Re: U.K.: Experts baffled by deadly disease killing dogs in New Forest & other forested areas
Alabama Rot ? an unexplained dog illness
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Where have cases been to date?
The following table outlines all cases being referred to as Alabama Rot (identified and confirmed) to date from across the UK (not just walks including the Forestry Commission?s Public Forest Estate). It will be kept updated with new information as received from Anderson Moores Veterinary Specialists who have been collating information on the cases and leading the investigation.
Please note that we will aim to keep this table updated as promptly as possible, but we are not able to update the information in response to media reported cases or those from individuals. This is to ensure that what is published is as accurate as possible, coming from Anderson Moores who can verify cases as accurately as possible through scientific investigation.
?Unconfirmed? cases are either awaiting test results, or may never be confirmed if no tissue was available for examination.
Locations in green include cases found on the Forestry Commission?s Public Forest Estate. Click on the location for more information.
LAST UPDATED 16th April 2014:
<TABLE border=1 cellSpacing=0 cellPadding=5><TBODY><TR><TD vAlign=top width=568 colSpan=2>
Cases Dec 2012 ? May 2013
</TD></TR><TR><TD vAlign=top width=284>
Confirmed 13
</TD><TD vAlign=top width=284>
Unconfirmed 2
</TD></TR><TR><TD vAlign=top width=284>5
New Forest, Hampshire
1 Upton, Poole, Dorset
7 elsewhere UK (including: Cornwall; Worcestershire; County Durham; Surrey, Nottinghamshire)
</TD><TD vAlign=top width=284>2 New Forest, Hampshire
</TD></TR><TR><TD vAlign=top width=568 colSpan=2>
Cases Dec 2013 ? Present
</TD></TR><TR><TD vAlign=top width=284>
Confirmed 21
</TD><TD vAlign=top width=284>
Unconfirmed 18
</TD></TR><TR><TD vAlign=top width=284>7
New Forest, Hampshire
1 Yorkshire
1 Monmouthshire
3 Dorset
1 Shropshire
2 Surrey
1 Northamptonshire
1 Somerset
1 Petersfield, Hampshire
1 Lancashire
2 Greater Manchester
</TD><TD vAlign=top width=284>10
New Forest, Hampshire
2 Cheshire
1 Co. Antrim
1 Dorset
1 West Sussex
1 Greater Manchester
1 Somerset
1 Kent
(1 survivor)
</TD></TR><TR><TD vAlign=top width=284>Total: 34
</TD><TD vAlign=top width=284>Total: 20
</TD></TR></TBODY></TABLE>
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http://www.forestry.gov.uk/alabamarot
[h=2]Abstract[/h] To describe the signalment, clinicopathological findings and outcome in dogs presenting with acute kidney injury (AKI) and skin lesions between November 2012 and March 2014, in whom cutaneous and renal glomerular vasculopathy (CRGV) was suspected and renal thrombotic microangiopathy (TMA) was histopathologically confirmed. The medical records of dogs with skin lesions and AKI, with histopathologically confirmed renal TMA, were retrospectively reviewed. Thirty dogs from across the UK were identified with clinicopathological findings compatible with CRGV. These findings included the following: skin lesions, predominantly affecting the distal extremities; AKI; and variably, anaemia, thrombocytopaenia and hyperbilirubinaemia. Known causes of AKI were excluded. The major renal histopathogical finding was TMA. All thirty dogs died or were euthanised. Shiga toxin was not identified in the kidneys of affected dogs. Escherichia coli genes encoding shiga toxin were not identified in faeces from affected dogs. CRGV has previously been reported in greyhounds in the USA, a greyhound in the UK, without renal involvement, and a Great Dane in Germany. This is the first report of a series of non-greyhound dogs with CRGV and AKI in the UK. CRGV is a disease of unknown aetiology carrying a poor prognosis when azotaemia develops.