could eliminate the practice of creating a new flu vaccine annually to match predicted strains, with major implications for global health.
The results of the clinical trials, led by the University of Texas Medical Branch at Galveston in collaboration with biotechnology company VaxInnate and funded by $9.5 million grant from the Bill and Melinda Gates Foundation, were published online in the journal Vaccine.
The vaccine candidate, VAX102, targets a protein known as M2e, found on the surface of the influenza A virus, that has remained relatively unchanged over the last century. VAX102 consists of 4 copies of M2e fused to the protein flagellin, a TLR5 ligand used as an adjuvant. The M2e antigen had been completely unchanged from 1918 until the recent pandemic, making it of interest to researchers searching for a target for the immune response to influenza that would be stable over many seasons.
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http://www.sciencedaily.com/release...encedaily (ScienceDaily: Latest Science News)
The results of the clinical trials, led by the University of Texas Medical Branch at Galveston in collaboration with biotechnology company VaxInnate and funded by $9.5 million grant from the Bill and Melinda Gates Foundation, were published online in the journal Vaccine.
The vaccine candidate, VAX102, targets a protein known as M2e, found on the surface of the influenza A virus, that has remained relatively unchanged over the last century. VAX102 consists of 4 copies of M2e fused to the protein flagellin, a TLR5 ligand used as an adjuvant. The M2e antigen had been completely unchanged from 1918 until the recent pandemic, making it of interest to researchers searching for a target for the immune response to influenza that would be stable over many seasons.
..
http://www.sciencedaily.com/release...encedaily (ScienceDaily: Latest Science News)